EC 3.7.1.17: 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
HydrolasesOpen in Browse
CatLog read 3 records for EC 3.7.1.17 from 1 paper, for 1 organism. Names in these papers: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 2 records for EC 3.7.1.17 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 3.7.1.17 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism | Mycobacterium tuberculosis | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD) | Mycobacterium tuberculosis | 2-hydroxy-5-methyl-8-(7a-methyl-1,5-dioxooctahydro-1H-inden-4-yl)-6-oxoocta-2,4-dienoic acid | 0.55 | 0.017 | 33 | pH 7.5, 25 °C | PMID 19875455 | Open record: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD), 2-hydroxy-5-methyl-8-(7a-methyl-1,5-dioxooctahydro-1H-inden-4-yl)-6-oxoocta-2,4-dienoic acid |
| 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD) | Mycobacterium tuberculosis | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid | 0.066 | 0.008 | 9 | pH 7.5, 25 °C | PMID 19875455 | Open record: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD), 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid |
| 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD) | Mycobacterium tuberculosis | 8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid | 0.33 | 0.31 | 1.06 | pH 7.5, 25 °C | PMID 19875455 | Open record: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (HsaD), 8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid |