EC 1.1.1.23: histidinol dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 57 records for EC 1.1.1.23 from 5 papers, for 7 organisms. Names in these papers: L-histidinol dehydrogenase (HDH), L-histidinol dehydrogenase, histidinol dehydrogenase, histidinol dehydrogenase (HDH) and 1 more.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 25 records for EC 1.1.1.23 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.23 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Mutagenesis of histidinol dehydrogenase reveals roles for conserved histidine residues | Salmonella typhimurium | 22 |
| Conserved cysteine residues of histidinol dehydrogenase are not involved in catalysis. Novel chemistry required for enzymatic aldehyde oxidation | Salmonella typhimurium | 12 |
| Purification and properties of histidinol dehydrogenases from psychrophilic, mesophilic and thermophilic bacilli | Bacillus caldolyticus, Bacillus psychrophilus and 2 more | 10 |
| Continuous Directed Evolution of a Short-Lived Plant Histidinol Dehydrogenase | Arabidopsis thaliana | 7 |
| doi:10.1039/c6ra03020c | Mycobacterium tuberculosis | 6 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| histidinol dehydrogenase | Bacillus caldolyticus | L-histidinol | — | 0.048 | — | pH 9.8, 87 °C | PMID 921748 | Open record: histidinol dehydrogenase, L-histidinol |
| histidinol dehydrogenase | Bacillus caldolyticus | NAD+ | — | 0.2 | — | pH 9.8, 87 °C | PMID 921748 | Open record: histidinol dehydrogenase, NAD+ |
| histidinol dehydrogenase | Bacillus psychrophilus | L-histidinol | — | 0.048 | — | pH 9.8, 25 °C | PMID 921748 | Open record: histidinol dehydrogenase, L-histidinol |
| histidinol dehydrogenase | Bacillus psychrophilus | NAD+ | — | 0.2 | — | pH 9.8, 25 °C | PMID 921748 | Open record: histidinol dehydrogenase, NAD+ |
| histidinol dehydrogenase | Bacillus stearothermophilus | L-histidinol | — | 0.048 | — | pH 9.8, 74 °C | PMID 921748 | Open record: histidinol dehydrogenase, L-histidinol |
| histidinol dehydrogenase | Bacillus stearothermophilus | NAD+ | — | 0.2 | — | pH 9.8, 74 °C | PMID 921748 | Open record: histidinol dehydrogenase, NAD+ |
| histidinol dehydrogenase | Bacillus subtilis | L-histidinol | — | 0.048 | — | pH 9.8, 41 °C | PMID 921748 | Open record: histidinol dehydrogenase, L-histidinol |
| histidinol dehydrogenase | Bacillus subtilis | L-histidinol | — | 0.048 | — | pH 9.8, 92 °C | PMID 921748 | Open record: histidinol dehydrogenase, L-histidinol |
| histidinol dehydrogenase | Bacillus subtilis | NAD+ | — | 0.2 | — | pH 9.8, 41 °C | PMID 921748 | Open record: histidinol dehydrogenase, NAD+ |
| histidinol dehydrogenase | Bacillus subtilis | NAD+ | — | 0.2 | — | pH 9.8, 92 °C | PMID 921748 | Open record: histidinol dehydrogenase, NAD+ |
| histidinol dehydrogenase (HDH) | Arabidopsis thaliana | histidinol | 2.7 | 0.0209 | 131 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH), histidinol |
| histidinol dehydrogenase (HDH)variant A0_3.1 | Arabidopsis thaliana | histidinol | 1.1 | 0.0048 | 229 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH) variant A0_3.1, histidinol |
| histidinol dehydrogenase (HDH)variant A0_4 | Arabidopsis thaliana | histidinol | 2.6 | 0.0178 | 153 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH) variant A0_4, histidinol |
| histidinol dehydrogenase (HDH)variant A72_1.1 | Arabidopsis thaliana | histidinol | 1.6 | 0.0137 | 118 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH) variant A72_1.1, histidinol |
| histidinol dehydrogenase (HDH)variant A72_4 | Arabidopsis thaliana | histidinol | 1 | 0.0059 | 172 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH) variant A72_4, histidinol |
| histidinol dehydrogenase (HDH)variant A72_6 | Arabidopsis thaliana | histidinol | 2.7 | 0.1045 | 26 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH) variant A72_6, histidinol |
| histidinol dehydrogenase (HDH)variant A72_7 | Arabidopsis thaliana | histidinol | 2.3 | 0.0174 | 135 | pH 8.5 | PMID 41688052 | Open record: histidinol dehydrogenase (HDH) variant A72_7, histidinol |
