EC 3.6.1.12: dCTP diphosphatase
HydrolasesOpen in Browse
CatLog read 30 records for EC 3.6.1.12 from 3 papers, for 2 organisms. Names in these papers: RS21-C6 (dCTP pyrophosphohydrolase), DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), DCTPP1 (dCTP pyrophosphatase 1).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 8 records for EC 3.6.1.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.12 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine | Mus musculus | 13 |
| The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells | Homo sapiens | 10 |
| Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation | Homo sapiens | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | 5-Br-dCTP | 0.5047 | 0.1089 | 4.634 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), 5-Br-dCTP | |
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | 5-I-dCTP | 0.4305 | 0.0944 | 4.560 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), 5-I-dCTP | |
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | 5-Methyl-dCTP | 0.3617 | 0.08503 | 4.25 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), 5-Methyl-dCTP | |
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | dATP | 0.1415 | 0.2928 | 0.4832 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), dATP | |
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | dCTP | 0.367 | 0.1523 | 2.410 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), dCTP | |
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | dTTP | 0.1082 | 0.1961 | 0.5515 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), dTTP | |
| DCTPP1 (dCTP pyrophosphatase 1) | Homo sapiens | dUTP | 0.081 | 0.2406 | 0.3367 | PMID 26075750 | Open record: DCTPP1 (dCTP pyrophosphatase 1), dUTP | |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 2'-deoxyadenosine 5'-triphosphate | 2 | 0.0793 | 25 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 2'-deoxyadenosine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 2'-deoxycytidine 5'-triphosphate | 5.7 | — | — | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 2'-deoxycytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 2'-deoxyuridine 5'-triphosphate | 1.3 | 0.0759 | 17 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 2'-deoxyuridine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 5-bromo-2'-deoxycytidine 5'-triphosphate | 9.3 | 0.0365 | 256 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 5-bromo-2'-deoxycytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 5-formyl-2'-deoxycytidine 5'-triphosphate | 3 | 0.0092 | 322 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 5-formyl-2'-deoxycytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 5-hydroxymethyl-2'-deoxycytidine 5'-triphosphate | 5.6 | 0.0629 | 90 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 5-hydroxymethyl-2'-deoxycytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 5-iodo-2'-deoxycytidine 5'-triphosphate | 6.2 | 0.0168 | 371 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 5-iodo-2'-deoxycytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | 5-methyl-2'-deoxycytidine 5'-triphosphate | 4.8 | 0.0333 | 143 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), 5-methyl-2'-deoxycytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | cytidine 5'-triphosphate | 1.3 | 0.1429 | 9 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), cytidine 5'-triphosphate |
| DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA) | Homo sapiens | thymidine 5'-triphosphate | 1.8 | 0.065 | 28 | pH 8, 25 °C | PMID 24467396 | Open record: DCTPP1 (dCTP pyrophosphatase 1; XTP3-TPA), thymidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 2'-deoxyadenosine 5'-triphosphate | 0.53 | 0.118 | 4.49 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 2'-deoxyadenosine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 2'-deoxycytidine 5'-triphosphate | 1.37 | 0.0441 | 31.1 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 2'-deoxycytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 2'-deoxyuridine 5'-triphosphate | 0.76 | 0.484 | 1.57 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 2'-deoxyuridine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 2-chloro-2'-deoxyadenosine 5'-triphosphate | 1.57 | 0.107 | 14.7 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 2-chloro-2'-deoxyadenosine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | 1.39 | 0.169 | 8.22 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 2-hydroxy-2'-deoxyadenosine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 5-bromo-2'-deoxycytidine 5'-triphosphate | 1.49 | 0.0217 | 68.7 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 5-bromo-2'-deoxycytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 5-chloro-2'-deoxycytidine 5'-triphosphate | 1.5 | 0.05 | 30 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 5-chloro-2'-deoxycytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 5-fluoro-2'-deoxyuridine 5'-triphosphate | 0.58 | 0.304 | 1.9 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 5-fluoro-2'-deoxyuridine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 5-hydroxy-2'-deoxycytidine 5'-triphosphate | 0.87 | 0.164 | 5.3 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 5-hydroxy-2'-deoxycytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 5-iodo-2'-deoxycytidine 5'-triphosphate | 0.94 | 0.0039 | 241 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 5-iodo-2'-deoxycytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | 5-methyl-2'-deoxycytidine 5'-triphosphate | 1.33 | 0.0485 | 27.4 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), 5-methyl-2'-deoxycytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | cytidine 5'-triphosphate | 0.31 | 0.529 | 0.156 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), cytidine 5'-triphosphate |
| RS21-C6 (dCTP pyrophosphohydrolase) | Mus musculus | thymidine 5'-triphosphate | 0.76 | 0.407 | 1.87 | pH 8, 30 °C | PMID 19220460 | Open record: RS21-C6 (dCTP pyrophosphohydrolase), thymidine 5'-triphosphate |