EC 4.2.2.21: chondroitin-sulfate-ABC exolyase

LyasesOpen in Browse

CatLog read 38 records for EC 4.2.2.21 from 3 papers, for 2 organisms. Names in these papers: chondroitinase ABC (BactnABC, chondroitin lyase ABC), chondroitin sulfate ABC lyase (BactnABC), chondroitinase ABC II (cABCII).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 13 records for EC 4.2.2.21 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.2.2.21 in Browse.

Papers

Papers with records for EC 4.2.2.21
Paper	Organisms	Records
Composite active site of chondroitin lyase ABC accepting both epimers of uronic acid	Bacteroides thetaiotaomicron	16
Characterization of chondroitin sulfate lyase ABC from Bacteroides thetaiotaomicron WAL2926	Bacteroides thetaiotaomicron	15
Recombinant expression, purification, and biochemical characterization of chondroitinase ABC II from Proteus vulgaris	Proteus vulgaris	7

Records

Records for EC 4.2.2.21 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
chondroitin sulfate ABC lyase (BactnABC)	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	263.2	—	3958	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC), chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	—	—	5352	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC), chondroitin 6-sulfate
chondroitin sulfate ABC lyase (BactnABC)	Bacteroides thetaiotaomicron	dermatan sulfate	—	—	638	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC), dermatan sulfate
chondroitin sulfate ABC lyase (BactnABC)variant E628Q	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	10.38	0.158	67	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant E628Q, chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant E628Q	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	4.42	0.035	127	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant E628Q, chondroitin 6-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H344N	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	42.2	0.039	1.08 × 10³	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H344N, chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H344N	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	18.7	0.084	228	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H344N, chondroitin 6-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H344N	Bacteroides thetaiotaomicron	dermatan sulfate	9.07	0.09	102	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H344N, dermatan sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H344Q	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	16.78	0.073	230	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H344Q, chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H345N	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	21	0.061	343	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H345N, chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H345N	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	6.6	0.026	252	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H345N, chondroitin 6-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H345Q	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	23.47	0.045	522	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H345Q, chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H345Q	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	10.85	0.102	107	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H345Q, chondroitin 6-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H453N	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	13.15	0.034	387	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H453N, chondroitin 4-sulfate
chondroitin sulfate ABC lyase (BactnABC)variant H453N	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	6.88	0.012	563	pH 7.6, 37 °C	PMID 18512954	Open record: chondroitin sulfate ABC lyase (BactnABC) variant H453N, chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	263.2	0.067	3928	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC), chondroitin 4-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	173.4	0.033	5255	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC), chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)	Bacteroides thetaiotaomicron	dermatan sulfate	38.45	0.061	630	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC), dermatan sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H344A	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	92.67	0.202	458	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H344A, chondroitin 4-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H344A	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	35.72	0.134	267	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H344A, chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H345A	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	63.8	0.171	373	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H345A, chondroitin 4-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H345A	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	30.87	0.195	158	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H345A, chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H453A	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	17.62	0.038	463	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H453A, chondroitin 4-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H453A	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	6.42	0.02	322	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H453A, chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant H453A	Bacteroides thetaiotaomicron	dermatan sulfate	5.87	0.044	133	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant H453A, dermatan sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant Q173A	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	123.2	0.102	1207	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant Q173A, chondroitin 4-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant Q173A	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	33.07	0.05	662	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant Q173A, chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant Q173A	Bacteroides thetaiotaomicron	dermatan sulfate	6.8	0.071	95	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant Q173A, dermatan sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant R267A	Bacteroides thetaiotaomicron	chondroitin 4-sulfate	205.3	0.109	1883	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant R267A, chondroitin 4-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant R267A	Bacteroides thetaiotaomicron	chondroitin 6-sulfate	61.77	0.098	630	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant R267A, chondroitin 6-sulfate
chondroitinase ABC (BactnABC, chondroitin lyase ABC)variant R267A	Bacteroides thetaiotaomicron	dermatan sulfate	4.17	0.071	58	pH 7.6, 37 °C	PMID 18227125	Open record: chondroitinase ABC (BactnABC, chondroitin lyase ABC) variant R267A, dermatan sulfate
chondroitinase ABC II (cABCII)	Proteus vulgaris	Chondroitin-4-sulfate	16.7	0.0161	1 × 10³	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII), Chondroitin-4-sulfate
chondroitinase ABC II (cABCII)	Proteus vulgaris	Chondroitin-6-sulfate	21.7	0.0098	2.2 × 10³	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII), Chondroitin-6-sulfate
chondroitinase ABC II (cABCII)	Proteus vulgaris	Dermatan sulfate	19.17	0.0192	1 × 10³	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII), Dermatan sulfate
chondroitinase ABC II (cABCII)variant H452A	Proteus vulgaris	Chondroitin-6-sulfate	0.168	0.007	23	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII) variant H452A, Chondroitin-6-sulfate
chondroitinase ABC II (cABCII)variant H452A	Proteus vulgaris	Dermatan sulfate	0.072	0.0091	8.3	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII) variant H452A, Dermatan sulfate
chondroitinase ABC II (cABCII)variant H456A	Proteus vulgaris	Chondroitin-6-sulfate	7.13	0.0104	680	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII) variant H456A, Chondroitin-6-sulfate
chondroitinase ABC II (cABCII)variant H456A	Proteus vulgaris	Dermatan sulfate	2.4	0.0076	320	pH 8, 37 °C	PMID 18849565	Open record: chondroitinase ABC II (cABCII) variant H456A, Dermatan sulfate