EC 4.4.1.2: homocysteine desulfhydrase
LyasesOpen in Browse
CatLog read 10 records for EC 4.4.1.2 from 1 paper, for 1 organism. Names in these papers: cystathionine γ-lyase (polymorphic variant S403), cystathionine γ-lyase (polymorphic variant I403).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 17 records for EC 4.4.1.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 4.4.1.2 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Kinetic properties of polymorphic variants and pathogenic mutants in human cystathionine gamma-lyase | Homo sapiens | 10 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| cystathionine γ-lyase (polymorphic variant I403) | Homo sapiens | cystathionine | 1.9 | 0.6 | 3.2 | 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant I403), cystathionine |
| cystathionine γ-lyase (polymorphic variant I403) | Homo sapiens | cysteine | 0.67 | 3.4 | 0.2 | pH 7, 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant I403), cysteine |
| cystathionine γ-lyase (polymorphic variant I403) | Homo sapiens | homocysteine | 3.7 | 7 | 0.53 | pH 7, 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant I403), homocysteine |
| cystathionine γ-lyase (polymorphic variant S403) | Homo sapiens | cystathionine | 1.7 | 0.4 | 4.2 | 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403), cystathionine |
| cystathionine γ-lyase (polymorphic variant S403) | Homo sapiens | cysteine | 0.67 | 3.5 | 0.19 | pH 7, 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403), cysteine |
| cystathionine γ-lyase (polymorphic variant S403) | Homo sapiens | homocysteine | 3.5 | 5.4 | 0.65 | pH 7, 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403), homocysteine |
| cystathionine γ-lyase (polymorphic variant S403)variant Q240E | Homo sapiens | cystathionine | 0.02 | 0.72 | 0.028 | 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403) variant Q240E, cystathionine |
| cystathionine γ-lyase (polymorphic variant S403)variant T67I | Homo sapiens | cystathionine | 0.45 | 0.6 | 0.86 | 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403) variant T67I, cystathionine |
| cystathionine γ-lyase (polymorphic variant S403)variant T67I | Homo sapiens | cysteine | 0.3 | 4.1 | 0.07 | pH 7, 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403) variant T67I, cysteine |
| cystathionine γ-lyase (polymorphic variant S403)variant T67I | Homo sapiens | homocysteine | 0.82 | 8 | 0.1 | pH 7, 37 °C | PMID 18476726 | Open record: cystathionine γ-lyase (polymorphic variant S403) variant T67I, homocysteine |