EC 3.6.1.1: inorganic diphosphatase
HydrolasesOpen in Browse
CatLog read 59 records for EC 3.6.1.1 from 7 papers, for 17 organisms. Names in these papers: PfPPase (soluble inorganic pyrophosphatase), inorganic pyrophosphatase (PfPPase), MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), family II soluble inorganic pyrophosphatase (S.g-PPase) and 10 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 191 records for EC 3.6.1.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.1 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Structural and Biochemical Characterization of Apicomplexan Inorganic Pyrophosphatases | Plasmodium falciparum | 15 |
| doi:10.1016/j.molcatb.2013.09.011 | Pyrococcus furiosus | 13 |
| Thermotoga maritima MazG protein has both nucleoside triphosphate pyrophosphohydrolase and pyrophosphatase activities | Thermotoga maritima | 8 |
| A novel subfamily of monomeric inorganic pyrophosphatases in photosynthetic eukaryotes | Chlamydomonas reinhardtii, Cyanidium caldarium and 4 more | 7 |
| Comparative biochemical and functional studies of family I soluble inorganic pyrophosphatases from photosynthetic bacteria | Anabaena sp. PCC 7120, Pseudanabaena sp. PCC 6903 and 4 more | 7 |
| Isoleucine 259 and isoleucine 260 residues in Streptococcus gordonii soluble inorganic pyrophosphatase play an important role in enzyme activity | Streptococcus gordonii | 6 |
| μ₃-Oxo nucleophile formation enables efficient SN2 hydrolysis at the trinuclear metal center in inorganic pyrophosphatase | Shewanella sp. AS-11 | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| chloroplastic sPPase (soluble inorganic pyrophosphatase) | Spinacia oleracea | dimagnesium diphosphate | 102.5 | 0.0294 | 3.49 × 10³ calc. | PMID 16313235 | Open record: chloroplastic sPPase (soluble inorganic pyrophosphatase), dimagnesium diphosphate | |
| Cp-sPPase (cyanellar soluble inorganic pyrophosphatase) | Cyanophora paradoxa | dimagnesium diphosphate | 208.5 | 0.0324 | 6.44 × 10³ calc. | PMID 16313235 | Open record: Cp-sPPase (cyanellar soluble inorganic pyrophosphatase), dimagnesium diphosphate | |
| Cr-sPPase I (chloroplastic soluble inorganic pyrophosphatase I) | Chlamydomonas reinhardtii | dimagnesium diphosphate | 314.6 | 0.0105 | 3.00 × 10⁴ calc. | PMID 16313235 | Open record: Cr-sPPase I (chloroplastic soluble inorganic pyrophosphatase I), dimagnesium diphosphate | |
| Cr-sPPase II (mitochondrial soluble inorganic pyrophosphatase II) | Chlamydomonas reinhardtii | dimagnesium diphosphate | 334.6 | 0.0652 | 5.13 × 10³ calc. | PMID 16313235 | Open record: Cr-sPPase II (mitochondrial soluble inorganic pyrophosphatase II), dimagnesium diphosphate | |
| Family II inorganic pyrophosphatase (ShPPase) | Shewanella sp. AS-11 | potassium pyrophosphate | 99.8 | 0.079 | 1.26 × 10³ | pH 7.5, 25 °C | PMID 41927744 | Open record: Family II inorganic pyrophosphatase (ShPPase), potassium pyrophosphate |
| Family II inorganic pyrophosphatase (ShPPase)variant D14A | Shewanella sp. AS-11 | potassium pyrophosphate | 0.019 | 0.179 | 0.11 | pH 7.5, 25 °C | PMID 41927744 | Open record: Family II inorganic pyrophosphatase (ShPPase) variant D14A, potassium pyrophosphate |
| Family II inorganic pyrophosphatase (ShPPase)variant D14N | Shewanella sp. AS-11 | potassium pyrophosphate | 0.034 | 0.1 | 0.34 | pH 7.5, 25 °C | PMID 41927744 | Open record: Family II inorganic pyrophosphatase (ShPPase) variant D14N, potassium pyrophosphate |
| family II soluble inorganic pyrophosphatase (S.g-PPase)variant I259D | Streptococcus gordonii | inorganic pyrophosphate | 11 | 0.163 | 67 | pH 9, 25 °C | PMID 21450519 | Open record: family II soluble inorganic pyrophosphatase (S.g-PPase) variant I259D, inorganic pyrophosphate |
| family II soluble inorganic pyrophosphatase (S.g-PPase)variant I259E | Streptococcus gordonii | inorganic pyrophosphate | 48 | 0.248 | 190 | pH 9, 25 °C | PMID 21450519 | Open record: family II soluble inorganic pyrophosphatase (S.g-PPase) variant I259E, inorganic pyrophosphate |
| family II soluble inorganic pyrophosphatase (S.g-PPase)variant I259V | Streptococcus gordonii | inorganic pyrophosphate | 4.42 × 10³ | 0.055 | 8 × 10⁴ | pH 9, 25 °C | PMID 21450519 | Open record: family II soluble inorganic pyrophosphatase (S.g-PPase) variant I259V, inorganic pyrophosphate |
| family II soluble inorganic pyrophosphatase (S.g-PPase)variant I260D | Streptococcus gordonii | inorganic pyrophosphate | 560 | 0.041 | 1.4 × 10⁴ | pH 9, 25 °C | PMID 21450519 | Open record: family II soluble inorganic pyrophosphatase (S.g-PPase) variant I260D, inorganic pyrophosphate |
| family II soluble inorganic pyrophosphatase (S.g-PPase)variant I260E | Streptococcus gordonii | inorganic pyrophosphate | 570 | 0.054 | 1.1 × 10⁴ | pH 9, 25 °C | PMID 21450519 | Open record: family II soluble inorganic pyrophosphatase (S.g-PPase) variant I260E, inorganic pyrophosphate |
