CatLogenzyme kinetics catalog

EC 1.1.1.268: 2-(R)-hydroxypropyl-CoM dehydrogenase

OxidoreductasesOpen in Browse

CatLog read 32 records for EC 1.1.1.268 from 2 papers, for 1 organism. Names in these papers: 2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH), R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 4 records for EC 1.1.1.268 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.268 in Browse.

Papers

PaperOrganismsRecords
The stereoselectivity and catalytic properties of Xanthobacter autotrophicus 2-[(R)-2-Hydroxypropylthio]ethanesulfonate dehydrogenase are controlled by interactions between C-terminal arginine…Xanthobacter autotrophicus26
Molecular basis for enantioselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases, a unique pair of stereoselective short-chain dehydrogenases/reductases involved in…Xanthobacter autotrophicus6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(R)-2-butanol0.983280.003pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(R)-2-heptanol1.82.640.68pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(R)-2-hexanol2.74.60.58pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(R)-2-octanol1.71.081.5pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(R)-2-pentanol1.1200.056pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(S)-2-butanol2.23150.0071pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus(S)-2-pentanol2.91530.019pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-(2-ketopropylthio)ethanesulfonate24.50.092270pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-[(R)-2-hydroxypropylthio]ethanesulfonate26.80.102260pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-[(S)-2-hydroxypropylthio]ethanesulfonate0.0440.10.44pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanoneketone reduction (reverse direction); NADH fixed at 0.16 mM0.027525.2 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanone2-butanone reduction; NADH fixed at 160 µM; Table 40.02751.95.2 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanone2-butanone reduction; NADH fixed at 160 µM; Table 40.02852.75.3 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanone2-butanone reduction; NADH fixed at 160 µM; Table 40.09717.20.0056pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanone2-butanone reduction; NADH fixed at 160 µM; Table 40.1119.80.0056pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanone2-butanone reduction; NADH fixed at 160 µM; Table 40.0444.59 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-butanone2-butanone reduction; NADH fixed at 160 µM; Table 40.022882.5 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)Xanthobacter autotrophicus2-propanol2.917260.0017pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R152AXanthobacter autotrophicus2-(2-ketopropylthio)ethanesulfonate1.4270.052pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R152AXanthobacter autotrophicus2-butanone0.028416.8 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R196AXanthobacter autotrophicus2-(2-ketopropylthio)ethanesulfonate2.48.70.27pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R196AXanthobacter autotrophicus2-butanone0.033230.0014pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R203AXanthobacter autotrophicus2-(2-ketopropylthio)ethanesulfonate27.90.4463pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R203AXanthobacter autotrophicus2-butanone0.012393.1 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R209AXanthobacter autotrophicus2-(2-ketopropylthio)ethanesulfonate150.15100pH 7.5, 30 °CPMID 15157110Open
2-[(R)-2-hydroxypropylthio]ethanesulfonate dehydrogenase (R-HPCDH)variant R209AXanthobacter autotrophicus2-butanone0.032843.8 × 10⁻⁴pH 7.5, 30 °CPMID 15157110Open
R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1)Xanthobacter autotrophicus(R)-2-(2-hydroxypropylthio)ethanesulfonate480.096500pH 7.5, 30 °CPMID 20302306Open
R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1)Xanthobacter autotrophicus(R)-2-butanol1.92200.00869pH 7.5, 30 °CPMID 20302306Open
R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1)Xanthobacter autotrophicus(S)-2-(2-hydroxypropylthio)ethanesulfonate0.120.220.53pH 7.5, 30 °CPMID 20302306Open
R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1)Xanthobacter autotrophicus(S)-2-butanol9.33500.0264pH 7.5, 30 °CPMID 20302306Open
R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1)Xanthobacter autotrophicus2-(2-hydroxyethylthio)ethanesulfonate—0.96—pH 7.5, 30 °CPMID 20302306Open
R-HPCDH1 ((R)-2-hydroxypropyl-CoM dehydrogenase 1, XecD1)Xanthobacter autotrophicus2-(2-oxopropylthio)ethanesulfonate290.068420pH 7.5, 30 °CPMID 20302306Open