EC 1.13.11.80: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
OxidoreductasesOpen in Browse
CatLog read 15 records for EC 1.13.11.80 from 2 papers, for 1 organism. Names in these papers: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase), DpgC.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 7 records for EC 1.13.11.80 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.13.11.80 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC | Streptomyces toyocaensis | 8 |
| Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis | Streptomyces toyocaensis | 7 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| DpgC | Streptomyces toyocaensis | 3,5-dihydroxyphenylacetyl-CoA | 0.172 | 0.0039 | 44 calc. | PMID 17507985 | Open record: DpgC, 3,5-dihydroxyphenylacetyl-CoA | |
| DpgC | Streptomyces toyocaensis | dioxygen | — | 1.7 | — | PMID 17507985 | Open record: DpgC, dioxygen | |
| DpgCvariant L237T | Streptomyces toyocaensis | 3,5-dihydroxyphenylacetyl-CoA | 0.05 | 0.058 | 0.86 calc. | PMID 17507985 | Open record: DpgC variant L237T, 3,5-dihydroxyphenylacetyl-CoA | |
| DpgCvariant L237T | Streptomyces toyocaensis | dioxygen | — | 2.1 | — | PMID 17507985 | Open record: DpgC variant L237T, dioxygen | |
| DpgCvariant V425T | Streptomyces toyocaensis | 3,5-dihydroxyphenylacetyl-CoA | 0.037 | 0.0138 | 2.7 calc. | PMID 17507985 | Open record: DpgC variant V425T, 3,5-dihydroxyphenylacetyl-CoA | |
| DpgCvariant V425T | Streptomyces toyocaensis | dioxygen | — | 2.6 | — | PMID 17507985 | Open record: DpgC variant V425T, dioxygen | |
| DpgCvariant V429T | Streptomyces toyocaensis | 3,5-dihydroxyphenylacetyl-CoA | 0.019 | 0.0147 | 1.3 calc. | PMID 17507985 | Open record: DpgC variant V429T, 3,5-dihydroxyphenylacetyl-CoA | |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) | Streptomyces toyocaensis | (3,5-dihydroxyphenylacetyl)coenzyme A | 0.172 | 0.0039 | 44 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase), (3,5-dihydroxyphenylacetyl)coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) | Streptomyces toyocaensis | (3-hydroxyphenylacetyl)coenzyme A | 0.1253 | 0.0044 | 28 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase), (3-hydroxyphenylacetyl)coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) | Streptomyces toyocaensis | (4-hydroxyphenylacetyl)coenzyme A | 0.222 | 0.851 | 0.261 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase), (4-hydroxyphenylacetyl)coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) | Streptomyces toyocaensis | phenylacetyl-coenzyme A | 0.064 | 0.102 | 0.63 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase), phenylacetyl-coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase)variant E189Q | Streptomyces toyocaensis | (3,5-dihydroxyphenylacetyl)coenzyme A | 0.0853 | 0.064 | 1.3 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) variant E189Q, (3,5-dihydroxyphenylacetyl)coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase)variant E255Q | Streptomyces toyocaensis | (3,5-dihydroxyphenylacetyl)coenzyme A | 0.153 | 0.0036 | 42 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) variant E255Q, (3,5-dihydroxyphenylacetyl)coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase)variant Q299N | Streptomyces toyocaensis | (3,5-dihydroxyphenylacetyl)coenzyme A | 0.069 | 0.0025 | 28 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) variant Q299N, (3,5-dihydroxyphenylacetyl)coenzyme A |
| DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase)variant R254K | Streptomyces toyocaensis | (3,5-dihydroxyphenylacetyl)coenzyme A | 0.0862 | 0.217 | 0.397 calc. | pH 7.5, 24 °C | PMID 18004875 | Open record: DpgC (3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase) variant R254K, (3,5-dihydroxyphenylacetyl)coenzyme A |