| histidinol dehydrogenase (MtHisD) | Mycobacterium tuberculosis | L-histidinolno Ficoll | 1.436 | 0.02 | 70 | pH 7.2, 25 °C | doi:10.1039/c6ra03020c | Open record: histidinol dehydrogenase (MtHisD), L-histidinol |
| histidinol dehydrogenase (MtHisD) | Mycobacterium tuberculosis | L-histidinol100 g/L Ficoll PM70 | 1.209 | 0.017 | 73 | pH 7.2, 25 °C | doi:10.1039/c6ra03020c | Open record: histidinol dehydrogenase (MtHisD), L-histidinol |
| histidinol dehydrogenase (MtHisD) | Mycobacterium tuberculosis | L-histidinol200 g/L Ficoll PM70 | 1.209 | 0.022 | 60 | pH 7.2, 25 °C | doi:10.1039/c6ra03020c | Open record: histidinol dehydrogenase (MtHisD), L-histidinol |
| histidinol dehydrogenase (MtHisD) | Mycobacterium tuberculosis | NAD+no Ficoll | 1.361 | 2.9 | 0.47 | pH 7.2, 25 °C | doi:10.1039/c6ra03020c | Open record: histidinol dehydrogenase (MtHisD), NAD+ |
| histidinol dehydrogenase (MtHisD) | Mycobacterium tuberculosis | NAD+100 g/L Ficoll PM70 | 1.134 | 2.7 | 0.42 | pH 7.2, 25 °C | doi:10.1039/c6ra03020c | Open record: histidinol dehydrogenase (MtHisD), NAD+ |
| histidinol dehydrogenase (MtHisD) | Mycobacterium tuberculosis | NAD+200 g/L Ficoll PM70 | 0.227 | 3.3 | 0.069 | pH 7.2, 25 °C | doi:10.1039/c6ra03020c | Open record: histidinol dehydrogenase (MtHisD), NAD+ |
| L-histidinol dehydrogenase | Salmonella typhimurium | L-histidinol | 16.7 | 0.011 | 1.5 × 10³ calc. | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase, L-histidinol |
| L-histidinol dehydrogenase | Salmonella typhimurium | nicotinamide adenine dinucleotide (NAD+) | — | 0.6 | — | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase, nicotinamide adenine dinucleotide (NAD+) |
| L-histidinol dehydrogenasevariant C116A | Salmonella typhimurium | L-histidinol | 12.1 | 0.0194 | 624 calc. | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C116A, L-histidinol |
| L-histidinol dehydrogenasevariant C116A | Salmonella typhimurium | nicotinamide adenine dinucleotide (NAD+) | — | 0.9 | — | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C116A, nicotinamide adenine dinucleotide (NAD+) |
| L-histidinol dehydrogenasevariant C116A/C153A | Salmonella typhimurium | L-histidinol | 10.1 | 0.0062 | 1.6 × 10³ calc. | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C116A/C153A, L-histidinol |
| L-histidinol dehydrogenasevariant C116A/C153A | Salmonella typhimurium | nicotinamide adenine dinucleotide (NAD+) | — | 0.5 | — | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C116A/C153A, nicotinamide adenine dinucleotide (NAD+) |
| L-histidinol dehydrogenasevariant C116S | Salmonella typhimurium | L-histidinol | 11.8 | 0.039 | 300 calc. | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C116S, L-histidinol |
| L-histidinol dehydrogenasevariant C116S | Salmonella typhimurium | nicotinamide adenine dinucleotide (NAD+) | — | 0.4 | — | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C116S, nicotinamide adenine dinucleotide (NAD+) |
| L-histidinol dehydrogenasevariant C153A | Salmonella typhimurium | L-histidinol | 16 | 0.0057 | 2.8 × 10³ calc. | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C153A, L-histidinol |
| L-histidinol dehydrogenasevariant C153A | Salmonella typhimurium | nicotinamide adenine dinucleotide (NAD+) | — | 0.4 | — | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C153A, nicotinamide adenine dinucleotide (NAD+) |
| L-histidinol dehydrogenasevariant C153S | Salmonella typhimurium | L-histidinol | 16.7 | 0.0152 | 1.10 × 10³ calc. | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C153S, L-histidinol |
| L-histidinol dehydrogenasevariant C153S | Salmonella typhimurium | nicotinamide adenine dinucleotide (NAD+) | — | 1.9 | — | pH 9.2, 30 °C | PMID 8314784 | Open record: L-histidinol dehydrogenase variant C153S, nicotinamide adenine dinucleotide (NAD+) |
| L-histidinol dehydrogenase (HDH) | Salmonella typhimurium | imidazolyl propanediol | 0.08 | 0.24 | 0.33 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH), imidazolyl propanediol |
