EC 3.6.1.72: DNA-3'-diphospho-5'-guanosine diphosphatase
HydrolasesOpen in Browse
CatLog read 4 records for EC 3.6.1.72 from 1 paper, for 1 organism. Names in these papers: Aprataxin.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Aprataxin forms a discrete branch in the HIT (histidine triad) superfamily of proteins with both DNA/RNA binding and nucleotide hydrolase activities | Homo sapiens | 4 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| Aprataxin | Homo sapiens | adenosine 5'-monophosphoramidate | 0.0195 | 0.8375 | 0.0233 calc. | pH 7, 30 °C | PMID 16547001 | Open record: Aprataxin, adenosine 5'-monophosphoramidate |
| Aprataxin | Homo sapiens | diadenosine tetraphosphate1 µM Aprataxin; self-cleaved; one extra C-terminal glycine | 0.0115 | 0.018 | 0.64 calc. | pH 7, 30 °C | PMID 16547001 | Open record: Aprataxin, diadenosine tetraphosphate |
| Aprataxin | Homo sapiens | diadenosine tetraphosphateMichaelis fit over 0.02-0.6 mM substrate (Fig. 8C) | 0.0171 | — | — | pH 7, 30 °C | PMID 16547001 | Open record: Aprataxin, diadenosine tetraphosphate |
| AprataxinN-terminal truncation (ΔFHA) | Homo sapiens | diadenosine tetraphosphate | 0.0176 | — | — | pH 7, 30 °C | PMID 16547001 | Open record: Aprataxin N-terminal truncation (ΔFHA), diadenosine tetraphosphate |