EC 1.4.1.4: glutamate dehydrogenase (NADP+)

OxidoreductasesOpen in Browse

CatLog read 109 records for EC 1.4.1.4 from 9 papers, for 8 organisms. Names in these papers: NADP+-glutamate dehydrogenase, NADP+-dependent glutamate dehydrogenase (EcGDH), glutamate dehydrogenase (CgGDH), NADP-glutamate dehydrogenase (AnGDH) and 7 more.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 284 records for EC 1.4.1.4 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.4.1.4 in Browse.

Papers

Papers with records for EC 1.4.1.4
Paper	Organisms	Records
Importance of lysine-286 at the NADP site of glutamate dehydrogenase from Salmonella typhimurium	Salmonella typhimurium	49
Structure of NADP(+)-dependent glutamate dehydrogenase from Escherichia coli--reflections on the basis of coenzyme specificity in the family of glutamate dehydrogenases	Escherichia coli	11
Mixed disulfide formation at Cys141 leads to apparent unidirectional attenuation of Aspergillus niger NADP-glutamate dehydrogenase activity	Aspergillus niger	10
Crystal structure of the 2-iminoglutarate-bound complex of glutamate dehydrogenase from Corynebacterium glutamicum	Corynebacterium glutamicum	10
Purification and properties of three NAD(P)+ isozymes of L-glutamate dehydrogenase of Chlamydomonas reinhardtii	Chlamydomonas reinhardtii	9
Propylselen inhibits cancer cell growth by targeting glutamate dehydrogenase at the NADP⁺ binding site	Escherichia coli	8
Biochemical characterization of two glutamate dehydrogenases with different cofactor specificities from a hyperthermophilic archaeon Pyrobaculum calidifontis	Pyrobaculum calidifontis	5
Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2	Plasmodium falciparum	4
Glutamate dehydrogenase (RocG) in Bacillus licheniformis WX-02: Enzymatic properties and specific functions in glutamic acid synthesis for poly-γ-glutamic acid production	Bacillus licheniformis	3

Records

Records for EC 1.4.1.4 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
glutamate dehydrogenase (CgGDH)	Corynebacterium glutamicum	2-oxoglutarate	2.5 × 10³	0.89	2.8 × 10³	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH), 2-oxoglutarate
glutamate dehydrogenase (CgGDH)	Corynebacterium glutamicum	ammonium	3.4 × 10³	33	100	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH), ammonium
glutamate dehydrogenase (CgGDH)	Corynebacterium glutamicum	glutamate	9.3	50	0.19	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH), glutamate
glutamate dehydrogenase (CgGDH)	Corynebacterium glutamicum	NADH	1.4	0.16	8.8	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH), NADH
glutamate dehydrogenase (CgGDH)	Corynebacterium glutamicum	NADP+	8.1	0.093	87	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH), NADP+
glutamate dehydrogenase (CgGDH)	Corynebacterium glutamicum	NADPH	2.2 × 10³	0.016	1.3 × 10⁵	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH), NADPH
glutamate dehydrogenase (CgGDH)variant K136A	Corynebacterium glutamicum	NADH	2.3	0.69	3.3	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH) variant K136A, NADH
glutamate dehydrogenase (CgGDH)variant K136A	Corynebacterium glutamicum	NADPH	1.9 × 10³	0.058	3.4 × 10⁴	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH) variant K136A, NADPH
glutamate dehydrogenase (CgGDH)variant R290A	Corynebacterium glutamicum	NADPH	3 × 10³	0.073	4.2 × 10⁴	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH) variant R290A, NADPH
glutamate dehydrogenase (CgGDH)variant S265A	Corynebacterium glutamicum	NADPH	3.3 × 10³	0.16	2.1 × 10⁴	pH 7, 30 °C	PMID 28486765	Open record: glutamate dehydrogenase (CgGDH) variant S265A, NADPH
glutamate dehydrogenase (GDH)	Escherichia coli	L-glutamic acid	17.1	0.45	38 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH), L-glutamic acid
glutamate dehydrogenase (GDH)	Escherichia coli	nicotinamide adenine dinucleotide phosphate (oxidized)	16.7	0.07	240 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH), nicotinamide adenine dinucleotide phosphate (oxidized)
glutamate dehydrogenase (GDH)variant C321A	Escherichia coli	L-glutamic acid	6.7	0.6	11 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH) variant C321A, L-glutamic acid
