CatLogenzyme kinetics catalog

EC 1.14.19.8: pentalenolactone synthase

OxidoreductasesOpen in Browse

CatLog read 7 records for EC 1.14.19.8 from 1 paper, for 1 organism. Names in these papers: PntM (CYP161C2).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 5 records for EC 1.14.19.8 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.14.19.8 in Browse.

Papers

PaperOrganismsRecords
The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines MechanismStreptomyces arenae7

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
PntM (CYP161C2)Streptomyces arenaepentalenolactone F0.030.0360.83pH 8, 30 °CPMID 27588339Open
PntM (CYP161C2)variant F232AStreptomyces arenaepentalenolactone F5.8 × 10⁻⁴0.0430.0137pH 8, 30 °CPMID 27588339Open
PntM (CYP161C2)variant F232LStreptomyces arenaepentalenolactone F0.00150.0120.125pH 8, 30 °CPMID 27588339Open
PntM (CYP161C2)variant M77SStreptomyces arenaepentalenolactone F3.2 × 10⁻⁴0.0190.017pH 8, 30 °CPMID 27588339Open
PntM (CYP161C2)variant M81AStreptomyces arenaepentalenolactone F6.7 × 10⁻⁵0.0370.0062pH 8, 30 °CPMID 27588339Open
PntM (CYP161C2)variant M81CStreptomyces arenaepentalenolactone F0.001530.0190.082pH 8, 30 °CPMID 27588339Open
PntM (CYP161C2)variant M81C-BMEStreptomyces arenaepentalenolactone F0.001420.280.005pH 8, 30 °CPMID 27588339Open