EC 5.1.1.4: proline racemase
IsomerasesOpen in Browse
CatLog read 29 records for EC 5.1.1.4 from 1 paper, for 3 organisms. Names in these papers: TlProR (proline racemase/hydroxyproline epimerase), FaProR (proline racemase-like protein), CdProR (proline racemase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 23 records for EC 5.1.1.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 5.1.1.4 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Identification and characterization of bifunctional proline racemase/hydroxyproline epimerase from archaea: discrimination of substrates and molecular evolution | Clostridium difficile, Ferroplasma acidiphilum and 1 more | 29 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| CdProR (proline racemase) | Clostridium difficile | D-proline | 2.48 | 0.612 | 4.08 | pH 8, 50 °C | PMID 25786142 | Open record: CdProR (proline racemase), D-proline |
| CdProR (proline racemase) | Clostridium difficile | L-proline | 14.15 | 8.53 | 1.66 | pH 8, 50 °C | PMID 25786142 | Open record: CdProR (proline racemase), L-proline |
| FaProR (proline racemase-like protein) | Ferroplasma acidiphilum | D-proline | 0.1182 | 1.17 | 0.1015 | pH 8, 50 °C | PMID 25786142 | Open record: FaProR (proline racemase-like protein), D-proline |
| FaProR (proline racemase-like protein) | Ferroplasma acidiphilum | L-proline | 0.597 | 31.6 | 0.0188 | pH 8, 50 °C | PMID 25786142 | Open record: FaProR (proline racemase-like protein), L-proline |
| FaProR (proline racemase-like protein) | Ferroplasma acidiphilum | trans-4-hydroxy-L-proline | 0.0395 | 6.12 | 0.00645 | pH 8, 50 °C | PMID 25786142 | Open record: FaProR (proline racemase-like protein), trans-4-hydroxy-L-proline |
| FaProR (proline racemase-like protein)variant F240W | Ferroplasma acidiphilum | D-proline | 0.1202 | 3.12 | 0.0385 | pH 8, 50 °C | PMID 25786142 | Open record: FaProR (proline racemase-like protein) variant F240W, D-proline |
| FaProR (proline racemase-like protein)variant F240W | Ferroplasma acidiphilum | L-proline | 0.417 | 53 | 0.00788 | pH 8, 50 °C | PMID 25786142 | Open record: FaProR (proline racemase-like protein) variant F240W, L-proline |
| FaProR (proline racemase-like protein)variant F240W | Ferroplasma acidiphilum | trans-4-hydroxy-L-proline | 0.01195 | 2.17 | 0.00552 | pH 8, 50 °C | PMID 25786142 | Open record: FaProR (proline racemase-like protein) variant F240W, trans-4-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase) | Thermococcus litoralis | cis-4-hydroxy-D-proline | 3.83 | 6.65 | 0.58 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase), cis-4-hydroxy-D-proline |
| TlProR (proline racemase/hydroxyproline epimerase) | Thermococcus litoralis | D-proline | 2.22 | 0.0919 | 26.2 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase), D-proline |
| TlProR (proline racemase/hydroxyproline epimerase) | Thermococcus litoralis | L-proline | 2.78 | 1.21 | 2.3 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase), L-proline |
| TlProR (proline racemase/hydroxyproline epimerase) | Thermococcus litoralis | trans-3-hydroxy-L-proline | 3.6 | 0.502 | 7.2 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase), trans-3-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase) | Thermococcus litoralis | trans-4-hydroxy-L-proline | 12.13 | 6.08 | 2.03 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase), trans-4-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62S | Thermococcus litoralis | cis-4-hydroxy-D-proline | 0.01432 | 3.14 | 0.00457 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62S, cis-4-hydroxy-D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62S | Thermococcus litoralis | D-proline | 0.0258 | 4 | 0.00645 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62S, D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62S | Thermococcus litoralis | L-proline | 0.2 | 154 | 0.00129 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62S, L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62S | Thermococcus litoralis | trans-4-hydroxy-L-proline | 0.0392 | 6.22 | 0.00632 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62S, trans-4-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62V | Thermococcus litoralis | D-proline | 0.0235 | 0.156 | 0.1507 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62V, D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62V | Thermococcus litoralis | L-proline | 0.0918 | 1.93 | 0.048 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62V, L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant F62V | Thermococcus litoralis | trans-4-hydroxy-L-proline | 0.1307 | 0.905 | 0.1445 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant F62V, trans-4-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant L221H | Thermococcus litoralis | cis-4-hydroxy-D-proline | 0.111 | 4.18 | 0.0265 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant L221H, cis-4-hydroxy-D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant L221H | Thermococcus litoralis | D-proline | 0.288 | 2.54 | 0.114 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant L221H, D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant L221H | Thermococcus litoralis | L-proline | 0.923 | 20.5 | 0.0452 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant L221H, L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant L221H | Thermococcus litoralis | trans-4-hydroxy-L-proline | 0.65 | 6.5 | 0.1002 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant L221H, trans-4-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant W241F | Thermococcus litoralis | cis-4-hydroxy-D-proline | 0.697 | 6.7 | 0.1042 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant W241F, cis-4-hydroxy-D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant W241F | Thermococcus litoralis | D-proline | 3.18 | 0.194 | 16.5 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant W241F, D-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant W241F | Thermococcus litoralis | L-proline | 3.17 | 1.29 | 2.45 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant W241F, L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant W241F | Thermococcus litoralis | trans-3-hydroxy-L-proline | 0.292 | 16.4 | 0.0178 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant W241F, trans-3-hydroxy-L-proline |
| TlProR (proline racemase/hydroxyproline epimerase)variant W241F | Thermococcus litoralis | trans-4-hydroxy-L-proline | 1.533 | 4.28 | 0.362 | pH 8, 50 °C | PMID 25786142 | Open record: TlProR (proline racemase/hydroxyproline epimerase) variant W241F, trans-4-hydroxy-L-proline |