glutamate dehydrogenase (GDH)variant C321A	Escherichia coli	nicotinamide adenine dinucleotide phosphate (oxidized)	8.8	0.15	59 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH) variant C321A, nicotinamide adenine dinucleotide phosphate (oxidized)
glutamate dehydrogenase (GDH)variant K341L	Escherichia coli	L-glutamic acid	19.6	0.24	82 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH) variant K341L, L-glutamic acid
glutamate dehydrogenase (GDH)variant K341L	Escherichia coli	nicotinamide adenine dinucleotide phosphate (oxidized)	20.4	0.13	160 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH) variant K341L, nicotinamide adenine dinucleotide phosphate (oxidized)
glutamate dehydrogenase (GDH)variant P320A	Escherichia coli	L-glutamic acid	9.6	0.9	11 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH) variant P320A, L-glutamic acid
glutamate dehydrogenase (GDH)variant P320A	Escherichia coli	nicotinamide adenine dinucleotide phosphate (oxidized)	9.2	0.3	31 calc.	pH 8	PMID 30583861	Open record: glutamate dehydrogenase (GDH) variant P320A, nicotinamide adenine dinucleotide phosphate (oxidized)
glutamate dehydrogenase (RocG)	Bacillus licheniformis	2-oxoglutarate	0.1515	4.727	0.03205	40 °C	PMID 28193334	Open record: glutamate dehydrogenase (RocG), 2-oxoglutarate
glutamate dehydrogenase (RocG)	Bacillus licheniformis	L-glutamate	0.0617	23.30	0.00265	40 °C	PMID 28193334	Open record: glutamate dehydrogenase (RocG), L-glutamate
glutamate dehydrogenase (RocG)	Bacillus licheniformis	NADPH	0.1852	0.111	1.668	40 °C	PMID 28193334	Open record: glutamate dehydrogenase (RocG), NADPH
glutamate dehydrogenase Pcal_1606 (NADP+-dependent)	Pyrobaculum calidifontis	2-Oxoglutarate	95	1.7	56	pH 9, 50 °C	PMID 23508687	Open record: glutamate dehydrogenase Pcal_1606 (NADP+-dependent), 2-Oxoglutarate
glutamate dehydrogenase Pcal_1606 (NADP+-dependent)	Pyrobaculum calidifontis	Ammonia	100	2.2	45	pH 9, 50 °C	PMID 23508687	Open record: glutamate dehydrogenase Pcal_1606 (NADP+-dependent), Ammonia
glutamate dehydrogenase Pcal_1606 (NADP+-dependent)	Pyrobaculum calidifontis	L-Glutamate	13	3.4	3.8	pH 9.5, 50 °C	PMID 23508687	Open record: glutamate dehydrogenase Pcal_1606 (NADP+-dependent), L-Glutamate
glutamate dehydrogenase Pcal_1606 (NADP+-dependent)	Pyrobaculum calidifontis	NADP+	9.9	0.035	280	pH 9.5, 50 °C	PMID 23508687	Open record: glutamate dehydrogenase Pcal_1606 (NADP+-dependent), NADP+
glutamate dehydrogenase Pcal_1606 (NADP+-dependent)	Pyrobaculum calidifontis	NADPH	92	0.017	5.4 × 10³	pH 9, 50 °C	PMID 23508687	Open record: glutamate dehydrogenase Pcal_1606 (NADP+-dependent), NADPH
NAD(P)+-glutamate dehydrogenase isozyme GDH1	Chlamydomonas reinhardtii	2-oxoglutarate	—	1.54	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH1, 2-oxoglutarate
NAD(P)+-glutamate dehydrogenase isozyme GDH1	Chlamydomonas reinhardtii	ammonium	—	36	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH1, ammonium
NAD(P)+-glutamate dehydrogenase isozyme GDH1	Chlamydomonas reinhardtii	NADPH	—	0.27	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH1, NADPH
NAD(P)+-glutamate dehydrogenase isozyme GDH2	Chlamydomonas reinhardtii	2-oxoglutarate	—	1.85	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH2, 2-oxoglutarate
NAD(P)+-glutamate dehydrogenase isozyme GDH2	Chlamydomonas reinhardtii	ammonium	—	53	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH2, ammonium
NAD(P)+-glutamate dehydrogenase isozyme GDH2	Chlamydomonas reinhardtii	NADPH	—	0.78	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH2, NADPH
NAD(P)+-glutamate dehydrogenase isozyme GDH3	Chlamydomonas reinhardtii	2-oxoglutarate	—	1.73	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH3, 2-oxoglutarate
NAD(P)+-glutamate dehydrogenase isozyme GDH3	Chlamydomonas reinhardtii	ammonium	—	41	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH3, ammonium
NAD(P)+-glutamate dehydrogenase isozyme GDH3	Chlamydomonas reinhardtii	NADPH	—	0.46	—	pH 7.7, 37 °C	PMID 1540636	Open record: NAD(P)+-glutamate dehydrogenase isozyme GDH3, NADPH
NADP+-dependent glutamate dehydrogenase (EcGDH)	Escherichia coli	NAD+	2.2	21.68	0.102	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH), NAD+
