EC 3.5.4.25: GTP cyclohydrolase II
HydrolasesOpen in Browse
CatLog read 28 records for EC 3.5.4.25 from 2 papers, for 2 organisms. Names in these papers: GTP cyclohydrolase II homologue SCO 6655, GTP cyclohydrolase II homologue SCO 2687, GTP cyclohydrolase II homologue SCO 1441, COG3236-RibA fusion protein.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 14 records for EC 3.5.4.25 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.5.4.25 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Understanding functional divergence in proteins by studying intragenomic homologues | Streptomyces coelicolor | 26 |
| A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis | Vibrio vulnificus | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| COG3236-RibA fusion protein | Vibrio vulnificus | intermediate 1 | 137 | 1.09 | 125 | pH 8, 22 °C | PMID 25431972 | Open record: COG3236-RibA fusion protein, intermediate 1 |
| COG3236-RibA fusion protein | Vibrio vulnificus | intermediate 2 | 0.07 | 0.51 | 0.13 | pH 8, 22 °C | PMID 25431972 | Open record: COG3236-RibA fusion protein, intermediate 2 |
| GTP cyclohydrolase II homologue SCO 1441 | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.042 | 0.063 | 0.67 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 1441, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 1441variant Y326F | Streptomyces coelicolor | guanosine 5'-triphosphate | 3.3 × 10⁻⁴ | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 1441 variant Y326F, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 1441variant Y326M | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.00135 | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 1441 variant Y326M, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687 | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.057 | 0.024 | 2.3 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687variant D127A | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.022 | 0.085 | 0.27 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687 variant D127A, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687variant G209D | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.047 | 0.23 | 0.2 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687 variant G209D, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687variant R83H | Streptomyces coelicolor | guanosine 5'-triphosphate | 3.3 × 10⁻⁴ | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687 variant R83H, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687variant Y123F | Streptomyces coelicolor | guanosine 5'-triphosphate | 8.8 × 10⁻⁴ | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687 variant Y123F, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687variant Y123M | Streptomyces coelicolor | guanosine 5'-triphosphateN-terminally His6-tagged (pET 28); Ni-affinity purified | 0.063 | 0.092 | 0.68 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687 variant Y123M, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 2687variant Y123M | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.097 | 0.048 | 2 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 2687 variant Y123M, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655 | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.12 | 0.056 | 2.2 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120A | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.012 | 0.059 | 0.2 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120A, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120C | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.018 | 0.067 | 0.27 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120C, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120D | Streptomyces coelicolor | guanosine 5'-triphosphate | 1.2 × 10⁻⁴ | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120D, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120E | Streptomyces coelicolor | guanosine 5'-triphosphate | 8.8 × 10⁻⁴ | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120E, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120F | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.013 | 0.019 | 0.68 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120F, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120G | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.0158 | 0.19 | 0.083 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120G, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120H | Streptomyces coelicolor | guanosine 5'-triphosphate | — | 0.05 | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120H, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120I | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.022 | 0.015 | 1.45 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120I, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120K | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.003 | 0.0089 | 0.33 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120K, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120N | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.03 | 0.067 | 0.45 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120N, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120Q | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.033 | 0.011 | 3 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120Q, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120S | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.023 | 0.033 | 0.67 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120S, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120T | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.0057 | 0.15 | 0.033 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120T, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120W | Streptomyces coelicolor | guanosine 5'-triphosphate | 5 × 10⁻⁴ | — | — | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120W, guanosine 5'-triphosphate |
| GTP cyclohydrolase II homologue SCO 6655variant M120Y | Streptomyces coelicolor | guanosine 5'-triphosphate | 0.023 | 0.008 | 3.2 | pH 8 | PMID 18281960 | Open record: GTP cyclohydrolase II homologue SCO 6655 variant M120Y, guanosine 5'-triphosphate |