EC 1.14.13.92: phenylacetone monooxygenase
OxidoreductasesOpen in Browse
CatLog read 45 records for EC 1.14.13.92 from 4 papers, for 2 organisms. Names in these papers: phenylacetone monooxygenase, phenylacetone monooxygenase (PAMO), EtaA (ethionamide monooxygenase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 29 records for EC 1.14.13.92 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.13.92 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca | Thermobifida fusca | 32 |
| The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase | Mycobacterium tuberculosis | 6 |
| doi:10.1016/j.catcom.2018.10.022 | Thermobifida fusca | 5 |
| Spatial requirement for PAMO for transformation of non-native linear substrates | Thermobifida fusca | 2 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| EtaA (ethionamide monooxygenase) | Mycobacterium tuberculosis | 2-Dodecanone | 0.023 | 0.2 | 0.12 calc. | pH 8.5, 25 °C | PMID 14610090 | Open record: EtaA (ethionamide monooxygenase), 2-Dodecanone |
| EtaA (ethionamide monooxygenase) | Mycobacterium tuberculosis | Benzylacetone | 0.021 | 0.52 | 0.040 calc. | pH 8.5, 25 °C | PMID 14610090 | Open record: EtaA (ethionamide monooxygenase), Benzylacetone |
| EtaA (ethionamide monooxygenase) | Mycobacterium tuberculosis | Ethionamide | 0.027 | 0.34 | 0.079 calc. | pH 8.5, 25 °C | PMID 14610090 | Open record: EtaA (ethionamide monooxygenase), Ethionamide |
| EtaA (ethionamide monooxygenase) | Mycobacterium tuberculosis | NADPH | — | 0.01 | — | pH 8.5, 25 °C | PMID 14610090 | Open record: EtaA (ethionamide monooxygenase), NADPH |
| EtaA (ethionamide monooxygenase) | Mycobacterium tuberculosis | Phenylacetone | 0.017 | 0.061 | 0.28 calc. | pH 8.5, 25 °C | PMID 14610090 | Open record: EtaA (ethionamide monooxygenase), Phenylacetone |
| EtaA (ethionamide monooxygenase) | Mycobacterium tuberculosis | phenylacetone | 0.26 | 0.28 | 0.93 calc. | pH 8.5, 25 °C | PMID 14610090 | Open record: EtaA (ethionamide monooxygenase), phenylacetone |
| phenylacetone monooxygenase | Thermobifida fusca | NADH | 0.39 | 0.56 | 0.7 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase, NADH |
| phenylacetone monooxygenase | Thermobifida fusca | NADPH | 3.1 | 7 × 10⁻⁴ | 4 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase, NADPH |
| phenylacetone monooxygenasevariant H220A | Thermobifida fusca | NADH | 0.51 | 0.51 | 1 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220A, NADH |
| phenylacetone monooxygenasevariant H220A | Thermobifida fusca | NADPH | 3.3 | 7 × 10⁻⁴ | 5 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220A, NADPH |
| phenylacetone monooxygenasevariant H220D | Thermobifida fusca | NADH | 0.76 | 0.78 | 0.97 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220D, NADH |
| phenylacetone monooxygenasevariant H220D | Thermobifida fusca | NADPH | 1.2 | 0.036 | 33 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220D, NADPH |
| phenylacetone monooxygenasevariant H220E | Thermobifida fusca | NADH | 0.28 | 0.71 | 0.39 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220E, NADH |
| phenylacetone monooxygenasevariant H220E | Thermobifida fusca | NADPH | 1.2 | 0.17 | 7 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220E, NADPH |
| phenylacetone monooxygenasevariant H220F | Thermobifida fusca | NADH | 0.25 | 0.75 | 0.33 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220F, NADH |
| phenylacetone monooxygenasevariant H220F | Thermobifida fusca | NADPH | 1.9 | 0.02 | 95 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220F, NADPH |
| phenylacetone monooxygenasevariant H220N | Thermobifida fusca | NADH | 0.59 | 0.26 | 2.3 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220N, NADH |
| phenylacetone monooxygenasevariant H220N | Thermobifida fusca | NADPH | 3.6 | 6 × 10⁻⁴ | 6 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220N, NADPH |
| phenylacetone monooxygenasevariant H220Q | Thermobifida fusca | NADH | 0.35 | 0.15 | 2.3 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220Q, NADH |
| phenylacetone monooxygenasevariant H220Q | Thermobifida fusca | NADPH | 2.7 | 0.0017 | 1.6 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220Q, NADPH |
| phenylacetone monooxygenasevariant H220Q/K336H | Thermobifida fusca | NADH | 0.67 | 2.4 | 0.28 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220Q/K336H, NADH |