NADP+-dependent glutamate dehydrogenase (EcGDH)	Escherichia coli	NADP+	37.3	—	—	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH), NADP+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q	Escherichia coli	NADP+	34.2	0.129	265	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q, NADP+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q/R289Q/R292Q	Escherichia coli	NAD+	3.9	24.19	0.161	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q/R289Q/R292Q, NAD+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q/R289Q/R292Q	Escherichia coli	NADP+	24	0.929	25.8	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q/R289Q/R292Q, NADP+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q/R289Q/R292Q/S264L	Escherichia coli	NAD+	2.3	19.48	0.118	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q/R289Q/R292Q/S264L, NAD+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q/R289Q/R292Q/S264L	Escherichia coli	NADP+	2.5	19.06	0.131	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q/R289Q/R292Q/S264L, NADP+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q/R289Q/R292Q/S264L/S240A	Escherichia coli	NAD+	3.4	13.74	0.248	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q/R289Q/R292Q/S264L/S240A, NAD+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant K286Q/R289Q/R292Q/S264L/S240A	Escherichia coli	NADP+	6.9	18.3	0.377	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant K286Q/R289Q/R292Q/S264L/S240A, NADP+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant R289Q	Escherichia coli	NADP+	37.6	—	—	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant R289Q, NADP+
NADP+-dependent glutamate dehydrogenase (EcGDH)variant R292Q	Escherichia coli	NADP+	47.3	—	—	pH 8	PMID 23879525	Open record: NADP+-dependent glutamate dehydrogenase (EcGDH) variant R292Q, NADP+
NADP+-glutamate dehydrogenase	Salmonella typhimurium	ammonium chloride	—	3.6	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, ammonium chloride
NADP+-glutamate dehydrogenase	Salmonella typhimurium	ammonium chloride	—	9.4	—	pH 6.9, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, ammonium chloride
NADP+-glutamate dehydrogenase	Salmonella typhimurium	NADH	20.3	2	10.3	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, NADH
NADP+-glutamate dehydrogenase	Salmonella typhimurium	α-ketoglutarate	—	0.27	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, α-ketoglutarate
NADP+-glutamate dehydrogenase	Salmonella typhimurium	α-ketoglutarate	—	0.049	—	pH 6.9, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, α-ketoglutarate
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formkcat(av) = average of kcat(I) and kcat(II)	190	0.0098	2 × 10⁴	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formcorrected to saturating alpha-ketoglutarate	167	—	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form2 mM alpha-ketoglutarate; 2000 µM NADPH	213	—	—	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formnot to saturating alpha-ketoglutarate; alpha-ketoglutarate	188	—	2 × 10⁴	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0065	—	pH 6.72, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0067	—	pH 7.4, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenase	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0108	—	pH 8.1, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K278Q	Salmonella typhimurium	ammonium chloride	—	2.38	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K278Q, ammonium chloride
NADP+-glutamate dehydrogenasevariant K278Q	Salmonella typhimurium	α-ketoglutarate	—	0.456	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K278Q, α-ketoglutarate
NADP+-glutamate dehydrogenasevariant K278Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	175	0.0103	1.7 × 10⁴	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K278Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	ammonium chloride	—	5.5	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, ammonium chloride
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	NADH	15.8	2.1	7.7	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, NADH
