EC 5.1.3.11: cellobiose epimerase

IsomerasesOpen in Browse

CatLog read 68 records for EC 5.1.3.11 from 11 papers, for 6 organisms. Names in these papers: cellobiose 2-epimerase (CsCE), cellobiose 2-epimerase (RaCE), cellobiose 2-epimerase (DtCE), cellobiose 2-epimerase (rBfCE) and 2 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 45 records for EC 5.1.3.11 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 5.1.3.11 in Browse.

Papers

Papers with records for EC 5.1.3.11
Paper	Organisms	Records
Site-directed mutagenesis of possible catalytic residues of cellobiose 2-epimerase from Ruminococcus albus	Ruminococcus albus	17
Insight into the potential factors influencing the catalytic direction in cellobiose 2-epimerase by crystallization and mutagenesis	Caldicellulosiruptor saccharolyticus	11
Semi-rational design and molecular dynamics simulations study of the thermostability enhancement of cellobiose 2-epimerases	Caldicellulosiruptor saccharolyticus	9
Reshaping the Binding Pocket of Cellobiose 2-Epimerase for Improved Substrate Affinity and Isomerization Activity for Enabling Green Synthesis of Lactulose	Caldicellulosiruptor saccharolyticus	8
doi:10.1016/j.molcatb.2016.11.022	Caldicellulosiruptor saccharolyticus, Dictyoglomus turgidum	6
Enhancement of isomerization activity and lactulose production of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus	Caldicellulosiruptor saccharolyticus	5
Rational Engineering of Cellobiose 2-Epimerase Through Flexible Loop Modulation and Structure-Guided Sequence Alignment for Enhanced Lactulose Synthesis	Caldicellulosiruptor saccharolyticus	3
doi:10.1016/j.molcatb.2015.07.007	Caldicellulosiruptor saccharolyticus	3
Identification of the cellobiose 2-epimerase gene in the genome of Bacteroides fragilis NCTC 9343	Bacteroides fragilis	2
Biochemical characterization of a thermophilic cellobiose 2-epimerase from a thermohalophilic bacterium, Rhodothermus marinus JCM9785	Rhodothermus marinus	2
Molecular Characterization of a Mesophilic Cellobiose 2-Epimerase That Maintains a High Catalytic Efficiency at Low Temperatures	Treponema brennaborense	2

Records

Records for EC 5.1.3.11 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	4-O-beta-D-galactopyranosyl-D-fructofuranose	0.88	257	0.0034	pH 7.5, 50 °C	doi:10.1016/j.molcatb.2016.11.022	Open record: cellobiose 2-epimerase (CsCE), 4-O-beta-D-galactopyranosyl-D-fructofuranose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	4-O-beta-D-galactopyranosyl-D-glucopyranose	303	553	0.55	pH 7.5, 50 °C	doi:10.1016/j.molcatb.2016.11.022	Open record: cellobiose 2-epimerase (CsCE), 4-O-beta-D-galactopyranosyl-D-glucopyranose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	4-O-beta-D-galactopyranosyl-D-mannopyranose	101	276	0.37	pH 7.5, 50 °C	doi:10.1016/j.molcatb.2016.11.022	Open record: cellobiose 2-epimerase (CsCE), 4-O-beta-D-galactopyranosyl-D-mannopyranose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	cellobiose	126.1	417.7	0.3	pH 7, 70 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE), cellobiose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	lactose	43.26	613.5	0.0705	pH 7.5, 80 °C	PMID 27080880	Open record: cellobiose 2-epimerase (CsCE), lactose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	lactose	145.1	705.2	0.21	pH 7, 70 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE), lactose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	lactose	1.57	141	0.011	pH 7, 75 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE), lactose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	lactose	165.1	472.2	0.35	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE), lactose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	lactose	225.6	417.5	0.54	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE), lactose
