EC 1.21.3.1: isopenicillin-N synthase
OxidoreductasesOpen in Browse
CatLog read 5 records for EC 1.21.3.1 from 1 paper, for 1 organism. Names in these papers: isopenicillin N synthase (IPNS).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 4 records for EC 1.21.3.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.21.3.1 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| The functional role of cysteines in isopenicillin N synthase. Correlation of cysteine reactivities toward sulfhydryl reagents with kinetic properties of cysteine mutants | Cephalosporium acremonium | 5 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| isopenicillin N synthase (IPNS) | Cephalosporium acremonium | delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine | 3.2 | 0.37 | 8.6 | pH 7.1, 25 °C | PMID 2050677 | Open record: isopenicillin N synthase (IPNS), delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine |
| isopenicillin N synthase (IPNS) | Cephalosporium acremonium | delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valinerecombinant | 4.6 | 0.56 | 8.2 | pH 7.1, 25 °C | PMID 2050677 | Open record: isopenicillin N synthase (IPNS), delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine |
| isopenicillin N synthase (IPNS)variant C106S | Cephalosporium acremonium | delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine | 1.7 | 7.8 | 0.2 | pH 7.1, 25 °C | PMID 2050677 | Open record: isopenicillin N synthase (IPNS) variant C106S, delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine |
| isopenicillin N synthase (IPNS)variant C106S/C255S | Cephalosporium acremonium | delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine | 1.7 | 7.82 | 0.2 | pH 7.1, 25 °C | PMID 2050677 | Open record: isopenicillin N synthase (IPNS) variant C106S/C255S, delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine |
| isopenicillin N synthase (IPNS)variant C255S | Cephalosporium acremonium | delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine | 3.1 | 0.78 | 4 | pH 7.1, 25 °C | PMID 2050677 | Open record: isopenicillin N synthase (IPNS) variant C255S, delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine |