CatLogenzyme kinetics catalog

EC 1.14.11.26: deacetoxycephalosporin-C hydroxylase

OxidoreductasesOpen in Browse

CatLog read 6 records for EC 1.14.11.26 from 1 paper, for 1 organism. Names in these papers: deacetylcephalosporin C synthase (DACS).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 3 records for EC 1.14.11.26 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.11.26 in Browse.

Papers

PaperOrganismsRecords
Modified Deacetylcephalosporin C Synthase for the Biotransformation of Semisynthetic CephalosporinsStreptomyces clavuligerus6

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
deacetylcephalosporin C synthase (DACS)Streptomyces clavuligeruscephalosporin G0.0552.580.0214pH 7.8, 25 °CPMID 27084018Open
deacetylcephalosporin C synthase (DACS)variant P72L/T90A/A311V (CefFTM)Streptomyces clavuligeruscephalosporin G0.1222.580.0473pH 7.8, 25 °CPMID 27084018Open
deacetylcephalosporin C synthase (DACS)variant P72L/T90A/A311V/A40V/M229I/T273A (CefFM)Streptomyces clavuligeruscephalosporin G0.3264.640.07033pH 7.8, 25 °CPMID 27084018Open
deacetylcephalosporin C synthase (DACS)variant P72L/T90A/A311V/A40V/M229I/T273A/V171L/R182W/F267L (CefFOS, expressed from the codon-optimized gene cefFOS)Streptomyces clavuligeruscephalosporin G2.3029.20.2502pH 7.8, 25 °CPMID 27084018Open
deacetylcephalosporin C synthase (DACS)variant P72L/T90A/A311V/A40V/M229I/T273A/V171L/R182W/F267L (CefFS)Streptomyces clavuligeruscephalosporin G1.8057.240.2493pH 7.8, 25 °CPMID 27084018Open
deacetylcephalosporin C synthase (DACS)variant P72L/T90A/A311V/A40V/M229I/T273A/V171L/R182W/F267L/G108D (CefFGOS)Streptomyces clavuligeruscephalosporin G1.8994.410.4306pH 7.8, 25 °CPMID 27084018Open