cellobiose 2-epimerase (CsCE)	Caldicellulosiruptor saccharolyticus	lactose	81.55	581.4	0.14	pH 7.5, 80 °C	doi:10.1016/j.molcatb.2015.07.007	Open record: cellobiose 2-epimerase (CsCE), lactose
cellobiose 2-epimerase (CsCE)variant A12S	Caldicellulosiruptor saccharolyticus	lactose	47.5	537.1	0.0884	pH 7.5, 80 °C	PMID 27080880	Open record: cellobiose 2-epimerase (CsCE) variant A12S, lactose
cellobiose 2-epimerase (CsCE)variant A12S/K328I	Caldicellulosiruptor saccharolyticus	lactose	51.77	475.4	0.1089	pH 7.5, 80 °C	PMID 27080880	Open record: cellobiose 2-epimerase (CsCE) variant A12S/K328I, lactose
cellobiose 2-epimerase (CsCE)variant E161D/N365P	Caldicellulosiruptor saccharolyticus	lactose	75.57	417.9	0.181	pH 7.5, 80 °C	doi:10.1016/j.molcatb.2015.07.007	Open record: cellobiose 2-epimerase (CsCE) variant E161D/N365P, lactose
cellobiose 2-epimerase (CsCE)variant E161D/S180P/S351G	Caldicellulosiruptor saccharolyticus	lactose	72.44	932.8	0.078	pH 7.5, 80 °C	doi:10.1016/j.molcatb.2015.07.007	Open record: cellobiose 2-epimerase (CsCE) variant E161D/S180P/S351G, lactose
cellobiose 2-epimerase (CsCE)variant E174A	Caldicellulosiruptor saccharolyticus	lactose	177.1	485	0.37	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant E174A, lactose
cellobiose 2-epimerase (CsCE)variant E174D	Caldicellulosiruptor saccharolyticus	lactose	35.73	181.2	0.2	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant E174D, lactose
cellobiose 2-epimerase (CsCE)variant E174H	Caldicellulosiruptor saccharolyticus	lactose	140.5	439.8	0.32	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant E174H, lactose
cellobiose 2-epimerase (CsCE)variant G176D	Caldicellulosiruptor saccharolyticus	lactose	97.67	382.4	0.26	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant G176D, lactose
cellobiose 2-epimerase (CsCE)variant G176K	Caldicellulosiruptor saccharolyticus	lactose	188.0	711	0.26	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant G176K, lactose
cellobiose 2-epimerase (CsCE)variant I178D	Caldicellulosiruptor saccharolyticus	lactose	179.6	434.4	0.41	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant I178D, lactose
cellobiose 2-epimerase (CsCE)variant N175K	Caldicellulosiruptor saccharolyticus	lactose	235.8	844.6	0.28	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant N175K, lactose
cellobiose 2-epimerase (CsCE)variant N175K/G176D	Caldicellulosiruptor saccharolyticus	lactose	81.65	813.3	0.1	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant N175K/G176D, lactose
cellobiose 2-epimerase (CsCE)variant Q371A	Caldicellulosiruptor saccharolyticus	lactose	218.5	268.9	0.81	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant Q371A, lactose
cellobiose 2-epimerase (CsCE)variant Q371C	Caldicellulosiruptor saccharolyticus	lactose	218.7	428.4	0.52	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant Q371C, lactose
cellobiose 2-epimerase (CsCE)variant Q371E	Caldicellulosiruptor saccharolyticus	lactose	222.7	269.6	0.83	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant Q371E, lactose
cellobiose 2-epimerase (CsCE)variant Q371F	Caldicellulosiruptor saccharolyticus	lactose	239.6	425.7	0.57	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant Q371F, lactose
cellobiose 2-epimerase (CsCE)variant Q371G	Caldicellulosiruptor saccharolyticus	lactose	230.7	411.9	0.56	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant Q371G, lactose
cellobiose 2-epimerase (CsCE)variant R170A/F171A	Caldicellulosiruptor saccharolyticus	lactose	235.8	844.6	0.28	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant R170A/F171A, lactose
