CatLogenzyme kinetics catalog

EC 6.3.2.5: phosphopantothenate-cysteine ligase (CTP)

LigasesOpen in Browse

CatLog read 12 records for EC 6.3.2.5 from 3 papers, for 3 organisms. Names in these papers: phosphopantothenoylcysteine synthetase (PPCS), Dfp (CoaBC), bifunctional phosphopantothenoylcysteine synthetase / phosphopantothenoylcysteine decarboxylase.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 1 record for EC 6.3.2.5 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.2.5 in Browse.

Papers

PaperOrganismsRecords
Kinetic characterization of human phosphopantothenoylcysteine synthetaseHomo sapiens6
Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteriaEscherichia coli3
Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalisEnterococcus faecalis3

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
Dfp (CoaBC), bifunctional phosphopantothenoylcysteine synthetase / phosphopantothenoylcysteine decarboxylaseEscherichia coli4'-phosphopantothenate0.880.293.0 calc.pH 7.6PMID 11278255Open
Dfp (CoaBC), bifunctional phosphopantothenoylcysteine synthetase / phosphopantothenoylcysteine decarboxylaseEscherichia colicytidine 5'-triphosphate—0.29—pH 7.6PMID 11278255Open
Dfp (CoaBC), bifunctional phosphopantothenoylcysteine synthetase / phosphopantothenoylcysteine decarboxylaseEscherichia coliL-cysteine—0.24—pH 7.6PMID 11278255Open
phosphopantothenoylcysteine synthetase (PPCS)Enterococcus faecalis(R)-4'-phosphopantothenate2.90.017170 calc.pH 7.6, 37 °CPMID 19182993Open
phosphopantothenoylcysteine synthetase (PPCS)Enterococcus faecaliscytidine 5'-triphosphate—0.156—pH 7.6, 37 °CPMID 19182993Open
phosphopantothenoylcysteine synthetase (PPCS)Enterococcus faecalisL-cysteine—0.086—pH 7.6, 37 °CPMID 19182993Open
phosphopantothenoylcysteine synthetase (PPCS)Homo sapiens(R)-4'-phosphopantothenateATP conditions (A = ATP); cosubstrate ATP, L-cysteine—0.013—pH 7.6, 37 °CPMID 19683078Open
phosphopantothenoylcysteine synthetase (PPCS)Homo sapiens(R)-4'-phosphopantothenateCTP conditions (A = CTP); cosubstrate CTP, L-cysteine—0.057—pH 7.6, 37 °CPMID 19683078Open
phosphopantothenoylcysteine synthetase (PPCS)Homo sapiensadenosine 5'-triphosphate0.56——pH 7.6, 37 °CPMID 19683078Open
phosphopantothenoylcysteine synthetase (PPCS)Homo sapienscytidine 5'-triphosphate0.530.2652.0 calc.pH 7.6, 37 °CPMID 19683078Open
phosphopantothenoylcysteine synthetase (PPCS)Homo sapiensL-cysteineATP conditions (A = ATP); ATP—0.014—pH 7.6, 37 °CPMID 19683078Open
phosphopantothenoylcysteine synthetase (PPCS)Homo sapiensL-cysteineCTP conditions (A = CTP); CTP—0.016—pH 7.6, 37 °CPMID 19683078Open