EC 1.1.1.61: 4-hydroxybutyrate dehydrogenase
OxidoreductasesOpen in Browse
CatLog read 14 records for EC 1.1.1.61 from 3 papers, for 3 organisms. Names in these papers: sulfolactaldehyde (SLA) reductase YihU, 4-hydroxybutanoate dehydrogenase, 4-hydroxybutyrate dehydrogenase.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 16 records for EC 1.1.1.61 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.1.1.61 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| doi:10.1021/acscatal.9b04427 | Escherichia coli | 8 |
| Purification and characterization of the oxygen-sensitive 4-hydroxybutanoate dehydrogenase from Clostridium kluyveri | Clostridium kluyveri | 5 |
| Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid | Porphyromonas gingivalis | 1 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| 4-hydroxybutanoate dehydrogenase | Clostridium kluyveri | 4-hydroxybutanoate | — | 55 | — | pH 9.4, 30 °C | PMID 7606170 | Open record: 4-hydroxybutanoate dehydrogenase, 4-hydroxybutanoate |
| 4-hydroxybutanoate dehydrogenase | Clostridium kluyveri | NAD | — | 0.67 | — | pH 9.4, 30 °C | PMID 7606170 | Open record: 4-hydroxybutanoate dehydrogenase, NAD |
| 4-hydroxybutanoate dehydrogenase | Clostridium kluyveri | NADH | — | 0.15 | — | pH 6.3, 30 °C | PMID 7606170 | Open record: 4-hydroxybutanoate dehydrogenase, NADH |
| 4-hydroxybutanoate dehydrogenase | Clostridium kluyveri | NADPH | — | 0.32 | — | pH 6.3, 30 °C | PMID 7606170 | Open record: 4-hydroxybutanoate dehydrogenase, NADPH |
| 4-hydroxybutanoate dehydrogenase | Clostridium kluyveri | succinic semialdehyde | — | 0.56 | — | pH 6.3, 30 °C | PMID 7606170 | Open record: 4-hydroxybutanoate dehydrogenase, succinic semialdehyde |
| 4-hydroxybutyrate dehydrogenase | Porphyromonas gingivalis | (L)-malate-beta-semialdehyde | — | 5.1 | 0.98 | pH 7.5, 37 °C | PMID 28631755 | Open record: 4-hydroxybutyrate dehydrogenase, (L)-malate-beta-semialdehyde |
| sulfolactaldehyde (SLA) reductase YihU | Escherichia coli | D-sulfolactaldehyde | 332 | 0.3 | 1.09 × 10³ | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU, D-sulfolactaldehyde | |
| sulfolactaldehyde (SLA) reductase YihU | Escherichia coli | NADH | 548 | 0.082 | 6.72 × 10³ | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU, NADH | |
| sulfolactaldehyde (SLA) reductase YihUvariant G122S | Escherichia coli | D-sulfolactaldehyde | 71 | 1.63 | 43 | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU variant G122S, D-sulfolactaldehyde | |
| sulfolactaldehyde (SLA) reductase YihUvariant G122S | Escherichia coli | NADH | 178 | 0.123 | 1.45 × 10³ | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU variant G122S, NADH | |
| sulfolactaldehyde (SLA) reductase YihUvariant R123G | Escherichia coli | D-sulfolactaldehyde | 68 | 7.99 | 8.5 | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU variant R123G, D-sulfolactaldehyde | |
| sulfolactaldehyde (SLA) reductase YihUvariant R123G | Escherichia coli | NADH | 22.1 | 0.009 | 2.36 × 10³ | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU variant R123G, NADH | |
| sulfolactaldehyde (SLA) reductase YihUvariant T124G | Escherichia coli | D-sulfolactaldehyde | 27 | 5.74 | 4.7 | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU variant T124G, D-sulfolactaldehyde | |
| sulfolactaldehyde (SLA) reductase YihUvariant T124G | Escherichia coli | NADH | 12.7 | 0.023 | 570 | doi:10.1021/acscatal.9b04427 | Open record: sulfolactaldehyde (SLA) reductase YihU variant T124G, NADH |