cellobiose 2-epimerase (CsCE)variant R17Q	Caldicellulosiruptor saccharolyticus	lactose	0.2493	241	0.00103	pH 7.5, 80 °C	PMID 41750276	Open record: cellobiose 2-epimerase (CsCE) variant R17Q, lactose
cellobiose 2-epimerase (CsCE)variant R17Q/L184S	Caldicellulosiruptor saccharolyticus	lactose	0.225	195.6	0.00115	pH 7.5, 80 °C	PMID 41750276	Open record: cellobiose 2-epimerase (CsCE) variant R17Q/L184S, lactose
cellobiose 2-epimerase (CsCE)variant R17Q/S142T	Caldicellulosiruptor saccharolyticus	lactose	0.1928	241.3	8 × 10⁻⁴	pH 7.5, 80 °C	PMID 41750276	Open record: cellobiose 2-epimerase (CsCE) variant R17Q/S142T, lactose
cellobiose 2-epimerase (CsCE)variant R5M/A12S/F231L/K328I	Caldicellulosiruptor saccharolyticus	lactose	55.83	402.1	0.1389	pH 7.5, 80 °C	PMID 27080880	Open record: cellobiose 2-epimerase (CsCE) variant R5M/A12S/F231L/K328I, lactose
cellobiose 2-epimerase (CsCE)variant R5M/A12S/I52V/F231L/K328I	Caldicellulosiruptor saccharolyticus	lactose	75.27	358.2	0.2101	pH 7.5, 80 °C	PMID 27080880	Open record: cellobiose 2-epimerase (CsCE) variant R5M/A12S/I52V/F231L/K328I, lactose
cellobiose 2-epimerase (CsCE)variant R5M/I52V/A12S/K328I/F231L	Caldicellulosiruptor saccharolyticus	cellobiose	109.2	735.3	0.15	pH 7, 70 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE) variant R5M/I52V/A12S/K328I/F231L, cellobiose
cellobiose 2-epimerase (CsCE)variant R5M/I52V/A12S/K328I/F231L	Caldicellulosiruptor saccharolyticus	lactose	176.6	1434	0.12	pH 7, 70 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE) variant R5M/I52V/A12S/K328I/F231L, lactose
cellobiose 2-epimerase (CsCE)variant R5M/I52V/A12S/K328I/F231L	Caldicellulosiruptor saccharolyticus	lactose	2.94	253.3	0.012	pH 7, 75 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE) variant R5M/I52V/A12S/K328I/F231L, lactose
cellobiose 2-epimerase (CsCE)variant R5M/I52V/A12S/K328I/F231L/E327D	Caldicellulosiruptor saccharolyticus	cellobiose	83.4	594.9	0.14	pH 7, 70 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE) variant R5M/I52V/A12S/K328I/F231L/E327D, cellobiose
cellobiose 2-epimerase (CsCE)variant R5M/I52V/A12S/K328I/F231L/E327D	Caldicellulosiruptor saccharolyticus	lactose	149.2	1479	0.1	pH 7, 70 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE) variant R5M/I52V/A12S/K328I/F231L/E327D, lactose
cellobiose 2-epimerase (CsCE)variant R5M/I52V/A12S/K328I/F231L/E327D	Caldicellulosiruptor saccharolyticus	lactose	3.02	229.6	0.013	pH 7, 75 °C	PMID 31733243	Open record: cellobiose 2-epimerase (CsCE) variant R5M/I52V/A12S/K328I/F231L/E327D, lactose
cellobiose 2-epimerase (CsCE)variant V177D	Caldicellulosiruptor saccharolyticus	lactose	185.2	451.2	0.41	pH 7.5, 75 °C	PMID 33135681	Open record: cellobiose 2-epimerase (CsCE) variant V177D, lactose
cellobiose 2-epimerase (CsCE)variant W355A	Caldicellulosiruptor saccharolyticus	lactose	233.2	313.9	0.74	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant W355A, lactose
cellobiose 2-epimerase (CsCE)variant W355Q	Caldicellulosiruptor saccharolyticus	lactose	226.7	455	0.5	pH 7.5, 75 °C	PMID 36475670	Open record: cellobiose 2-epimerase (CsCE) variant W355Q, lactose
cellobiose 2-epimerase (DtCE)	Dictyoglomus turgidum	4-O-beta-D-galactopyranosyl-D-fructofuranose	0.54	339	0.0016	pH 7.5, 50 °C	doi:10.1016/j.molcatb.2016.11.022	Open record: cellobiose 2-epimerase (DtCE), 4-O-beta-D-galactopyranosyl-D-fructofuranose
cellobiose 2-epimerase (DtCE)	Dictyoglomus turgidum	4-O-beta-D-galactopyranosyl-D-glucopyranose	237	462	0.51	pH 7.5, 50 °C	doi:10.1016/j.molcatb.2016.11.022	Open record: cellobiose 2-epimerase (DtCE), 4-O-beta-D-galactopyranosyl-D-glucopyranose
cellobiose 2-epimerase (DtCE)	Dictyoglomus turgidum	4-O-beta-D-galactopyranosyl-D-mannopyranose	125	381	0.33	pH 7.5, 50 °C	doi:10.1016/j.molcatb.2016.11.022	Open record: cellobiose 2-epimerase (DtCE), 4-O-beta-D-galactopyranosyl-D-mannopyranose
