CatLogenzyme kinetics catalog

EC 3.5.1.98: histone deacetylase

HydrolasesOpen in Browse

CatLog read 30 records for EC 3.5.1.98 from 2 papers, for 1 organism. Names in these papers: HDAC1, HDAC3, HDAC8, histone deacetylase 5 (HDAC5).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 23 records for EC 3.5.1.98 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.1.98 in Browse.

Papers

PaperOrganismsRecords
Factors affecting the substrate specificity of histone deacetylasesHomo sapiens27
In vitro characterization of the catalytic domain of human histone deacetylase 5Homo sapiens3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
HDAC1Homo sapiensN-acetyl-L-isoleucyl-L-histidyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—6.9 × 10⁻⁴—PMID 17428445Open
HDAC1Homo sapiensN-acetyl-L-leucyl-L-isoleucyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.00303—PMID 17428445Open
HDAC1Homo sapiensN-acetyl-L-leucyl-L-tyrosyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.02943—PMID 17428445Open
HDAC1Homo sapiensN-acetyl-L-phenylalanyl-L-alpha-glutamyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01171—PMID 17428445Open
HDAC1Homo sapiensN-acetyl-L-valyl-L-leucyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01502—PMID 17428445Open
HDAC1Homo sapiensN-acetylglycyl-L-seryl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01334—PMID 17428445Open
HDAC1Homo sapiensN-acetylglycyl-O-phospho-L-seryl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.04605—PMID 17428445Open
HDAC1Homo sapiensN-acetylglycylglycyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01385—PMID 17428445Open
HDAC1Homo sapiensN2-acetyl-L-lysyl-L-tryptophyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.005—PMID 17428445Open
HDAC1Homo sapiensN2-acetyl-L-lysyl-L-tyrosyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.00558—PMID 17428445Open
HDAC3Homo sapiensN-acetyl-L-alpha-aspartyl-L-glutaminyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.00244—PMID 17428445Open
HDAC3Homo sapiensN-acetyl-L-isoleucyl-L-histidyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01482—PMID 17428445Open
HDAC3Homo sapiensN-acetyl-L-isoleucyl-L-leucyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01243—PMID 17428445Open
HDAC3Homo sapiensN-acetyl-L-leucyl-L-tyrosyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0069—PMID 17428445Open
HDAC3Homo sapiensN-acetyl-L-phenylalanyl-L-alpha-glutamyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0046—PMID 17428445Open
HDAC3Homo sapiensN-acetyl-L-valyl-L-leucyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01194—PMID 17428445Open
HDAC3Homo sapiensN-acetylglycyl-L-seryl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.00405—PMID 17428445Open
HDAC3Homo sapiensN-acetylglycyl-O-phospho-L-seryl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.02765—PMID 17428445Open
HDAC3Homo sapiensN-acetylglycylglycyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01005—PMID 17428445Open
HDAC3Homo sapiensN2-acetyl-L-lysyl-L-tyrosyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.00745—PMID 17428445Open
HDAC8Homo sapiensN-acetyl-L-isoleucyl-L-histidyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0091—PMID 17428445Open
HDAC8Homo sapiensN-acetyl-L-phenylalanyl-L-alpha-glutamyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.03598—PMID 17428445Open
HDAC8Homo sapiensN-acetyl-L-prolyl-L-phenylalanyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.01—PMID 17428445Open
HDAC8Homo sapiensN-acetylglycyl-L-seryl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0108—PMID 17428445Open
HDAC8Homo sapiensN-acetylglycyl-O-phospho-L-seryl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0489—PMID 17428445Open
HDAC8Homo sapiensN-acetylglycylglycyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0391—PMID 17428445Open
HDAC8Homo sapiensN2-acetyl-L-lysyl-L-tyrosyl-N6-acetyl-L-lysine 4-methylcoumarin-7-amide—0.0044—PMID 17428445Open
histone deacetylase 5 (HDAC5)Homo sapiensBoc-Lys-(Tfa)-AMC1.6180.088118.3pH 8PMID 41760657Open
histone deacetylase 5 (HDAC5)variant H1006YHomo sapiensBoc-Lys-(Ac)-AMC0.9530.038924.5pH 8PMID 41760657Open
histone deacetylase 5 (HDAC5)variant H1006YHomo sapiensBoc-Lys-(Tfa)-AMC0.9280.046719.8pH 8PMID 41760657Open