EC 3.5.1.24: choloylglycine hydrolase
HydrolasesOpen in Browse
CatLog read 47 records for EC 3.5.1.24 from 5 papers, for 5 organisms. Names in these papers: bile salt hydrolase BSH1, bile salt hydrolase (BlBSH), bile salt hydrolase BSH2, bile salt hydrolase 1 (BSH1) and 3 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 26 records for EC 3.5.1.24 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.24 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| doi:10.1016/j.molcatb.2013.06.010 | Lactobacillus salivarius | 14 |
| Structural and functional analysis of a conjugated bile salt hydrolase from Bifidobacterium longum reveals an evolutionary relationship with penicillin V acylase | Bifidobacterium longum | 10 |
| Electrostatic Interactions Dictate Bile Salt Hydrolase Substrate Preference | Clostridium perfringens, Lactiplantibacillus plantarum | 10 |
| Development of a covalent inhibitor of gut bacterial bile salt hydrolases | Bacteroides thetaiotaomicron, Bifidobacterium longum | 7 |
| Identification and characterization of a bile salt hydrolase from Lactobacillus salivarius for development of novel alternatives to antibiotic growth promoters | Lactobacillus salivarius | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | glycochenodeoxycholic acid | — | 0.28 | — | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), glycochenodeoxycholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | glycocholic acidTable 2 | 85 | 0.022 | 3.8 × 10³ | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), glycocholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | glycocholic acidTable 4 | — | 0.22 | — | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), glycocholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | glycodeoxycholic acid | — | 0.18 | — | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), glycodeoxycholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | taurochenodeoxycholic acid | — | 0.42 | — | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), taurochenodeoxycholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | taurocholic acidTable 2 | 76 | 0.032 | 2.4 × 10³ | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), taurocholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | taurocholic acidTable 4 | — | 0.32 | — | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), taurocholic acid |
| bile salt hydrolase (BlBSH) | Bifidobacterium longum | taurodeoxycholic acid | — | 0.49 | — | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH), taurodeoxycholic acid |
| bile salt hydrolase (BlBSH)variant T2A | Bifidobacterium longum | glycocholic acid | 44 | 0.024 | 1.8 × 10³ | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH) variant T2A, glycocholic acid |
| bile salt hydrolase (BlBSH)variant T2A | Bifidobacterium longum | taurocholic acid | 40 | 0.03 | 1.3 × 10³ | pH 6.5, 40 °C | PMID 16905539 | Open record: bile salt hydrolase (BlBSH) variant T2A, taurocholic acid |
| bile salt hydrolase (BSH) | Bifidobacterium longum | taurochenodeoxycholic acid | 0.077 | 7 | 0.01 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH), taurochenodeoxycholic acid |
| bile salt hydrolase (BSH) | Bifidobacterium longum | taurocholic acid | 0.115 | 8.3 | 0.013 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH), taurocholic acid |
| bile salt hydrolase (BSH) | Bifidobacterium longum | taurodeoxycholic acid | 0.058 | 2.3 | 0.025 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH), taurodeoxycholic acid |
| bile salt hydrolase (BSH) | Bifidobacterium longum | tauroursodeoxycholic acid | 0.015 | 4.1 | 0.0033 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH), tauroursodeoxycholic acid |
| bile salt hydrolase (BSH, BT_2086) | Bacteroides thetaiotaomicron | taurochenodeoxycholic acid | 0.072 | 2.9 | 0.072 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH, BT_2086), taurochenodeoxycholic acid |
| bile salt hydrolase (BSH, BT_2086) | Bacteroides thetaiotaomicron | taurodeoxycholic acid | 0.215 | 3.4 | 0.063 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH, BT_2086), taurodeoxycholic acid |
| bile salt hydrolase (BSH, BT_2086) | Bacteroides thetaiotaomicron | tauroursodeoxycholic acid | 0.255 | 8.2 | 0.032 | pH 7.5, 37 °C | PMID 32042200 | Open record: bile salt hydrolase (BSH, BT_2086), tauroursodeoxycholic acid |
| bile salt hydrolase 1 (BSH1) | Lactiplantibacillus plantarum | glycocholate | 774.6 | 1.3 | 597 | pH 6.2, 37 °C | PMID 37883888 | Open record: bile salt hydrolase 1 (BSH1), glycocholate |
| bile salt hydrolase 1 (BSH1) | Lactiplantibacillus plantarum | leucine-conjugated cholic acid | 0.7 | 1.122 | 0.62 | pH 6.2, 37 °C | PMID 37883888 | Open record: bile salt hydrolase 1 (BSH1), leucine-conjugated cholic acid |
| bile salt hydrolase 1 (BSH1) | Lactiplantibacillus plantarum | phenylalanine-conjugated cholic acid | 16.08 | — | — | pH 6.2, 37 °C | PMID 37883888 | Open record: bile salt hydrolase 1 (BSH1), phenylalanine-conjugated cholic acid |
