EC 5.4.4.2: isochorismate synthase
IsomerasesOpen in Browse
CatLog read 14 records for EC 5.4.4.2 from 2 papers, for 2 organisms. Names in these papers: EntC (enterobactin-specific isochorismate synthase), PchA (isochorismate synthase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 35 records for EC 5.4.4.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 5.4.4.2 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Crystal structure of Escherichia coli enterobactin-specific isochorismate synthase (EntC) bound to its reaction product isochorismate: implications for the enzyme mechanism and differential activity… | Escherichia coli | 8 |
| Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities | Pseudomonas aeruginosa | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| EntC (enterobactin-specific isochorismate synthase) | Escherichia coli | chorismate | 0.62 | 0.007 | 88 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase), chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant A303T | Escherichia coli | chorismate | 0.067 | 0.103 | 0.67 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant A303T, chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant F327Y | Escherichia coli | chorismate | 0.13 | 0.076 | 1.7 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant F327Y, chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant F327Y/F359Q | Escherichia coli | chorismate | 0.43 | 0.04 | 10.8 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant F327Y/F359Q, chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant F327Y/I346L | Escherichia coli | chorismate | 0.05 | 0.466 | 0.1 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant F327Y/I346L, chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant F359Q | Escherichia coli | chorismate | 0.6 | 0.066 | 8.3 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant F359Q, chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant F359Q/I346L | Escherichia coli | chorismate | 0.18 | 0.261 | 0.67 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant F359Q/I346L, chorismate |
| EntC (enterobactin-specific isochorismate synthase)variant I346L | Escherichia coli | chorismate | 0.55 | 0.076 | 6.7 | pH 7 | PMID 20079748 | Open record: EntC (enterobactin-specific isochorismate synthase) variant I346L, chorismate |
| PchA (isochorismate synthase)variant A375T | Pseudomonas aeruginosa | chorismate | 0.0093 | 0.15 | 0.062 | pH 7.5, 25 °C | PMID 24055536 | Open record: PchA (isochorismate synthase) variant A375T, chorismate |
| PchA (isochorismate synthase)variant A375T | Pseudomonas aeruginosa | isochorismate | 4.4 × 10⁻⁴ | 0.012 | 0.0366 | pH 7.5, 25 °C | PMID 24055536 | Open record: PchA (isochorismate synthase) variant A375T, isochorismate |
| PchA (isochorismate synthase)variant D310E | Pseudomonas aeruginosa | chorismate | 0.022 | 6 × 10⁻⁴ | 41 | pH 7.5, 25 °C | PMID 24055536 | Open record: PchA (isochorismate synthase) variant D310E, chorismate |
| PchA (isochorismate synthase)variant D310E | Pseudomonas aeruginosa | isochorismate | 6.9 × 10⁻⁴ | 0.0137 | 0.0504 | pH 7.5, 25 °C | PMID 24055536 | Open record: PchA (isochorismate synthase) variant D310E, isochorismate |
| PchA (isochorismate synthase)variant D310E/A375T | Pseudomonas aeruginosa | chorismate | 0.004 | 0.119 | 0.034 | pH 7.5, 25 °C | PMID 24055536 | Open record: PchA (isochorismate synthase) variant D310E/A375T, chorismate |
| PchA (isochorismate synthase)variant D310E/A375T | Pseudomonas aeruginosa | isochorismate | 3.8 × 10⁻⁴ | 0.011 | 0.037 | pH 7.5, 25 °C | PMID 24055536 | Open record: PchA (isochorismate synthase) variant D310E/A375T, isochorismate |