EC 4.1.1.28: aromatic-L-amino-acid decarboxylase
LyasesOpen in Browse
CatLog read 10 records for EC 4.1.1.28 from 3 papers, for 3 organisms. Names in these papers: aromatic L-amino acid decarboxylase (AADC-BA), dopa decarboxylase, DOPA decarboxylase (DDC).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 52 records for EC 4.1.1.28 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.1.28 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Biochemical characterization and synthetic application of aromatic L-amino acid decarboxylase from Bacillus atrophaeus | Bacillus atrophaeus | 5 |
| Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions | Sus scrofa | 4 |
| Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson's disease | Homo sapiens | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| aromatic L-amino acid decarboxylase (AADC-BA) | Bacillus atrophaeus | L-phenylalanine | 7 | 10 | 0.68 | pH 7, 30 °C | PMID 33713143 | Open record: aromatic L-amino acid decarboxylase (AADC-BA), L-phenylalanine |
| aromatic L-amino acid decarboxylase (AADC-BA) | Bacillus atrophaeus | L-phenylalanine | 7.4 | 7.2 | 1 | pH 7, 37 °C | PMID 33713143 | Open record: aromatic L-amino acid decarboxylase (AADC-BA), L-phenylalanine |
| aromatic L-amino acid decarboxylase (AADC-BA) | Bacillus atrophaeus | L-phenylalanine | 7.4 | 6.9 | 1.1 | pH 7, 45 °C | PMID 33713143 | Open record: aromatic L-amino acid decarboxylase (AADC-BA), L-phenylalanine |
| aromatic L-amino acid decarboxylase (AADC-BA) | Bacillus atrophaeus | L-phenylalanine | 4.3 | 5.4 | 0.8 | pH 7, 55 °C | PMID 33713143 | Open record: aromatic L-amino acid decarboxylase (AADC-BA), L-phenylalanine |
| aromatic L-amino acid decarboxylase (AADC-BA) | Bacillus atrophaeus | L-tryptophan | 6.7 | 0.27 | 25 | pH 7, 37 °C | PMID 33713143 | Open record: aromatic L-amino acid decarboxylase (AADC-BA), L-tryptophan |
| dopa decarboxylase | Sus scrofa | L-3,4-dihydroxyphenylalanineaerobic (atmospheric O2) | 4.26 | 0.0703 | 60.6 calc. | pH 7.5 | PMID 11085948 | Open record: dopa decarboxylase, L-3,4-dihydroxyphenylalanine |
| dopa decarboxylase | Sus scrofa | L-3,4-dihydroxyphenylalanineanaerobic (nitrogen-flushed Reacti-Vials) | 2.57 | 0.035 | 73 calc. | pH 7.5 | PMID 11085948 | Open record: dopa decarboxylase, L-3,4-dihydroxyphenylalanine |
| dopa decarboxylase | Sus scrofa | L-5-hydroxytryptophanaerobic (atmospheric O2) | 1.99 | 0.155 | 12.8 calc. | pH 7.5 | PMID 11085948 | Open record: dopa decarboxylase, L-5-hydroxytryptophan |
| dopa decarboxylase | Sus scrofa | L-5-hydroxytryptophananaerobic (nitrogen-flushed Reacti-Vials) | 0.99 | 0.038 | 26 calc. | pH 7.5 | PMID 11085948 | Open record: dopa decarboxylase, L-5-hydroxytryptophan |
| DOPA decarboxylase (DDC) | Homo sapiens | L-3,4-dihydroxyphenylalanine | 2.282 | 0.1 | 26.12 | pH 7.4 | PMID 30659181 | Open record: DOPA decarboxylase (DDC), L-3,4-dihydroxyphenylalanine |