| bile salt hydrolase 1 (BSH1) | Lactiplantibacillus plantarum | taurocholate | 13.4 | 1.918 | 7 | pH 6.2, 37 °C | PMID 37883888 | Open record: bile salt hydrolase 1 (BSH1), taurocholate |
| bile salt hydrolase 1 (BSH1) | Lactiplantibacillus plantarum | tyrosine-conjugated cholic acid | 25.78 | — | — | pH 6.2, 37 °C | PMID 37883888 | Open record: bile salt hydrolase 1 (BSH1), tyrosine-conjugated cholic acid |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | glycochenodeoxycholic acid | 15.63 | 2.48 | 6.3 | pH 6, 37 °C | PMID 23064348 | Open record: bile salt hydrolase BSH1, glycochenodeoxycholic acid |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | glycocholic acid | 8.87 | 1.71 | 5.18 | pH 6, 37 °C | PMID 23064348 | Open record: bile salt hydrolase BSH1, glycocholic acid |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | glycodeoxycholic acid | 6.37 | 1.15 | 5.53 | pH 6, 37 °C | PMID 23064348 | Open record: bile salt hydrolase BSH1, glycodeoxycholic acid |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium glycochenodeoxycholateabsence of DTT | 70.07 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium glycochenodeoxycholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium glycochenodeoxycholatewith DTT (concentration not stated in this paper) | 33.52 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium glycochenodeoxycholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium glycocholate | 53.82 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium glycocholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium glycodeoxycholate | 48.76 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium glycodeoxycholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium taurochenodeoxycholate | 70.03 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium taurochenodeoxycholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium taurocholate | 91.53 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium taurocholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | sodium taurodeoxycholate | 83.15 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH1, sodium taurodeoxycholate |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | taurochenodeoxycholic acid | 8.5 | 2.53 | 3.35 | pH 6, 37 °C | PMID 23064348 | Open record: bile salt hydrolase BSH1, taurochenodeoxycholic acid |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | taurocholic acid | 9.75 | 3.21 | 3.03 | pH 6, 37 °C | PMID 23064348 | Open record: bile salt hydrolase BSH1, taurocholic acid |
| bile salt hydrolase BSH1 | Lactobacillus salivarius | taurodeoxycholic acid | 13.43 | 3.19 | 4.2 | pH 6, 37 °C | PMID 23064348 | Open record: bile salt hydrolase BSH1, taurodeoxycholic acid |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium glycochenodeoxycholateabsence of DTT | 82.59 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium glycochenodeoxycholate |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium glycochenodeoxycholatewith DTT (concentration not stated in this paper) | 35.32 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium glycochenodeoxycholate |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium glycocholate | 83.77 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium glycocholate |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium glycodeoxycholate | 80.87 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium glycodeoxycholate |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium taurochenodeoxycholate | 93.14 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium taurochenodeoxycholate |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium taurocholate | 93.11 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium taurocholate |
| bile salt hydrolase BSH2 | Lactobacillus salivarius | sodium taurodeoxycholate | 99.43 | — | — | pH 6, 37 °C | doi:10.1016/j.molcatb.2013.06.010 | Open record: bile salt hydrolase BSH2, sodium taurodeoxycholate |
| cholylglycine hydrolase (CGH) | Clostridium perfringens | glycocholate | 279.8 | 0.54 | 518 | pH 6.2, 37 °C | PMID 37883888 | Open record: cholylglycine hydrolase (CGH), glycocholate |
| cholylglycine hydrolase (CGH) | Clostridium perfringens | leucine-conjugated cholic acid | 0.0283 | 1.937 | 0.015 | pH 6.2, 37 °C | PMID 37883888 | Open record: cholylglycine hydrolase (CGH), leucine-conjugated cholic acid |
| cholylglycine hydrolase (CGH) | Clostridium perfringens | phenylalanine-conjugated cholic acid | 0.0103 | 1.007 | 0.01 | pH 6.2, 37 °C | PMID 37883888 | Open record: cholylglycine hydrolase (CGH), phenylalanine-conjugated cholic acid |
| cholylglycine hydrolase (CGH) | Clostridium perfringens | taurocholate | 367.9 | 0.477 | 772 | pH 6.2, 37 °C | PMID 37883888 | Open record: cholylglycine hydrolase (CGH), taurocholate |
| cholylglycine hydrolase (CGH) | Clostridium perfringens | tyrosine-conjugated cholic acid | 0.245 | 2.169 | 0.113 | pH 6.2, 37 °C | PMID 37883888 | Open record: cholylglycine hydrolase (CGH), tyrosine-conjugated cholic acid |