EC 4.1.3.36: 1,4-dihydroxy-2-naphthoyl-CoA synthase
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CatLog read 6 records for EC 4.1.3.36 from 1 paper, for 2 organisms. Names in these papers: mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase), ecMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 7 records for EC 4.1.3.36 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.1.3.36 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Mechanism of the intramolecular Claisen condensation reaction catalyzed by MenB, a crotonase superfamily member | Escherichia coli, Mycobacterium tuberculosis | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| ecMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase) | Escherichia coli | O-succinylbenzoyl-CoA | 0.062 | 0.0259 | 2.4 | pH 7, 25 °C | PMID 21830810 | Open record: ecMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase), O-succinylbenzoyl-CoA |
| mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase) | Mycobacterium tuberculosis | O-succinylbenzoyl-CoA | 0.462 | 0.0224 | 21 | pH 7, 25 °C | PMID 21830810 | Open record: mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase), O-succinylbenzoyl-CoA |
| mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase) | Mycobacterium tuberculosis | OCPB-CoA | 2.5 × 10⁻⁴ | 0.106 | 0.0024 | pH 7, 25 °C | PMID 21830810 | Open record: mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase), OCPB-CoA |
| mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase)variant D185E | Mycobacterium tuberculosis | O-succinylbenzoyl-CoA | 0.0023 | 0.0048 | 0.48 | pH 7, 25 °C | PMID 21830810 | Open record: mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase) variant D185E, O-succinylbenzoyl-CoA |
| mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase)variant D185N | Mycobacterium tuberculosis | O-succinylbenzoyl-CoA | 2.2 × 10⁻⁴ | 0.0031 | 0.07 | pH 7, 25 °C | PMID 21830810 | Open record: mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase) variant D185N, O-succinylbenzoyl-CoA |
| mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase)variant S190A | Mycobacterium tuberculosis | O-succinylbenzoyl-CoA | 0.0017 | 0.0402 | 0.04 | pH 7, 25 °C | PMID 21830810 | Open record: mtMenB (1,4-dihydroxy-2-naphthoyl-CoA synthase) variant S190A, O-succinylbenzoyl-CoA |