CatLogenzyme kinetics catalog

EC 6.3.4.5: argininosuccinate synthase

LigasesOpen in Browse

CatLog read 23 records for EC 6.3.4.5 from 2 papers, for 2 organisms. Names in these papers: argininosuccinate synthase, argininosuccinate synthetase (SyArgG).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 38 records for EC 6.3.4.5 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 6.3.4.5 in Browse.

Papers

PaperOrganismsRecords
Detection of kinetically abnormal argininosuccinate synthase in neonatal citrullinemia by conversion of citrulline to arginine in intact fibroblastsHomo sapiens20
Arginine inhibits the arginine biosynthesis rate-limiting enzyme and leads to the accumulation of intracellular aspartate in Synechocystis sp. PCC 6803Synechocystis sp. PCC 68033

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
argininosuccinate synthaseHomo sapiensadenosine 5'-triphosphate—0.098—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthaseHomo sapiensaspartate—0.014—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthaseHomo sapiensL-citrulline—0.23—37 °CPMID 2791302Open
argininosuccinate synthaseHomo sapiensL-citrulline—0.057—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P1 mutant (mutation not identified)Homo sapiensadenosine 5'-triphosphate—0.079—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P1 mutant (mutation not identified)Homo sapiensaspartate—0.14—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P1 mutant (mutation not identified)Homo sapiensL-citrulline—6.1—37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P1 mutant (mutation not identified)Homo sapiensL-citrulline—0.63—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P2 mutant (mutation not identified)Homo sapiensadenosine 5'-triphosphate—0.088—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P2 mutant (mutation not identified)Homo sapiensaspartate—0.018—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P2 mutant (mutation not identified)Homo sapiensL-citrulline—0.24—37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P2 mutant (mutation not identified)Homo sapiensL-citrulline—0.075—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P3 mutant (mutation not identified), cell line GM03056Homo sapiensadenosine 5'-triphosphate—0.1—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P3 mutant (mutation not identified), cell line GM03056Homo sapiensaspartate—0.013—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P3 mutant (mutation not identified), cell line GM03056Homo sapiensL-citrulline—0.27—37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P3 mutant (mutation not identified), cell line GM03056Homo sapiensL-citrulline—0.061—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P4 mutant (mutation not identified)Homo sapiensadenosine 5'-triphosphate—0.097—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P4 mutant (mutation not identified)Homo sapiensaspartate—0.023—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P4 mutant (mutation not identified)Homo sapiensL-citrulline—0.23—37 °CPMID 2791302Open
argininosuccinate synthasecitrullinemia patient P4 mutant (mutation not identified)Homo sapiensL-citrulline—0.068—pH 8.5, 37 °CPMID 2791302Open
argininosuccinate synthetase (SyArgG)Synechocystis sp. PCC 6803adenosine 5'-triphosphate0.70.262.75pH 9, 38 °CPMID 38478146Open
argininosuccinate synthetase (SyArgG)Synechocystis sp. PCC 6803Aspartate0.770.362.16pH 9, 38 °CPMID 38478146Open
argininosuccinate synthetase (SyArgG)Synechocystis sp. PCC 6803Citrulline0.690.351.97pH 9, 38 °CPMID 38478146Open