CatLogenzyme kinetics catalog

EC 3.5.1.23: ceramidase

HydrolasesOpen in Browse

CatLog read 36 records for EC 3.5.1.23 from 3 papers, for 2 organisms. Names in these papers: N-acylethanolamine acid amidase (NAAA), neutral ceramidase (NC), alkaline ceramidase 2 (ACER2).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 28 records for EC 3.5.1.23 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.23 in Browse.

Papers

PaperOrganismsRecords
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidaseRattus norvegicus15
New fluorogenic probes for neutral and alkaline ceramidasesHomo sapiens11
Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)Homo sapiens10

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
alkaline ceramidase 2 (ACER2)Homo sapiensd-e-C18:1-ceramide—0.07731—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensd-e-C20:1-ceramide—0.07211—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensd-e-C24:1-ceramide—0.0814—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-dodecanoyl-D-erythro-sphingosine—0.1338—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-eicosanoyl-D-erythro-sphingosine—0.09147—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-hexadecanoyl-D-erythro-sphingosine—0.09852—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-hexanoyl-D-erythro-sphingosine—0.2242—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-octadecanoyl-D-erythro-sphingosine—0.09481—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-tetracosanoyl-D-erythro-sphingosine—0.1432—pH 9, 37 °CPMID 20089856Open
alkaline ceramidase 2 (ACER2)Homo sapiensN-tetradecanoyl-D-erythro-sphingosine—0.1146—pH 9, 37 °CPMID 20089856Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(R)-N-(1-hydroxypropan-2-yl)hexadecanamide—0.01932—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(S)-N-(1-hydroxypropan-2-yl)hexadecanamide—0.03234—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(Z)-N-(2-hydroxyethyl)eicos-9-enamide—0.2317—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(Z)-N-(2-hydroxyethyl)heptadec-10-enamide—0.1282—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(Z)-N-(2-hydroxyethyl)hexadec-9-enamide—0.07281—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(Z)-N-(2-hydroxyethyl)nonadec-10-enamide—0.161—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(Z)-N-(2-hydroxyethyl)octadec-9-enamide—0.1673—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicus(Z)-N-(2-hydroxyethyl)pentadec-10-enamide—0.05429—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicushexadecanamide—0.01829—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicusN-(2-hydroxyethyl)heptadecanamide—0.00654—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicusN-(2-hydroxyethyl)hexadecanamide—0.01981—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicusN-(2-hydroxyethyl)pentadecanamide—0.02546—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicusN-(2-hydroxyethyl)tetradecanamide—0.07286—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicusN-(2-hydroxyethyl)tridecanamide—0.02628—pH 4.5, 37 °CPMID 34256657Open
N-acylethanolamine acid amidase (NAAA)Rattus norvegicusN-methylhexadecanamide—0.01808—pH 4.5, 37 °CPMID 34256657Open
neutral ceramidase (NC)Homo sapiensRBM14C163.281——pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM14C18:10.4320.0280.0154pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM14C20(R)OH2.6550.0160.1659pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM14C20(S)OH3.0750.0140.2196pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM14C22:11.3970.0280.0499pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM14C24:11.5810.0080.1976pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM15C18:13.7610.1390.0271pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM15C20(R)OH22.950.0420.5465pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM15C20(S)OH7.2570.0210.3456pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM15C22:14.9770.0330.1508pH 7.4, 37 °CPMID 30926626Open
neutral ceramidase (NC)Homo sapiensRBM15C24:18.4150.040.2104pH 7.4, 37 °CPMID 30926626Open