EC 6.2.1.40: 4-hydroxybutyrate-CoA ligase (AMP-forming)
LigasesOpen in Browse
CatLog read 12 records for EC 6.2.1.40 from 1 paper, for 1 organism. Names in these papers: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 1 record for EC 6.2.1.40 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.2.1.40 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea | Metallosphaera sedula | 12 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406) | Metallosphaera sedula | 3-hydroxypropionate | 2.6 | 0.81 | 3.2 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), 3-hydroxypropionate |
| 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406) | Metallosphaera sedula | 4-hydroxybutyrate | 1.8 | 2 | 0.91 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), 4-hydroxybutyrate |
| 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406) | Metallosphaera sedula | Acetate | 6.4 | 2.03 | 3.2 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Acetate |
| 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406) | Metallosphaera sedula | Butyrate | 8.4 | 0.32 | 26 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Butyrate |
| 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406) | Metallosphaera sedula | Propionate | 16.2 | 0.38 | 43 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Propionate |
| 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406) | Metallosphaera sedula | Valerate | 5.6 | 0.74 | 7.5 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (acetyl-CoA synthetase, Msed_0406), Valerate |
| 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394) | Metallosphaera sedula | 3-hydroxypropionate | 0.08 | 1.88 | 0.04 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), 3-hydroxypropionate |
| 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394) | Metallosphaera sedula | 4-hydroxybutyrate | 0.24 | 1.54 | 0.16 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), 4-hydroxybutyrate |
| 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394) | Metallosphaera sedula | Acetate | 0.14 | 0.68 | 0.2 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Acetate |
| 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394) | Metallosphaera sedula | Butyrate | 0.23 | 0.06 | 3.7 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Butyrate |
| 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394) | Metallosphaera sedula | Propionate | 0.21 | 0.54 | 0.39 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Propionate |
| 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394) | Metallosphaera sedula | Valerate | 0.22 | 0.12 | 2 | pH 7.9, 75 °C | PMID 23258541 | Open record: 4-hydroxybutyrate-CoA synthetase (AMP-dependent synthetase and ligase, Msed_0394), Valerate |