EC 3.6.1.65: (d)CTP diphosphatase
HydrolasesOpen in Browse
CatLog read 15 records for EC 3.6.1.65 from 2 papers, for 1 organism. Names in these papers: Orf135 protein, Orf135 (Nudix hydrolase, CTPase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 4 records for EC 3.6.1.65 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.65 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Amino acid residues involved in substrate recognition of the Escherichia coli Orf135 protein | Escherichia coli | 12 |
| Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP | Escherichia coli | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| Orf135 (Nudix hydrolase, CTPase) | Escherichia coli | 2'-deoxycytidine 5'-triphosphate | 14.3 | 0.767 | 18 | pH 9, 37 °C | PMID 11053429 | Open record: Orf135 (Nudix hydrolase, CTPase), 2'-deoxycytidine 5'-triphosphate |
| Orf135 (Nudix hydrolase, CTPase) | Escherichia coli | 5-methyl-2'-deoxycytidine 5'-triphosphate | 51.7 | 0.172 | 301 | pH 9, 37 °C | PMID 11053429 | Open record: Orf135 (Nudix hydrolase, CTPase), 5-methyl-2'-deoxycytidine 5'-triphosphate |
| Orf135 (Nudix hydrolase, CTPase) | Escherichia coli | cytidine 5'-triphosphate | 25.8 | 0.551 | 47 | pH 9, 37 °C | PMID 11053429 | Open record: Orf135 (Nudix hydrolase, CTPase), cytidine 5'-triphosphate |
| Orf135 proteinvariant D118A | Escherichia coli | 5-methyl-2'-deoxycytidine 5'-triphosphate | 9.1 | 0.24 | 38 | PMID 15823026 | Open record: Orf135 protein variant D118A, 5-methyl-2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant D118A | Escherichia coli | 8-hydroxy-2'-deoxyguanosine 5'-triphosphate | 2.7 | 0.19 | 14 | PMID 15823026 | Open record: Orf135 protein variant D118A, 8-hydroxy-2'-deoxyguanosine 5'-triphosphate | |
| Orf135 proteinvariant D118E | Escherichia coli | 2'-deoxycytidine 5'-triphosphate | 2.1 | 0.93 | 2.3 | PMID 15823026 | Open record: Orf135 protein variant D118E, 2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant D118E | Escherichia coli | 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | 0.45 | 0.0055 | 82 | PMID 15823026 | Open record: Orf135 protein variant D118E, 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | |
| Orf135 proteinvariant D118E | Escherichia coli | 5-methyl-2'-deoxycytidine 5'-triphosphate | 6.5 | 0.0069 | 944 | PMID 15823026 | Open record: Orf135 protein variant D118E, 5-methyl-2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant D118N | Escherichia coli | 2'-deoxycytidine 5'-triphosphate | 2.7 | 0.77 | 3.5 | PMID 15823026 | Open record: Orf135 protein variant D118N, 2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant D118N | Escherichia coli | 5-methyl-2'-deoxycytidine 5'-triphosphate | 7.7 | 0.0057 | 1.4 × 10³ | PMID 15823026 | Open record: Orf135 protein variant D118N, 5-methyl-2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant E33A | Escherichia coli | 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | 1.42 | 0.067 | 21 | PMID 15823026 | Open record: Orf135 protein variant E33A, 2-hydroxy-2'-deoxyadenosine 5'-triphosphate | |
| Orf135 proteinvariant E33A | Escherichia coli | 5-methyl-2'-deoxycytidine 5'-triphosphate | 2.8 | 0.22 | 13 | PMID 15823026 | Open record: Orf135 protein variant E33A, 5-methyl-2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant R72A | Escherichia coli | 2'-deoxycytidine 5'-triphosphate | 8.8 | 0.65 | 14 | PMID 15823026 | Open record: Orf135 protein variant R72A, 2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant R72A | Escherichia coli | 5-methyl-2'-deoxycytidine 5'-triphosphate | 11 | 0.015 | 780 | PMID 15823026 | Open record: Orf135 protein variant R72A, 5-methyl-2'-deoxycytidine 5'-triphosphate | |
| Orf135 proteinvariant R72A | Escherichia coli | 8-hydroxy-2'-deoxyguanosine 5'-triphosphate | 1.4 | 0.31 | 4.6 | PMID 15823026 | Open record: Orf135 protein variant R72A, 8-hydroxy-2'-deoxyguanosine 5'-triphosphate |