EC 4.2.3.75: (-)-germacrene D synthase
LyasesOpen in Browse
CatLog read 5 records for EC 4.2.3.75 from 1 paper, for 1 organism. Names in these papers: germacradienol-geosmin synthase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 3 records for EC 4.2.3.75 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.2.3.75 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme | Streptomyces coelicolor | 5 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| germacradienol-geosmin synthasevariant D86E | Streptomyces coelicolor | farnesyl diphosphate | 1.3 × 10⁻⁴ | 1.9 × 10⁻⁴ | 0.68 | pH 8.2, 30 °C | PMID 17873868 | Open record: germacradienol-geosmin synthase variant D86E, farnesyl diphosphate |
| germacradienol-geosmin synthasevariant L90D | Streptomyces coelicolor | farnesyl diphosphate | 5.5 × 10⁻⁴ | 0.0058 | 0.095 | pH 8.2, 30 °C | PMID 17873868 | Open record: germacradienol-geosmin synthase variant L90D, farnesyl diphosphate |
| germacradienol-geosmin synthasevariant S233A | Streptomyces coelicolor | farnesyl diphosphate | 8.8 × 10⁻⁵ | 0.0022 | 0.04 | pH 8.2, 30 °C | PMID 17873868 | Open record: germacradienol-geosmin synthase variant S233A, farnesyl diphosphate |
| germacradienol-geosmin synthasevariant S272A | Streptomyces coelicolor | farnesyl diphosphate | 5.8 × 10⁻⁴ | 5 × 10⁻⁵ | 12 | pH 8.2, 30 °C | PMID 17873868 | Open record: germacradienol-geosmin synthase variant S272A, farnesyl diphosphate |
| germacradienol-geosmin synthasevariant T271A | Streptomyces coelicolor | farnesyl diphosphate | 3.3 × 10⁻⁴ | 9.2 × 10⁻⁵ | 3.6 | pH 8.2, 30 °C | PMID 17873868 | Open record: germacradienol-geosmin synthase variant T271A, farnesyl diphosphate |