CatLogenzyme kinetics catalog

EC 1.1.1.236: tropinone reductase II

OxidoreductasesOpen in Browse

CatLog read 41 records for EC 1.1.1.236 from 4 papers, for 3 organisms. Names in these papers: tropinone reductase II (TR-II), tropinone reductase II (TR-II, pseudotropine-forming), tropinone reductase CoTR, tropinone reductase II (TR II, pseudotropine-forming).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 11 records for EC 1.1.1.236 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.236 in Browse.

Papers

PaperOrganismsRecords
Site-directed mutagenesis of putative substrate-binding residues reveals a mechanism controlling the different stereospecificities of two tropinone reductasesDatura stramonium19
Two Tropinone Reductases with Distinct Stereospecificities from Cultured Roots of Hyoscyamus nigerHyoscyamus niger11
The functional divergence of short-chain dehydrogenases involved in tropinone reductionCochlearia officinalis9
doi:10.1016/0031-9422(92)80247-cDatura stramonium2

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
tropinone reductase CoTRCochlearia officinalis1-methyl-4-piperidinone—7.5832.374pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalis1-propyl-4-piperidinone—1.3420.51pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalis3-methylcyclohexanone—0.0135.171pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalis4-methylcyclohexanone—0.01595.94pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalis8-thiabicyclo[3.2.1]octan-3-one—0.0421.096pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalisnortropinone—2.0020.0089pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalisQuinuclidinone—2.6360.0318pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalistropinoneTable 1—3.290.0073pH 6.4, 30 °CPMID 18221363Open
tropinone reductase CoTRCochlearia officinalistropinonein the text0.023——pH 6.4, 30 °CPMID 18221363Open
tropinone reductase II (TR II, pseudotropine-forming)Datura stramoniumNADPH—0.017—pH 6.25, 30 °Cdoi:10.1016/0031-9422(92)80247-cOpen
tropinone reductase II (TR II, pseudotropine-forming)Datura stramoniumtropinone—0.22—pH 6.25, 30 °Cdoi:10.1016/0031-9422(92)80247-cOpen
tropinone reductase II (TR-II)Datura stramoniumNADPH—0.0187—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)Datura stramoniumtropinone2.730.047657.4 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant E156VDatura stramoniumNADPH—0.0201—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant E156VDatura stramoniumtropinone1.1128.70.0387 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant E156V/Y100HDatura stramoniumNADPH—0.0255—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant E156V/Y100HDatura stramoniumtropinone1.0252.50.0194 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant L210I/L213FDatura stramoniumNADPH—0.00417—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant L210I/L213FDatura stramoniumtropinone1.880.044842.0 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant S148ADatura stramoniumNADPH—0.00172—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant S148ADatura stramoniumtropinone1.770.315.7 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant S148A/E156VDatura stramoniumNADPH—0.00817—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant S148A/E156VDatura stramoniumtropinone2.526.560.384 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100HDatura stramoniumNADPH—0.0112—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100HDatura stramoniumtropinone6.844.561.50 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100H/S148ADatura stramoniumNADPH—0.00405—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100H/S148ADatura stramoniumtropinone4.5819.60.234 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100H/S148A/E156VDatura stramoniumNADPH—0.0124—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100H/S148A/E156VDatura stramoniumtropinone4.8638.10.128 calc.pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II)variant Y100H/S148A/E156V/L210I/L213FDatura stramoniumNADPH—0.0377—pH 7, 28 °CPMID 10347221Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus niger3-Methylcyclohexanone—7.58—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus niger4-Ethylcyclohexanone—0.534—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus niger4-Methylcyclohexanone—2.03—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus niger4-Piperidone—21.6—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigerN-Methyl-4-piperidone—0.77—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigerN-Propyl-4-piperidone—0.265—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigerNADH—7.6—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigerNADP+—0.251—PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigerNADPH—0.0061—pH 5.9PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigerpseudotropine—0.687—PMID 16653065Open
tropinone reductase II (TR-II, pseudotropine-forming)Hyoscyamus nigertropinone—0.034—pH 5.9PMID 16653065Open