CatLogenzyme kinetics catalog

EC 6.2.1.3: long-chain-fatty-acid-CoA ligase

LigasesOpen in Browse

CatLog read 64 records for EC 6.2.1.3 from 3 papers, for 2 organisms. Names in these papers: long-chain acyl-CoA synthetase isoform 1 (ACSL1), long-chain acyl-CoA synthetase isoform 4 (ACSL4), acyl-CoA synthetase-5.0, acyl-CoA synthetase-5.6 and 5 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 132 records for EC 6.2.1.3 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.2.1.3 in Browse.

Papers

PaperOrganismsRecords
Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acidsRattus norvegicus35
Isolation and characterization of the multiple charge isoforms of acyl-CoA synthetase from Escherichia coliEscherichia coli23
Functional role of fatty acyl-coenzyme A synthetase in the transmembrane movement and activation of exogenous long-chain fatty acids. Amino acid residues within the ATP/AMP signature motif of…Escherichia coli6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
acyl-CoA synthetase-4.6Escherichia coliadenosine 5'-triphosphate—0.05—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-4.6Escherichia colicoenzyme A—0.053—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-4.6Escherichia colidecanoic acid—0.0063—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-4.6Escherichia colilauric acid—0.0019—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-4.6Escherichia colioctanoic acid—7.2 × 10⁻⁴—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-4.6Escherichia colipalmitic acid—2.1 × 10⁻⁴—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-4.6Escherichia colistearic acid—1.7 × 10⁻⁴—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia coliadenosine 5'-triphosphate—0.033—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colicoenzyme A—0.035—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colidecanoic acid—0.004—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colilauric acid—0.002—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colimyristic acid—0.0021—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colioctanoic acid—0.0125—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colipalmitic acid—0.0143—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.0Escherichia colistearic acid—0.0091—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia coliadenosine 5'-triphosphate—0.025—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colicoenzyme A—0.034—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colidecanoic acid—0.0083—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colilauric acid—5.1 × 10⁻⁴—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colimyristic acid—0.0012—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colioctanoic acid—0.0059—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colipalmitic acid—0.0029—pH 7.5, 37 °CPMID 3907712Open
acyl-CoA synthetase-5.6Escherichia colistearic acid—2.8 × 10⁻⁴—pH 7.5, 37 °CPMID 3907712Open
fatty acyl-CoA synthetase FadDEscherichia coliadenosine 5'-triphosphate0.0290.130.223pH 7.5, 37 °CPMID 12034706Open
fatty acyl-CoA synthetase FadDvariant G216AEscherichia coliadenosine 5'-triphosphate0.0080.110.073pH 7.5, 37 °CPMID 12034706Open
fatty acyl-CoA synthetase FadDvariant G219AEscherichia coliadenosine 5'-triphosphate0.0170.060.283pH 7.5, 37 °CPMID 12034706Open
fatty acyl-CoA synthetase FadDvariant K222AEscherichia coliadenosine 5'-triphosphate0.0080.440.018pH 7.5, 37 °CPMID 12034706Open
fatty acyl-CoA synthetase FadDvariant T214AEscherichia coliadenosine 5'-triphosphate0.0030.130.023pH 7.5, 37 °CPMID 12034706Open
fatty acyl-CoA synthetase FadDvariant T217AEscherichia coliadenosine 5'-triphosphate0.0080.530.015pH 7.5, 37 °CPMID 12034706Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicusarachidonic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0063—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicusarachidonic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0073—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicuslinoleic acidpurified FLAG-tagged enzyme (1 µg protein)—0.005—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicuslinoleic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.007—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicusoleic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0067—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicusoleic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0147—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicuspalmitic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0027—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicuspalmitic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0021—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicusstearic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0066—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 1 (ACSL1)Rattus norvegicusstearic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0115—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 3 (ACSL3)Rattus norvegicusarachidonic acid—0.0043—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 3 (ACSL3)Rattus norvegicuslinoleic acid—0.0073—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 3 (ACSL3)Rattus norvegicusoleic acid—0.0053—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 3 (ACSL3)Rattus norvegicuspalmitic acid—0.004—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 3 (ACSL3)Rattus norvegicusstearic acid—0.0031—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicusarachidonic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0114—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicusarachidonic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0075—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicuslinoleic acidpurified FLAG-tagged enzyme (1 µg protein)—0.004—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicuslinoleic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0133—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicusoleic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0167—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicusoleic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0036—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicuspalmitic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0045—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicuspalmitic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0248—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicusstearic acidpurified FLAG-tagged enzyme (1 µg protein)—0.0029—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 4 (ACSL4)Rattus norvegicusstearic acidoverexpressed in COS7 cells from pcDNA3.1 (rat cDNA)—0.0125—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 5 (ACSL5)Rattus norvegicusarachidonic acid—0.0018—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 5 (ACSL5)Rattus norvegicuslinoleic acid—0.0058—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 5 (ACSL5)Rattus norvegicusoleic acid—0.0063—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 5 (ACSL5)Rattus norvegicuspalmitic acid—0.0065—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 5 (ACSL5)Rattus norvegicusstearic acid—0.0044—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 6 (ACSL6)Rattus norvegicusarachidonic acid—0.0029—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 6 (ACSL6)Rattus norvegicuslinoleic acid—0.006—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 6 (ACSL6)Rattus norvegicusoleic acid—0.0044—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 6 (ACSL6)Rattus norvegicuspalmitic acid—0.003—pH 8, 37 °CPMID 28209804Open
long-chain acyl-CoA synthetase isoform 6 (ACSL6)Rattus norvegicusstearic acid—0.0044—pH 8, 37 °CPMID 28209804Open