CatLogenzyme kinetics catalog

EC 1.1.1.375: L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

OxidoreductasesOpen in Browse

CatLog read 7 records for EC 1.1.1.375 from 1 paper, for 1 organism. Names in these papers: MdhII (MJ0490-encoded malate dehydrogenase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 4 records for EC 1.1.1.375 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.375 in Browse.

Papers

PaperOrganismsRecords
Identification of an archaeal 2-hydroxy acid dehydrogenase catalyzing reactions involved in coenzyme biosynthesis in methanoarchaeaMethanococcus jannaschii7

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschii(S)-Malate1 mM NAD+ (Table 2 footnote); cosubstrate NAD+—0.15—pH 9.5, 70 °CPMID 10850983Open
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschii(S)-Malate1 mM NADP+ (Table 2 footnote); cosubstrate NADP+—0.025—pH 9.5, 70 °CPMID 10850983Open
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschii(S)-Sulfolactate—4.6—pH 9.5, 70 °CPMID 10850983Open
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschiiOxalacetate0.3 mM NADH; NADH oxidation followed at 366 nm—0.25—pH 8, 70 °CPMID 10850983Open
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschiiOxalacetate0.3 mM NADPH; NADPH oxidation followed at 366 nm—0.3—pH 8, 70 °CPMID 10850983Open
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschiiSulfopyruvate0.3 mM NADH; NADH oxidation followed at 366 nm—1.3—pH 8, 70 °CPMID 10850983Open
MdhII (MJ0490-encoded malate dehydrogenase)Methanococcus jannaschiiSulfopyruvate0.3 mM NADPH; NADPH oxidation followed at 366 nm—0.19—pH 8, 70 °CPMID 10850983Open