EC 4.1.1.74: indolepyruvate decarboxylase
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CatLog read 65 records for EC 4.1.1.74 from 3 papers, for 2 organisms. Names in these papers: phenylpyruvate decarboxylase (ScPPDC), indolepyruvate decarboxylase, indolepyruvate decarboxylase (EcIPDC).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 6 records for EC 4.1.1.74 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.1.74 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae | Saccharomyces cerevisiae | 41 |
| Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate… | Enterobacter cloacae | 14 |
| Studies on structure-function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway | Enterobacter cloacae | 10 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| indolepyruvate decarboxylasevariant D29E | Enterobacter cloacae | benzoylformate | 0.01 | 0.024 | 0.4 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant D29E, benzoylformate |
| indolepyruvate decarboxylasevariant D29E | Enterobacter cloacae | pyruvate | 0.019 | 0.63 | 0.03 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant D29E, pyruvate |
| indolepyruvate decarboxylasevariant E468D | Enterobacter cloacae | 3-indolepyruvate | 0.04 | 0.0186 | 2.2 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant E468D, 3-indolepyruvate |
| indolepyruvate decarboxylasevariant E468D | Enterobacter cloacae | benzoylformate | 0.07 | 0.14 | 0.5 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant E468D, benzoylformate |
| indolepyruvate decarboxylasevariant E468D | Enterobacter cloacae | pyruvate | 0.069 | 3.16 | 0.02 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant E468D, pyruvate |
| indolepyruvate decarboxylasevariant E52D | Enterobacter cloacae | 3-indolepyruvate | 0.1 | 0.0045 | 22.2 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant E52D, 3-indolepyruvate |
| indolepyruvate decarboxylasevariant E52D | Enterobacter cloacae | benzoylformate | 0.87 | 2.72 | 0.3 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant E52D, benzoylformate |
| indolepyruvate decarboxylasevariant E52D | Enterobacter cloacae | pyruvate | 0.06 | 0.77 | 0.08 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant E52D, pyruvate |
| indolepyruvate decarboxylasevariant H115K | Enterobacter cloacae | 3-indolepyruvate | 0.31 | 0.0326 | 9.5 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant H115K, 3-indolepyruvate |
| indolepyruvate decarboxylasevariant H115K | Enterobacter cloacae | benzoylformate | 0.29 | 0.27 | 1.1 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant H115K, benzoylformate |
| indolepyruvate decarboxylasevariant H115K | Enterobacter cloacae | pyruvate | 0.016 | 3.48 | 0.004 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant H115K, pyruvate |
| indolepyruvate decarboxylasevariant Q383T | Enterobacter cloacae | 3-indolepyruvate | 2.05 | 0.024 | 85.4 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant Q383T, 3-indolepyruvate |
| indolepyruvate decarboxylasevariant Q383T | Enterobacter cloacae | benzoylformate | 2.25 | 1.71 | 1.3 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant Q383T, benzoylformate |
| indolepyruvate decarboxylasevariant Q383T | Enterobacter cloacae | pyruvate | 2.06 | 0.73 | 2.82 | pH 6.5, 30 °C | PMID 15835904 | Open record: indolepyruvate decarboxylase variant Q383T, pyruvate |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-bromophenyl)-2-oxoacetic acid | 3.2 | 0.019 | 168 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-bromophenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-chlorophenyl)-2-oxoacetic acid | 5.3 | 0.048 | 110 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-chlorophenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-ethylphenyl)-2-oxoacetic acid | 5.7 | 0.111 | 51 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-ethylphenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-fluorophenyl)-2-oxoacetic acid | 22.7 | 0.617 | 37 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-fluorophenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-methoxyphenyl)-2-oxoacetic acid | 3.5 | 1.043 | 3 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-methoxyphenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-methylphenyl)-2-oxoacetic acid | 4.5 | 0.127 | 35 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-methylphenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | 2-(4-nitrophenyl)-2-oxoacetic acid | 0.4 | 0.005 | 80 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), 2-(4-nitrophenyl)-2-oxoacetic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | benzoylformic acid | 46.4 | 1.646 | 28 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), benzoylformic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | indole-3-pyruvic acid | 3.9 | 0.02 | 199 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), indole-3-pyruvic acid |
