EC 3.5.1.18: succinyl-diaminopimelate desuccinylase
HydrolasesOpen in Browse
CatLog read 7 records for EC 3.5.1.18 from 2 papers, for 2 organisms. Names in these papers: N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded), DapE (N-succinyl-L,L-diaminopimelate desuccinylase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 19 records for EC 3.5.1.18 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.18 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Hydrolysis of N-succinyl-L,L-diaminopimelic acid by the Haemophilus influenzae dapE-encoded desuccinylase: metal activation, solvent isotope effects, and kinetic mechanism | Haemophilus influenzae | 4 |
| DapE can function as an aspartyl peptidase in the presence of Mn2+ | Salmonella enterica serovar Typhimurium | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| DapE (N-succinyl-L,L-diaminopimelate desuccinylase) | Salmonella enterica serovar Typhimurium | Asp-Leu | 113 | 3.3 | 34 calc. | pH 8, 37 °C | PMID 12896993 | Open record: DapE (N-succinyl-L,L-diaminopimelate desuccinylase), Asp-Leu |
| DapE (N-succinyl-L,L-diaminopimelate desuccinylase) | Salmonella enterica serovar Typhimurium | Asp-Ser | 96 | 0.66 | 150 calc. | pH 8, 37 °C | PMID 12896993 | Open record: DapE (N-succinyl-L,L-diaminopimelate desuccinylase), Asp-Ser |
| DapE (N-succinyl-L,L-diaminopimelate desuccinylase) | Salmonella enterica serovar Typhimurium | N-succinyl-L,L-diaminopimelate | 242 | 0.63 | 380 calc. | pH 8, 37 °C | PMID 12896993 | Open record: DapE (N-succinyl-L,L-diaminopimelate desuccinylase), N-succinyl-L,L-diaminopimelate |
| N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded) | Haemophilus influenzae | N-succinyl-diaminopimelic acid, approximately equimolar mixture of the D,D- and L,L- isomersZnSO4 (Zn2+ as metal activator, as printed) | 230 | 3.2 | 72 calc. | pH 7.6, 25 °C | PMID 9671518 | Open record: N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded), N-succinyl-diaminopimelic acid, approximately equimolar mixture of the D,D- and L,L- isomers |
| N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded) | Haemophilus influenzae | N-succinyl-diaminopimelic acid, approximately equimolar mixture of the D,D- and L,L- isomersCoSO4 (Co2+ as metal activator, as printed) | 470 | 4.7 | 100 calc. | pH 7.6, 25 °C | PMID 9671518 | Open record: N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded), N-succinyl-diaminopimelic acid, approximately equimolar mixture of the D,D- and L,L- isomers |
| N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded) | Haemophilus influenzae | N-succinyl-L,L-diaminopimelic acidZnSO4 (Zn2+ as metal activator, as printed) | 200 | 1.3 | 150 calc. | pH 7.6, 25 °C | PMID 9671518 | Open record: N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded), N-succinyl-L,L-diaminopimelic acid |
| N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded) | Haemophilus influenzae | N-succinyl-L,L-diaminopimelic acidCoSO4 (Co2+ as metal activator, as printed) | 370 | 1.6 | 230 calc. | pH 7.6, 25 °C | PMID 9671518 | Open record: N-succinyl-L,L-diaminopimelic acid desuccinylase (dapE-encoded), N-succinyl-L,L-diaminopimelic acid |