EC 3.6.1.77: coenzyme A diphosphatase

HydrolasesOpen in Browse

CatLog read 24 records for EC 3.6.1.77 from 2 papers, for 1 organism. Names in these papers: Nudt19 (CoA diphosphohydrolase, RP2p), Nudt7 (CoA diphosphohydrolase), NUDT7α.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 6 records for EC 3.6.1.77 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.6.1.77 in Browse.

Papers

Papers with records for EC 3.6.1.77
Paper	Organisms	Records
Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform	Mus musculus	19
The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives	Mus musculus	5

Records

Records for EC 3.6.1.77 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
Nudt19 (CoA diphosphohydrolase, RP2p)	Mus musculus	coenzyme A	4.73	0.3	16 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p), coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)Nudt19-7-CB (chimera: Nudt19 with the Nudt7 CoA box)	Mus musculus	coenzyme A	8.3 × 10⁻⁴	1.134	7.3 × 10⁻⁴ calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) Nudt19-7-CB (chimera: Nudt19 with the Nudt7 CoA box), coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant D53A	Mus musculus	coenzyme A	5.38	0.434	12.4 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant D53A, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant E115A	Mus musculus	coenzyme A	0.0027	1.019	0.0026 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant E115A, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant F40A	Mus musculus	coenzyme A	3.5	1.053	3.3 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant F40A, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant L41A	Mus musculus	coenzyme A	1.68	1.25	1.35 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant L41A, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant R189A	Mus musculus	coenzyme A	1.97	1.193	1.65 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant R189A, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant R189M	Mus musculus	coenzyme A	2.95	0.455	6.48 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant R189M, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant R34M	Mus musculus	coenzyme A	0.002	0.68	0.0029 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant R34M, coenzyme A
Nudt19 (CoA diphosphohydrolase, RP2p)variant R39A	Mus musculus	coenzyme A	1.52	0.511	3.00 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt19 (CoA diphosphohydrolase, RP2p) variant R39A, coenzyme A
Nudt7 (CoA diphosphohydrolase)	Mus musculus	coenzyme A	2.08	0.283	7.36 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase), coenzyme A
Nudt7 (CoA diphosphohydrolase)Nudt7-19-CB (chimera: Nudt7 with the Nudt19 CoA box)	Mus musculus	coenzyme A	0.0047	1.362	0.0034 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) Nudt7-19-CB (chimera: Nudt7 with the Nudt19 CoA box), coenzyme A
Nudt7 (CoA diphosphohydrolase)Nudt7-19-NB (chimera: Nudt7 with the Nudt19 Nudix box)	Mus musculus	coenzyme A	0.0108	0.836	0.0130 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) Nudt7-19-NB (chimera: Nudt7 with the Nudt19 Nudix box), coenzyme A
Nudt7 (CoA diphosphohydrolase)variant D79A	Mus musculus	coenzyme A	2.65	0.334	7.93 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) variant D79A, coenzyme A
Nudt7 (CoA diphosphohydrolase)variant E95A	Mus musculus	coenzyme A	0.17	0.444	0.38 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) variant E95A, coenzyme A
Nudt7 (CoA diphosphohydrolase)variant K65A	Mus musculus	coenzyme A	7.72	0.958	8.05 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) variant K65A, coenzyme A
Nudt7 (CoA diphosphohydrolase)variant R60M	Mus musculus	coenzyme A	0.0092	1.01	0.0091 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) variant R60M, coenzyme A
Nudt7 (CoA diphosphohydrolase)variant R66A	Mus musculus	coenzyme A	3.7	3.069	1.2 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) variant R66A, coenzyme A
Nudt7 (CoA diphosphohydrolase)variant R66M	Mus musculus	coenzyme A	2.78	0.496	5.61 calc.	pH 8, 37 °C	PMID 29378847	Open record: Nudt7 (CoA diphosphohydrolase) variant R66M, coenzyme A
NUDT7α	Mus musculus	3′-dephospho-coenzyme A	1.6	0.48	3.3	pH 7.5, 37 °C	PMID 11415433	Open record: NUDT7α, 3′-dephospho-coenzyme A
NUDT7α	Mus musculus	acetyl coenzyme A	5.5	0.43	12.6	pH 7.5, 37 °C	PMID 11415433	Open record: NUDT7α, acetyl coenzyme A
NUDT7α	Mus musculus	coenzyme A	3.8	0.24	16	pH 7.5, 37 °C	PMID 11415433	Open record: NUDT7α, coenzyme A
NUDT7α	Mus musculus	coenzyme A disulfide (oxidized CoA)	2.1	0.235	9	pH 7.5, 37 °C	PMID 11415433	Open record: NUDT7α, coenzyme A disulfide (oxidized CoA)
NUDT7α	Mus musculus	succinyl coenzyme A	3	0.33	9	pH 7.5, 37 °C	PMID 11415433	Open record: NUDT7α, succinyl coenzyme A