CatLogenzyme kinetics catalog

EC 5.3.3.12: L-dopachrome isomerase

IsomerasesOpen in Browse

CatLog read 14 records for EC 5.3.3.12 from 2 papers, for 1 organism. Names in these papers: macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activity, macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase activity.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 13 records for EC 5.3.3.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 5.3.3.12 in Browse.

Papers

PaperOrganismsRecords
Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutantsMus musculus10
Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibitionMus musculus4

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityMus musculus2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid1600.2800pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityMus musculus2-hydroxy-3-phenylprop-2-enoic acid4100.311.3 × 10³pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant N97AMus musculus2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid580.11530pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant N97AMus musculus2-hydroxy-3-phenylprop-2-enoic acid6600.183.7 × 10³pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant P1AMus musculus2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid4.10.5827pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant P1AMus musculus2-hydroxy-3-phenylprop-2-enoic acid1.70.3035.6pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant P1GMus musculus2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid0.80.1435.6pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant P1GMus musculus2-hydroxy-3-phenylprop-2-enoic acid0.60.1075.6pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant Y95FMus musculus2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid1260.1071.2 × 10³pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase (PPT) activityvariant Y95FMus musculus2-hydroxy-3-phenylprop-2-enoic acid1090.112970pH 6.5, 23 °CPMID 10933783Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase activityMus musculus2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid1600.17940pH 6.5, 23 °CPMID 10360941Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase activityMus musculus2-hydroxy-3-phenylprop-2-enoic acid2900.132.2 × 10³pH 6.5, 23 °CPMID 10360941Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase activityMus musculus3-(4-hydroxyphenyl)-2-oxopropanoic acid1202.774323 °CPMID 10360941Open
macrophage migration inhibitory factor (MIF), phenylpyruvate tautomerase activityMus musculus3-phenyl-2-oxopropanoic acid2854.95823 °CPMID 10360941Open