CatLogenzyme kinetics catalog

EC 3.6.1.60: diadenosine hexaphosphate hydrolase (AMP-forming)

HydrolasesOpen in Browse

CatLog read 16 records for EC 3.6.1.60 from 3 papers, for 2 organisms. Names in these papers: hAps1, hAps1-39N, hAps2, hDIPP3α and 2 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 9 records for EC 3.6.1.60 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.60 in Browse.

Papers

PaperOrganismsRecords
Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolasesHomo sapiens9
An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolaseHomo sapiens6
The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping…Saccharomyces cerevisiae1

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
hAps1Homo sapiensdiadenosine 5',5'''-hexaphosphate0.170.01313.1pH 7.6, 37 °CPMID 12121577Open
hAps1Homo sapiensdiadenosine 5',5'''-pentaphosphate0.40.03710.8pH 7.6, 37 °CPMID 12121577Open
hAps1Homo sapiensdiphosphoinositol pentakisphosphate0.20.00450pH 7.6PMID 12121577Open
hAps1-39NHomo sapiensdiadenosine 5',5'''-hexaphosphate0.160.01114.5pH 7.6, 37 °CPMID 12121577Open
hAps1-39NHomo sapiensdiadenosine 5',5'''-pentaphosphate0.40.058pH 7.6, 37 °CPMID 12121577Open
hAps1-39NHomo sapiensdiphosphoinositol pentakisphosphate0.093 × 10⁻⁴290pH 7.6PMID 12121577Open
hAps2Homo sapiensdiadenosine 5',5'''-hexaphosphate0.20.01910.5pH 7.6, 37 °CPMID 12121577Open
hAps2Homo sapiensdiadenosine 5',5'''-pentaphosphate0.80.0516pH 7.6, 37 °CPMID 12121577Open
hAps2Homo sapiensdiphosphoinositol pentakisphosphate0.140.0013110pH 7.6PMID 12121577Open
hDIPP3αHomo sapiensbis-diphosphoinositol tetrakisphosphate——180pH 7.2, 37 °CPMID 12105228Open
hDIPP3αHomo sapiensdiadenosine 5',5'''-P1,P6-hexaphosphate0.580.03318pH 7.6, 37 °CPMID 12105228Open
hDIPP3αHomo sapiensdiphosphoinositol pentakisphosphate0.168.8 × 10⁻⁵1.8 × 10³pH 7.2, 37 °CPMID 12105228Open
hDIPP3βHomo sapiensbis-diphosphoinositol tetrakisphosphate——490pH 7.2, 37 °CPMID 12105228Open
hDIPP3βHomo sapiensdiadenosine 5',5'''-P1,P6-hexaphosphate0.950.04322pH 7.6, 37 °CPMID 12105228Open
hDIPP3βHomo sapiensdiphosphoinositol pentakisphosphate0.225.3 × 10⁻⁵4.2 × 10³pH 7.2, 37 °CPMID 12105228Open
YOR163w (Ap6A hydrolase)Saccharomyces cerevisiaediphosphoinositol pentakisphosphate0.063.1 × 10⁻⁵2 × 10³pH 7.2PMID 10419486Open