CatLogenzyme kinetics catalog

EC 1.17.4.2: ribonucleoside-triphosphate reductase (thioredoxin)

OxidoreductasesOpen in Browse

CatLog read 15 records for EC 1.17.4.2 from 1 paper, for 1 organism. Names in these papers: ribonucleoside triphosphate reductase.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 26 records for EC 1.17.4.2 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.17.4.2 in Browse.

Papers

PaperOrganismsRecords
Cobamides and ribonucleotide reduction. V. A kinetic study of the ribonucleoside triphosphate reductase of Lactobacillus leichmanniiLactobacillus leichmannii15

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
ribonucleoside triphosphate reductaseLactobacillus leichmannii5'-deoxyadenosylcobalamin2 mM GTP; cobamide coenzyme varied; cosubstrate GTP—8 × 10⁻⁴—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmannii5'-deoxyadenosylcobalamin1.0 mM GTP; DBC coenzyme varied 0.2-2 µM; cosubstrate GTP—9 × 10⁻⁴—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmannii5'-deoxyadenosylcobalamin0.1 mM GTP; DBC coenzyme varied 0.2-2 µM; cosubstrate GTP—0.0028—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmannii5'-deoxyadenosylcobalamin2 mM CTP; no deoxyribonucleotide activator; cosubstrate CTP—0.0055—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmannii5'-deoxyadenosylcobalamin2 mM ATP; no deoxyribonucleotide activator; cosubstrate ATP—0.0083—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmannii5'-deoxyadenosylcobalamin8 µM thioredoxin; 12 µg thioredoxin reductase—4.5 × 10⁻⁴—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniiadenosine 5'-triphosphate40 µM DBC coenzyme; no deoxyribonucleotide activator—0.8—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniiadenosine 5'-triphosphate4 µM DBC coenzyme; with 1 mM dGTP (activator); ATP varied—0.22—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniiadenosyl-5'-deoxyadenosylcobamide—0.0028—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniianilide of 5'-deoxyadenosylcobalamin—0.0033—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniibenzimidazolyl-5'-deoxyadenosylcobamide—8 × 10⁻⁴—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniicytidine 5'-triphosphate40 µM DBC coenzyme; no deoxyribonucleotide activator—0.36—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniicytidine 5'-triphosphate13 µM thioredoxin; 15 µg thioredoxin reductase; CTP varied—0.13—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniiguanosine 5'-triphosphate—0.24—pH 7.5, 37 °CPMID 4381877Open
ribonucleoside triphosphate reductaseLactobacillus leichmanniithioredoxin (E. coli)—0.004—pH 7.5, 37 °CPMID 4381877Open