| indolepyruvate decarboxylase (EcIPDC) | Enterobacter cloacae | pyruvic acid | 3.5 | 3.381 | 1 | pH 6.5, 30 °C | PMID 12752452 | Open record: indolepyruvate decarboxylase (EcIPDC), pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Keto-4-phenylbutanoic acid | 1.7 | 0.09 | 19 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Keto-4-phenylbutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-ketobutanoic acid | 3.9 | 7.6 | 0.52 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 3.9 | 7.6 | 0.51 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 8.8 | 0.69 | 13 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 8.8 | 0.48 | 18 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 5.2 | 2.1 | 2.5 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 2.8 | 1.7 | 1.6 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 3-Methyl-2-ketobutanoic acid | 19 | 8.5 | 2.2 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 3-Methyl-2-ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 3-Methyl-2-ketopentanoic acid | 11 | 3.1 | 3.5 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 3-Methyl-2-ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 4-Hydroxyphenylpyruvic acid | 11 | 0.09 | 125 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 4-Hydroxyphenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 4-Methyl-2-ketopentanoic acid | 10 | 0.9 | 11 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 4-Methyl-2-ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | 4-Methylthio-2-ketobutanoic acid | 7.7 | 0.64 | 12 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), 4-Methylthio-2-ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Benzoylformic acid | — | — | 0.35 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Benzoylformic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Indole-3-pyruvic acid | 5.4 | 0.03 | 200 | pH 6.5, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Indole-3-pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Indole-3-pyruvic acidkcat from a Hill fit | 5.3 | — | — | pH 6.5, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Indole-3-pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Phenylpyruvic acid | 20 | 0.1 | 200 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Phenylpyruvic acid | 20 | 0.1 | 200 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Phenylpyruvic acidkcat from a Hill fit | 22 | — | — | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Pyruvic acid | 0.34 | 9.7 | 0.035 | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC) | Saccharomyces cerevisiae | Pyruvic acid | 0.26 | 5.7 | 0.046 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC), Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant E545L | Saccharomyces cerevisiae | Indole-3-pyruvic acid | 0.14 | — | — | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant E545L, Indole-3-pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant E545L | Saccharomyces cerevisiae | Phenylpyruvic acid | 0.03 | — | — | pH 7, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant E545L, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 0.06 | 6.4 | 0.009 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 3.3 | 0.55 | 6 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 2.1 | 0.63 | 3.4 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | Phenylpyruvic acid | 0.85 | 0.8 | 1.1 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y | Saccharomyces cerevisiae | Pyruvic acid | 0.064 | 25 | 0.003 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y, Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 0.41 | 1 | 0.42 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 0.39 | 0.96 | 0.4 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | Phenylpyruvic acid | — | — | 0.03 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant I335Y/M624W | Saccharomyces cerevisiae | Pyruvic acid | — | — | 0.027 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant I335Y/M624W, Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 0.04 | 5.5 | 0.007 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 0.96 | 0.17 | 5.8 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 0.76 | 0.37 | 2.1 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | Phenylpyruvic acid | 1.2 | 0.18 | 6.7 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant M624W | Saccharomyces cerevisiae | Pyruvic acid | 0.45 | 6.4 | 0.07 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant M624W, Pyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | 2-Ketobutanoic acid | 2.2 | 7 | 0.315 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, 2-Ketobutanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | 2-Ketohexanoic acid | 1.3 | 0.46 | 2.8 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, 2-Ketohexanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | 2-Ketopentanoic acid | 2 | 0.54 | 3.7 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, 2-Ketopentanoic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | Phenylpyruvic acid | 4.8 | 0.054 | 89 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, Phenylpyruvic acid |
| phenylpyruvate decarboxylase (ScPPDC)variant Q448W | Saccharomyces cerevisiae | Pyruvic acid | 0.32 | 5.5 | 0.06 | pH 6, 30 °C | PMID 21501384 | Open record: phenylpyruvate decarboxylase (ScPPDC) variant Q448W, Pyruvic acid |