| family II soluble inorganic pyrophosphatase (S.g-PPase)variant I260V | Streptococcus gordonii | inorganic pyrophosphate | 6.48 × 10³ | 0.054 | 1.2 × 10⁵ | pH 9, 25 °C | PMID 21450519 | Open record: family II soluble inorganic pyrophosphatase (S.g-PPase) variant I260V, inorganic pyrophosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | adenosine-5'-diphosphate | 0.328 | 4.43 | 0.074 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), adenosine-5'-diphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | adenosine-5'-triphosphate | 1.528 | 4.13 | 0.37 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), adenosine-5'-triphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | cytidine-5'-diphosphate | 0.855 | 3.12 | 0.273 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), cytidine-5'-diphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | cytidine-5'-triphosphate | 1.57 | 3.61 | 0.435 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), cytidine-5'-triphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | guanosine-5'-diphosphate | 0.665 | 3.56 | 0.1867 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), guanosine-5'-diphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | guanosine-5'-triphosphate | 1.528 | 3.63 | 0.42 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), guanosine-5'-triphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | inosine-5'-diphosphate | 0.955 | 3.47 | 0.275 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), inosine-5'-diphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | inosine-5'-triphosphate | 1.93 | 5.01 | 0.387 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), inosine-5'-triphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | pyrophosphate | 20.5 | 0.17 | 118.3 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), pyrophosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | tripolyphosphate | 3.77 | 1.37 | 2.73 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), tripolyphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | uridine-5'-diphosphate | 0.458 | 3.32 | 0.138 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), uridine-5'-diphosphate |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | uridine-5'-diphosphate glucose | 0.495 | 6.09 | 0.0812 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), uridine-5'-diphosphate glucose |
| inorganic pyrophosphatase (PfPPase) | Pyrococcus furiosus | uridine-5'-triphosphate | 1.652 | 11.8 | 0.14 | pH 10.5, 95 °C | doi:10.1016/j.molcatb.2013.09.011 | Open record: inorganic pyrophosphatase (PfPPase), uridine-5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | 2'-deoxyadenosine 5'-triphosphate | 1.12 | 3.2 | 0.348 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), 2'-deoxyadenosine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | 2'-deoxycytidine 5'-triphosphate | 0.993 | 1.7 | 0.572 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), 2'-deoxycytidine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | 2'-deoxyguanosine 5'-triphosphate | 0.943 | 1 | 0.933 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), 2'-deoxyguanosine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | adenosine 5'-triphosphate | 0.197 | 1 | 0.198 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), adenosine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | cytidine 5'-triphosphate | 0.107 | 0.4 | 0.298 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), cytidine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | guanosine 5'-triphosphate | 0.69 | 1 | 0.677 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), guanosine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | thymidine 5'-triphosphate | 0.645 | 1.5 | 0.442 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), thymidine 5'-triphosphate |
| MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG) | Thermotoga maritima | uridine 5'-triphosphate | 0.177 | 1.1 | 0.163 | pH 8, 70 °C | PMID 12657645 | Open record: MazG nucleoside triphosphate pyrophosphohydrolase (Tm-MazG), uridine 5'-triphosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | adenosine 5'-triphosphate1 mM Zn2+ as divalent cation cofactor | 6.3 | 0.064 | 90 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), adenosine 5'-triphosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | adenosine 5'-triphosphate1 mM Co2+ as divalent cation cofactor | 2.8 | 0.096 | 20 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), adenosine 5'-triphosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | adenosine 5'-triphosphate1 mM Mn2+ as divalent cation cofactor | 0.8 | 0.18 | 8 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), adenosine 5'-triphosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | inorganic pyrophosphate1 mM Zn2+ as divalent cation cofactor | 8.3 | 0.0226 | 367 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | inorganic pyrophosphate1 mM Co2+ as divalent cation cofactor | 24.3 | 0.0194 | 1.36 × 10³ | pH 7.6, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | inorganic pyrophosphate1 mM Mn2+ as divalent cation cofactor | 6.3 | 0.0928 | 67 | pH 7.6, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | inorganic pyrophosphateMg2+ (3 mM stated in Results for the wild-type PPi kcat) | 266 | 0.01 | 2.66 × 10⁴ | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | triphosphate (tripolyphosphate) | 26.3 | 0.0016 | 1.6 × 10⁴ | pH 7, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), triphosphate (tripolyphosphate) |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | triphosphate (tripolyphosphate) | 9.6 | 0.0126 | 7.6 × 10³ | pH 7.4, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), triphosphate (tripolyphosphate) |
| PfPPase (soluble inorganic pyrophosphatase) | Plasmodium falciparum | triphosphate (tripolyphosphate) | 1.6 | 0.0085 | 180 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase), triphosphate (tripolyphosphate) |
| PfPPase (soluble inorganic pyrophosphatase)variant D198N | Plasmodium falciparum | inorganic pyrophosphate | 25.8 | 0.0426 | 1.65 × 10³ | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase) variant D198N, inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase)variant D203N | Plasmodium falciparum | inorganic pyrophosphate | 0.53 | 0.0538 | 9.85 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase) variant D203N, inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase)variant D235N | Plasmodium falciparum | inorganic pyrophosphate | 52.5 | 0.0457 | 1.16 × 10³ | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase) variant D235N, inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase)variant K136R | Plasmodium falciparum | inorganic pyrophosphate | 21.8 | 0.4028 | 53 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase) variant K136R, inorganic pyrophosphate |
| PfPPase (soluble inorganic pyrophosphatase)variant R158K | Plasmodium falciparum | inorganic pyrophosphate | 60.4 | 0.0642 | 940 | pH 7.2, 37 °C | PMID 28701714 | Open record: PfPPase (soluble inorganic pyrophosphatase) variant R158K, inorganic pyrophosphate |
| plastidic sPPase (soluble inorganic pyrophosphatase) | Cyanidium caldarium | dimagnesium diphosphate | 184.5 | 0.0105 | 1.76 × 10⁴ calc. | PMID 16313235 | Open record: plastidic sPPase (soluble inorganic pyrophosphatase), dimagnesium diphosphate | |
| plastidic sPPase (soluble inorganic pyrophosphatase) | Euglena gracilis | dimagnesium diphosphate | 280 | 0.0324 | 8.6 × 10³ calc. | PMID 16313235 | Open record: plastidic sPPase (soluble inorganic pyrophosphatase), dimagnesium diphosphate | |
| plastidic sPPase (soluble inorganic pyrophosphatase) | Ochromonas danica | dimagnesium diphosphate | 204.5 | 0.0292 | 7.00 × 10³ calc. | PMID 16313235 | Open record: plastidic sPPase (soluble inorganic pyrophosphatase), dimagnesium diphosphate | |
| soluble inorganic pyrophosphatase | Rhodopseudomonas palustris | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) | 800 | 0.0301 | 2.7 × 10⁴ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase, dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |
| soluble inorganic pyrophosphatase | Rhodopseudomonas viridis | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) | 750 | 0.0274 | 2.7 × 10⁴ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase, dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |
| soluble inorganic pyrophosphatase | Rhodospirillum rubrum | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) | 750 | 0.0252 | 3.0 × 10⁴ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase, dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |
| soluble inorganic pyrophosphatase (A. 7120 sPPase) | Anabaena sp. PCC 7120 | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) | 850 | 0.003 | 2.8 × 10⁵ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase (A. 7120 sPPase), dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |
| soluble inorganic pyrophosphatase (P. 6903 sPPase) | Pseudanabaena sp. PCC 6903 | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) | 850 | 0.0029 | 2.9 × 10⁵ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase (P. 6903 sPPase), dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |
| soluble inorganic pyrophosphatase (S. 6803 sPPase) | Synechocystis sp. PCC 6803 | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate)native; purified from Synechocystis sp. PCC 6803 cells | 916 | 0.0028 | 3.3 × 10⁵ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase (S. 6803 sPPase), dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |
| soluble inorganic pyrophosphatase (S. 6803 sPPase) | Synechocystis sp. PCC 6803 | dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate)recombinant | 800 | 0.0031 | 2.6 × 10⁵ calc. | pH 7.5, 22 °C | PMID 17635582 | Open record: soluble inorganic pyrophosphatase (S. 6803 sPPase), dimagnesium diphosphate (Mg2+ complex of inorganic pyrophosphate) |