| L-histidinol dehydrogenase (HDH) | Salmonella typhimurium | L-histidinol | 13 | 0.015 | 870 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH), L-histidinol |
| L-histidinol dehydrogenase (HDH) | Salmonella typhimurium | NAD+NADH production at 340 nm (standard assay, Loper method) | — | 1.1 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH), NAD+ |
| L-histidinol dehydrogenase (HDH) | Salmonella typhimurium | NAD+NAD 0.2-10 mM with 2 mM imidazolyl propanediol | — | 7.3 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH), NAD+ |
| L-histidinol dehydrogenase (HDH)variant H261N | Salmonella typhimurium | L-histidinol | 0.0019 | 0.0311 | 0.061 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H261N, L-histidinol |
| L-histidinol dehydrogenase (HDH)variant H261N | Salmonella typhimurium | NAD+ | — | 2.1 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H261N, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H326N | Salmonella typhimurium | imidazolyl propanediol | 0.003 | 0.026 | 0.12 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H326N, imidazolyl propanediol |
| L-histidinol dehydrogenase (HDH)variant H326N | Salmonella typhimurium | L-histidinolNADH production at 340 nm (standard assay, Loper method) | 0.025 | 0.0017 | 15 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H326N, L-histidinol |
| L-histidinol dehydrogenase (HDH)variant H326N | Salmonella typhimurium | L-histidinol | 0.012 | — | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H326N, L-histidinol |
| L-histidinol dehydrogenase (HDH)variant H326N | Salmonella typhimurium | NAD+NADH production at 340 nm (standard assay, Loper method) | — | 0.9 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H326N, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H326N | Salmonella typhimurium | NAD+NAD 0.2-10 mM with 2 mM imidazolyl propanediol | — | 0.7 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H326N, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H366N | Salmonella typhimurium | imidazolyl propanediol | 0.0027 | 0.9 | 0.0030 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H366N, imidazolyl propanediol |
| L-histidinol dehydrogenase (HDH)variant H366N | Salmonella typhimurium | L-histidinol | 4.9 | 0.1119 | 44 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H366N, L-histidinol |
| L-histidinol dehydrogenase (HDH)variant H366N | Salmonella typhimurium | NAD+NADH production at 340 nm (standard assay, Loper method) | — | 1.3 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H366N, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H366N | Salmonella typhimurium | NAD+NAD 0.2-10 mM with 10 mM imidazolyl propanediol | — | 0.9 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H366N, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H418Q | Salmonella typhimurium | imidazolyl propanediol | 0.001 | 0.45 | 0.0022 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H418Q, imidazolyl propanediol |
| L-histidinol dehydrogenase (HDH)variant H418Q | Salmonella typhimurium | L-histidinol | 0.58 | 0.0165 | 35 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H418Q, L-histidinol |
| L-histidinol dehydrogenase (HDH)variant H418Q | Salmonella typhimurium | NAD+NADH production at 340 nm (standard assay, Loper method) | — | 15.3 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H418Q, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H418Q | Salmonella typhimurium | NAD+NAD 0.2-10 mM with 5.8 mM imidazolyl propanediol | — | 14 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H418Q, NAD+ |
| L-histidinol dehydrogenase (HDH)variant H98N | Salmonella typhimurium | imidazolyl propanediol | 0.04 | — | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H98N, imidazolyl propanediol |
| L-histidinol dehydrogenase (HDH)variant H98N | Salmonella typhimurium | L-histidinol | 3.3 | 0.0156 | 210 calc. | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H98N, L-histidinol |
| L-histidinol dehydrogenase (HDH)variant H98N | Salmonella typhimurium | NAD+ | — | 0.6 | — | pH 9, 30 °C | PMID 10353848 | Open record: L-histidinol dehydrogenase (HDH) variant H98N, NAD+ |