| phenylacetone monooxygenasevariant H220Q/K336H | Thermobifida fusca | NADPH | 1.9 | 0.011 | 170 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220Q/K336H, NADPH |
| phenylacetone monooxygenasevariant H220Q/K336N | Thermobifida fusca | NADH | 0.36 | 0.81 | 0.44 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220Q/K336N, NADH |
| phenylacetone monooxygenasevariant H220Q/K336N | Thermobifida fusca | NADPH | 1 | 0.0024 | 420 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220Q/K336N, NADPH |
| phenylacetone monooxygenasevariant H220T | Thermobifida fusca | NADH | 0.43 | 0.8 | 0.54 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220T, NADH |
| phenylacetone monooxygenasevariant H220T | Thermobifida fusca | NADPH | 2.9 | 0.0017 | 1.7 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220T, NADPH |
| phenylacetone monooxygenasevariant H220W | Thermobifida fusca | NADH | 0.19 | 0.86 | 0.22 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220W, NADH |
| phenylacetone monooxygenasevariant H220W | Thermobifida fusca | NADPH | 0.8 | 0.0023 | 300 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant H220W, NADPH |
| phenylacetone monooxygenasevariant K336H | Thermobifida fusca | NADH | 0.22 | 1.1 | 0.2 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant K336H, NADH |
| phenylacetone monooxygenasevariant K336H | Thermobifida fusca | NADPH | 1.2 | 0.011 | 110 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant K336H, NADPH |
| phenylacetone monooxygenasevariant K336N | Thermobifida fusca | NADH | 0.39 | 0.91 | 0.43 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant K336N, NADH |
| phenylacetone monooxygenasevariant K336N | Thermobifida fusca | NADPH | 1.6 | 0.0011 | 1.5 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant K336N, NADPH |
| phenylacetone monooxygenasevariant R217A | Thermobifida fusca | NADH | 0.25 | 1.9 | 0.13 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant R217A, NADH |
| phenylacetone monooxygenasevariant R217A | Thermobifida fusca | NADPH | 2.2 | 0.32 | 7 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant R217A, NADPH |
| phenylacetone monooxygenasevariant R217L | Thermobifida fusca | NADH | 0.22 | 1.44 | 0.15 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant R217L, NADH |
| phenylacetone monooxygenasevariant R217L | Thermobifida fusca | NADPH | 0.8 | 0.85 | 1 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant R217L, NADPH |
| phenylacetone monooxygenasevariant T218A | Thermobifida fusca | NADH | 0.76 | 1.11 | 0.68 | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant T218A, NADH |
| phenylacetone monooxygenasevariant T218A | Thermobifida fusca | NADPH | 3.8 | 0.0014 | 2.7 × 10³ | pH 7.5, 25 °C | PMID 20703875 | Open record: phenylacetone monooxygenase variant T218A, NADPH |
| phenylacetone monooxygenase (PAMO)variant I67A/P440F | Thermobifida fusca | cyclohexanone | 0.1364 | 0.3472 | 0.393 | pH 8, 25 °C | doi:10.1016/j.catcom.2018.10.022 | Open record: phenylacetone monooxygenase (PAMO) variant I67A/P440F, cyclohexanone |
| phenylacetone monooxygenase (PAMO)variant I67C/P440F | Thermobifida fusca | cyclohexanone | 0.198 | 0.4412 | 0.449 | pH 8, 25 °C | doi:10.1016/j.catcom.2018.10.022 | Open record: phenylacetone monooxygenase (PAMO) variant I67C/P440F, cyclohexanone |
| phenylacetone monooxygenase (PAMO)variant I67G/P440F | Thermobifida fusca | cyclohexanone | 0.1324 | 0.2595 | 0.51 | pH 8, 25 °C | doi:10.1016/j.catcom.2018.10.022 | Open record: phenylacetone monooxygenase (PAMO) variant I67G/P440F, cyclohexanone |
| phenylacetone monooxygenase (PAMO)variant I67Y/P440F | Thermobifida fusca | cyclohexanone | 0.0456 | 0.2107 | 0.216 | pH 8, 25 °C | doi:10.1016/j.catcom.2018.10.022 | Open record: phenylacetone monooxygenase (PAMO) variant I67Y/P440F, cyclohexanone |
| phenylacetone monooxygenase (PAMO)variant P440F | Thermobifida fusca | cyclohexanone | 0.0653 | 0.1037 | 0.633 | pH 8, 25 °C | doi:10.1016/j.catcom.2018.10.022 | Open record: phenylacetone monooxygenase (PAMO) variant P440F, cyclohexanone |
| phenylacetone monooxygenase (PAMO)variant R258A | Thermobifida fusca | 2-octanone | 0.091 | 2.1 | 0.043 | pH 7.4, 25 °C | PMID 29318252 | Open record: phenylacetone monooxygenase (PAMO) variant R258A, 2-octanone |
| phenylacetone monooxygenase (PAMO)variant R258M | Thermobifida fusca | 2-octanone | 0.067 | 0.3 | 0.23 | pH 7.4, 25 °C | PMID 29318252 | Open record: phenylacetone monooxygenase (PAMO) variant R258M, 2-octanone |