CatLogenzyme kinetics catalog

EC 1.1.1.337: L-2-hydroxycarboxylate dehydrogenase (NAD+)

OxidoreductasesOpen in Browse

CatLog read 13 records for EC 1.1.1.337 from 1 paper, for 1 organism. Names in these papers: MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 25 records for EC 1.1.1.337 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.337 in Browse.

Papers

PaperOrganismsRecords
Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaeaMethanococcus jannaschii13

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii(R)-Malate—0.31—pH 9.5, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii(S)-2-hydroxyglutaric acid—0.52—pH 9.5, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii(S)-Malate1 mM NAD+ (Table 2 footnote); cosubstrate NAD+—0.02—pH 9.5, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii(S)-Malate1 mM NADP+ (Table 2 footnote); cosubstrate NADP+—0.03—pH 9.5, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii(S)-Sulfolactate1 mM NAD+ (Table 2 footnote); cosubstrate NAD+—0.04—pH 9.5, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii(S)-Sulfolactate1 mM NADP+ (Table 2 footnote); cosubstrate NADP+—0.39—pH 9.5, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschii1-oxo-1,3,4,6-hexanetetracarboxylic acid (racemic; 1 part erythro-KHTCA : 2 parts threo-KHTCA)—15—pH 8, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschiiNADH—0.01—pH 8, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschiiOxalacetate0.3 mM NADH; NADH oxidation followed at 366 nm—0.13—pH 8, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschiiOxalacetate0.3 mM NADPH; NADPH oxidation followed at 366 nm—5.32—pH 8, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschiiSulfopyruvate0.3 mM NADH; NADH oxidation followed at 366 nm—0.04—pH 8, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschiiSulfopyruvate0.3 mM NADPH; NADPH oxidation followed at 366 nm—0.21—pH 8, 70 °CPMID 10850983Open
MdhI (MJ1425-encoded 2-hydroxy acid dehydrogenase)Methanococcus jannaschiiα-Ketoglutarate—1.9—pH 8, 70 °CPMID 10850983Open