EC 3.5.1.48: acetylspermidine deacetylase
HydrolasesOpen in Browse
CatLog read 62 records for EC 3.5.1.48 from 1 paper, for 3 organisms. Names in these papers: histone deacetylase 10 (zHDAC10), histone deacetylase 10 (hHDAC10), acetylpolyamine amidohydrolase (APAH).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 6 records for EC 3.5.1.48 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.48 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Histone deacetylase 10 structure and molecular function as a polyamine deacetylase | Danio rerio, Homo sapiens and 1 more | 62 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin | 0.0067 | 0.12 | 0.05 | pH 8 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.017 | 0.11 | 0.15 | pH 8 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | acetylcadaverine | 1.5 | 0.022 | 68 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), acetylcadaverine |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | acetylputrescine | 1.5 | — | — | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), acetylputrescine |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | N-(3-aminopropyl)acetamide | 1.3 | 0.18 | 7 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), N-(3-aminopropyl)acetamide |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | N-(8-aminooctyl)acetamide | 1.1 | 0.11 | 10 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), N-(8-aminooctyl)acetamide |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | N-butylacetamide | — | — | 0.38 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), N-butylacetamide |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | N^1-acetylspermidine | 0.6 | 0.07 | 7.4 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), N^1-acetylspermidine |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | N^1-acetylspermine | 0.2 | 0.06 | 2.5 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), N^1-acetylspermine |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | N^8-acetylspermidine | 2.5 | 0.08 | 30 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), N^8-acetylspermidine |
| acetylpolyamine amidohydrolase (APAH) | Mycoplana ramosa | Nα,Nε-diacetyl-L-lysinamide | 0.13 | 0.22 | 0.6 | pH 7.5 | PMID 28516954 | Open record: acetylpolyamine amidohydrolase (APAH), Nα,Nε-diacetyl-L-lysinamide |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin | 3.8 × 10⁻⁴ | 0.01 | 0.038 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.008 | 0.11 | 0.07 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | acetylcadaverine | 0.14 | 0.11 | 1.3 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), acetylcadaverine |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | acetylputrescine | 0.35 | 0.17 | 2.1 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), acetylputrescine |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | N-(8-aminooctyl)acetamide | 0.1 | 0.16 | 0.62 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), N-(8-aminooctyl)acetamide |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | N-butylacetamide | — | — | 0.022 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), N-butylacetamide |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | N^1,N^8-diacetylspermidine | 0.14 | 0.15 | 0.9 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), N^1,N^8-diacetylspermidine |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | N^1-acetylspermidine | — | — | 0.024 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), N^1-acetylspermidine |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | N^1-acetylspermine | 0.011 | 0.18 | 0.06 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), N^1-acetylspermine |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | N^8-acetylspermidine | 0.28 | 0.1 | 2.9 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), N^8-acetylspermidine |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | Nα,Nε-diacetyl-L-lysinamide | 0.0092 | 0.14 | 0.066 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), Nα,Nε-diacetyl-L-lysinamide |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | Nα-acetyl-L-alanyl-Nε-acetyl-L-lysyl-L-alaninamide | 6 × 10⁻⁴ | 0.06 | 0.011 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), Nα-acetyl-L-alanyl-Nε-acetyl-L-lysyl-L-alaninamide |
| histone deacetylase 10 (hHDAC10) | Homo sapiens | Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl-glycinamide | — | — | 0.091 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (hHDAC10), Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl-glycinamide |
| histone deacetylase 10 (zHDAC10) | Danio rerio | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin | 3.3 × 10⁻⁴ | 0.022 | 0.015 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10) | Danio rerio | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarinHis-MBP tag removed | 3 × 10⁻⁵ | 0.04 | 0.001 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10) | Danio rerio | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.0015 | 0.066 | 0.023 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10) | Danio rerio | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarinHis-MBP tag removed | 0.0016 | 0.12 | 0.012 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10) | Danio rerio | acetylcadaverine | 0.37 | 0.09 | 3.9 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), acetylcadaverine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | acetylcadaverineHis-MBP tag removed | 0.036 | 0.06 | 0.6 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), acetylcadaverine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | acetylputrescine | 0.7 | 0.16 | 4.2 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), acetylputrescine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | acetylputrescineHis-MBP tag removed | 0.081 | 0.08 | 0.98 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), acetylputrescine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N-(3-aminopropyl)acetamide | — | — | 0.013 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N-(3-aminopropyl)acetamide |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N-(8-aminooctyl)acetamide | 0.21 | 0.17 | 1.2 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N-(8-aminooctyl)acetamide |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N-butylacetamide | 0.06 | 0.9 | 0.06 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N-butylacetamide |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N^1,N^8-diacetylspermidine | 0.48 | 0.18 | 2.7 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N^1,N^8-diacetylspermidine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N^1-acetylspermidine | — | — | 0.007 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N^1-acetylspermidine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N^1-acetylspermine | — | — | 0.017 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N^1-acetylspermine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N^1-acetylspermineHis-MBP tag removed | — | — | 0.006 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N^1-acetylspermine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N^8-acetylspermidine | 0.58 | 0.13 | 4.6 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N^8-acetylspermidine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | N^8-acetylspermidineHis-MBP tag removed | 0.06 | 0.07 | 0.8 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), N^8-acetylspermidine |
| histone deacetylase 10 (zHDAC10) | Danio rerio | Nα,Nε-diacetyl-L-lysinamide | 0.013 | 0.08 | 0.16 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), Nα,Nε-diacetyl-L-lysinamide |
| histone deacetylase 10 (zHDAC10) | Danio rerio | Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl-glycinamide | — | — | 0.026 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10), Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl-glycinamide |
| histone deacetylase 10 (zHDAC10)variant D94A | Danio rerio | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin | 4.6 × 10⁻⁴ | 0.017 | 0.027 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant D94A, 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant D94A | Danio rerio | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.0013 | 0.15 | 0.009 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant D94A, 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant D94A | Danio rerio | acetylcadaverine | 0.29 | 0.26 | 1.1 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant D94A, acetylcadaverine |
| histone deacetylase 10 (zHDAC10)variant D94A | Danio rerio | acetylputrescine | 0.24 | 0.11 | 2.2 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant D94A, acetylputrescine |
| histone deacetylase 10 (zHDAC10)variant D94A | Danio rerio | N^1-acetylspermine | — | — | 0.022 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant D94A, N^1-acetylspermine |
| histone deacetylase 10 (zHDAC10)variant D94A | Danio rerio | N^8-acetylspermidine | 0.9 | 0.14 | 6.2 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant D94A, N^8-acetylspermidine |
| histone deacetylase 10 (zHDAC10)variant E274L | Danio rerio | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin | 0.053 | 0.07 | 0.73 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant E274L, 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant E274L | Danio rerio | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.21 | 0.07 | 3.1 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant E274L, 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant E274L | Danio rerio | acetylcadaverine | 0.02 | 0.06 | 0.35 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant E274L, acetylcadaverine |
| histone deacetylase 10 (zHDAC10)variant E274L | Danio rerio | acetylputrescine | 0.034 | 0.16 | 0.22 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant E274L, acetylputrescine |
| histone deacetylase 10 (zHDAC10)variant E274L | Danio rerio | N^8-acetylspermidine | 0.028 | 0.13 | 0.21 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant E274L, N^8-acetylspermidine |
| histone deacetylase 10 (zHDAC10)variant N93A | Danio rerio | 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin | 7 × 10⁻⁵ | 0.06 | 0.001 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant N93A, 7-(Nα-acetyl-glycyl-L-alanyl-Nε-acetyl-L-lysyl)amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant N93A | Danio rerio | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.0013 | 0.11 | 0.012 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant N93A, 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant N93A | Danio rerio | acetylcadaverine | 0.051 | 0.05 | 0.94 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant N93A, acetylcadaverine |
| histone deacetylase 10 (zHDAC10)variant N93A | Danio rerio | acetylputrescine | 0.126 | 0.13 | 0.93 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant N93A, acetylputrescine |
| histone deacetylase 10 (zHDAC10)variant N93A | Danio rerio | N^1-acetylspermine | — | — | 0.05 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant N93A, N^1-acetylspermine |
| histone deacetylase 10 (zHDAC10)variant N93A | Danio rerio | N^8-acetylspermidine | 0.123 | 0.15 | 0.8 | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant N93A, N^8-acetylspermidine |
| histone deacetylase 10 (zHDAC10)variant ΔηA2 (helix ηA2 segment D24-I29 replaced by zHDAC6 CD2 L1-loop segment S461-P464) | Danio rerio | 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin | 0.021 | 0.06 | 0.36 | pH 8 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant ΔηA2 (helix ηA2 segment D24-I29 replaced by zHDAC6 CD2 L1-loop segment S461-P464), 7-(Nα-acetyl-L-arginyl-glycyl-Nε-acetyl-L-lysyl)-amino-4-methylcoumarin |
| histone deacetylase 10 (zHDAC10)variant ΔηA2 (helix ηA2 segment D24-I29 replaced by zHDAC6 CD2 L1-loop segment S461-P464) | Danio rerio | N^8-acetylspermidine | 0.082 | — | — | pH 7.5 | PMID 28516954 | Open record: histone deacetylase 10 (zHDAC10) variant ΔηA2 (helix ηA2 segment D24-I29 replaced by zHDAC6 CD2 L1-loop segment S461-P464), N^8-acetylspermidine |