EC 4.1.2.48: low-specificity L-threonine aldolase
LyasesOpen in Browse
CatLog read 35 records for EC 4.1.2.48 from 2 papers, for 2 organisms. Names in these papers: low-specificity L-threonine aldolase (eTA), Cc-LTA (low specificity l-threonine aldolase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 60 records for EC 4.1.2.48 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.2.48 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| On the catalytic mechanism and stereospecificity of Escherichia coli L-threonine aldolase | Escherichia coli | 18 |
| doi:10.1016/j.tet.2012.05.097 | Caulobacter crescentus | 17 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| Cc-LTA (low specificity l-threonine aldolase) | Caulobacter crescentus | l-allo-Threonine | 20 | 0.69 | 29 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase), l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase) | Caulobacter crescentus | l-Threonine | 3.3 | 13.6 | 0.24 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase), l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95C | Caulobacter crescentus | l-allo-Threonine | 19 | 11 | 1.7 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95C, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95C | Caulobacter crescentus | l-Threonine | 3 | 44 | 0.068 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95C, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95H/E96G | Caulobacter crescentus | l-allo-Threonine | 8.6 | 2.9 | 3 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95H/E96G, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95H/E96G | Caulobacter crescentus | l-Threonine | 0.6 | 13 | 0.046 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95H/E96G, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95L | Caulobacter crescentus | l-allo-Threonine | 22 | 12 | 1.8 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95L, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95L | Caulobacter crescentus | l-Threonine | 3.8 | 53 | 0.072 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95L, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95M | Caulobacter crescentus | l-Threonine | 3.6 | 50 | 0.072 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95M, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95N/E96S | Caulobacter crescentus | l-allo-Threonine | 0.2 | 7.1 | 0.028 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95N/E96S, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95N/E96S | Caulobacter crescentus | l-Threonine | 0.2 | 32 | 0.0063 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95N/E96S, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95W | Caulobacter crescentus | l-allo-Threonine | 19 | 2.5 | 7.6 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95W, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95W | Caulobacter crescentus | l-Threonine | 9.6 | 44 | 0.218 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95W, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95Y | Caulobacter crescentus | l-allo-Threonine | 20 | 2.7 | 7.4 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95Y, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95Y | Caulobacter crescentus | l-Threonine | 3.5 | 63 | 0.056 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95Y, l-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95Y/E96T | Caulobacter crescentus | l-allo-Threonine | 3 | 4.4 | 0.68 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95Y/E96T, l-allo-Threonine |
| Cc-LTA (low specificity l-threonine aldolase)variant D95Y/E96T | Caulobacter crescentus | l-Threonine | — | — | 0.0016 | pH 8, 30 °C | doi:10.1016/j.tet.2012.05.097 | Open record: Cc-LTA (low specificity l-threonine aldolase) variant D95Y/E96T, l-Threonine |
| low-specificity L-threonine aldolase (eTA) | Escherichia coli | L-allo-Threonine | 3.55 | 0.24 | 14.78 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA), L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA) | Escherichia coli | L-Threonine | 1.87 | 19.4 | 0.097 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA), L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant F87A | Escherichia coli | L-allo-Threonine | 2.7 | 0.31 | 8.6 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant F87A, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant F87A | Escherichia coli | L-Threonine | 0.72 | 8.7 | 0.082 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant F87A, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant F87D | Escherichia coli | L-allo-Threonine | 1.95 | 0.41 | 4.75 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant F87D, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant F87D | Escherichia coli | L-Threonine | 0.33 | 24.9 | 0.0132 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant F87D, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H126F | Escherichia coli | L-allo-Threonine | 9.02 | 0.2 | 45.08 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H126F, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H126F | Escherichia coli | L-Threonine | 6 | 1.7 | 3.53 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H126F, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H126N | Escherichia coli | L-allo-Threonine | 7.82 | 0.96 | 8.13 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H126N, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H126N | Escherichia coli | L-Threonine | 4.37 | 61 | 0.067 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H126N, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H83F | Escherichia coli | L-allo-Threonine | 0.062 | 7 | 0.0088 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H83F, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H83F | Escherichia coli | L-Threonine | 0.02 | 7 | 0.0028 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H83F, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H83F/H126F | Escherichia coli | L-allo-Threonine | 0.028 | 7.4 | 0.0038 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H83F/H126F, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H83F/H126F | Escherichia coli | L-Threonine | 0.0073 | 21 | 3.3 × 10⁻⁴ | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H83F/H126F, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H83N | Escherichia coli | L-allo-Threonine | 1.28 | 1.7 | 0.75 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H83N, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant H83N | Escherichia coli | L-Threonine | 0.28 | 38 | 0.0067 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant H83N, L-Threonine |
| low-specificity L-threonine aldolase (eTA)variant K222A | Escherichia coli | L-allo-Threonine | 1.3 | 1.2 | 1.12 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant K222A, L-allo-Threonine |
| low-specificity L-threonine aldolase (eTA)variant K222A | Escherichia coli | L-Threonine | 0.72 | 72 | 0.01 | pH 7, 30 °C | PMID 24165453 | Open record: low-specificity L-threonine aldolase (eTA) variant K222A, L-Threonine |