cellobiose 2-epimerase (RaCE)variant F114A	Ruminococcus albus	cellobiose	4.64	55.6	0.08	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant F114A, cellobiose
cellobiose 2-epimerase (RaCE)variant F114A	Ruminococcus albus	lactose	1.79	95.2	0.019	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant F114A, lactose
cellobiose 2-epimerase (RaCE)variant M106T	Ruminococcus albus	cellobiose	29.7	128	0.23	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M106T, cellobiose
cellobiose 2-epimerase (RaCE)variant M179T	Ruminococcus albus	cellobiose	36.9	146	0.25	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M179T, cellobiose
cellobiose 2-epimerase (RaCE)variant M212T	Ruminococcus albus	cellobiose	31.5	20.1	1.57	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M212T, cellobiose
cellobiose 2-epimerase (RaCE)variant M270T	Ruminococcus albus	cellobiose	14.4	18	0.8	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M270T, cellobiose
cellobiose 2-epimerase (RaCE)variant M378T	Ruminococcus albus	cellobiose	5.16	83.7	0.06	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M378T, cellobiose
cellobiose 2-epimerase (RaCE)variant M380T	Ruminococcus albus	cellobiose	40	34.3	1.17	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M380T, cellobiose
cellobiose 2-epimerase (RaCE)variant M62T	Ruminococcus albus	cellobiose	30.3	53.8	0.58	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M62T, cellobiose
cellobiose 2-epimerase (RaCE)variant M95T	Ruminococcus albus	cellobiose	33.4	56.2	0.61	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M95T, cellobiose
cellobiose 2-epimerase (RaCE)variant M96T	Ruminococcus albus	cellobiose	43.8	121	0.37	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant M96T, cellobiose
cellobiose 2-epimerase (RaCE)variant R377A	Ruminococcus albus	cellobiose	26.6	36.8	0.72	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant R377A, cellobiose
cellobiose 2-epimerase (RaCE)variant R377A	Ruminococcus albus	lactose	20.9	73.3	0.285	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant R377A, lactose
cellobiose 2-epimerase (RaCE)variant W303F	Ruminococcus albus	cellobiose	46.4	108	0.43	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant W303F, cellobiose
cellobiose 2-epimerase (RaCE)variant W303F	Ruminococcus albus	lactose	4.04	145	0.028	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant W303F, lactose
cellobiose 2-epimerase (RaCE)variant W55F	Ruminococcus albus	cellobiose	215	127	1.69	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant W55F, cellobiose
cellobiose 2-epimerase (RaCE)variant W55F	Ruminococcus albus	lactose	78.3	72.3	1.08	pH 7.5, 30 °C	PMID 19330485	Open record: cellobiose 2-epimerase (RaCE) variant W55F, lactose
cellobiose 2-epimerase (rBfCE)	Bacteroides fragilis	cellobiose	67.6	3.75	18	pH 7.5, 30 °C	PMID 19202279	Open record: cellobiose 2-epimerase (rBfCE), cellobiose
cellobiose 2-epimerase (rBfCE)	Bacteroides fragilis	lactose	79.5	6.56	12.1	pH 7.5, 30 °C	PMID 19202279	Open record: cellobiose 2-epimerase (rBfCE), lactose
cellobiose 2-epimerase (RmCE)	Rhodothermus marinus	cellobiose	80.8	27.2	2.97	pH 7, 60 °C	PMID 22056431	Open record: cellobiose 2-epimerase (RmCE), cellobiose
cellobiose 2-epimerase (RmCE)	Rhodothermus marinus	lactose	111	28.8	3.85	pH 7, 60 °C	PMID 22056431	Open record: cellobiose 2-epimerase (RmCE), lactose
cellobiose 2-epimerase (Trbr-CE)	Treponema brennaborense	cellobiose	77.7	32.8	2.369	pH 7, 45 °C	PMID 34231359	Open record: cellobiose 2-epimerase (Trbr-CE), cellobiose
cellobiose 2-epimerase (Trbr-CE)	Treponema brennaborense	lactose	135.1	57.8	2.347	pH 7, 45 °C	PMID 34231359	Open record: cellobiose 2-epimerase (Trbr-CE), lactose