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	α-ketoglutarate	—	1	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, α-ketoglutarate
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formkcat(av) = average of kcat(I) and kcat(II)	313	0.28	1.2 × 10³	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formcorrected to saturating alpha-ketoglutarate	325	—	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form2 mM alpha-ketoglutarate; 2000 µM NADPH	300	—	—	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formnot to saturating alpha-ketoglutarate; alpha-ketoglutarate	197	—	700	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0205	—	pH 5.98, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0226	—	pH 6.31, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0275	—	pH 6.69, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0859	—	pH 7.07, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.171	—	pH 7.38, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.289	—	pH 7.58, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286E	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.85	—	pH 8.08, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286E, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	ammonium chloride	—	8.6	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, ammonium chloride
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	NADH	37.5	2.1	18.3	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, NADH
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	α-ketoglutarate	—	0.69	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, α-ketoglutarate
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formkcat(av) = average of kcat(I) and kcat(II)	327	0.066	5 × 10³	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formcorrected to saturating alpha-ketoglutarate	343	—	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form2 mM alpha-ketoglutarate; 2000 µM NADPH	308	—	—	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formnot to saturating alpha-ketoglutarate; alpha-ketoglutarate	230	—	3.5 × 10³	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0125	—	pH 6.3, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0194	—	pH 6.69, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0193	—	pH 7.02, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0182	—	pH 7.38, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0393	—	pH 7.57, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286Q	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form	—	0.0801	—	pH 8.08, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286Q, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	ammonium chloride	—	3.7	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, ammonium chloride
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	NADH	49.5	1.8	26.7	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, NADH
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	α-ketoglutarate	—	0.68	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, α-ketoglutarate
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formkcat(av) = average of kcat(I) and kcat(II)	475	0.03	1.58 × 10⁴	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formcorrected to saturating alpha-ketoglutarate	547	—	—	pH 7.87, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced form2 mM alpha-ketoglutarate; 2000 µM NADPH	405	—	—	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP+-glutamate dehydrogenasevariant K286R	Salmonella typhimurium	β-nicotinamide adenine dinucleotide phosphate, reduced formnot to saturating alpha-ketoglutarate; alpha-ketoglutarate	302	—	1.02 × 10⁴	pH 8, 25 °C	PMID 1510967	Open record: NADP+-glutamate dehydrogenase variant K286R, β-nicotinamide adenine dinucleotide phosphate, reduced form
NADP-glutamate dehydrogenase (AnGDH)	Aspergillus niger	ammonium	—	1.1	—	pH 8	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH), ammonium
NADP-glutamate dehydrogenase (AnGDH)	Aspergillus niger	L-glutamate	—	30.9	—	pH 9.3	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH), L-glutamate
NADP-glutamate dehydrogenase (AnGDH)	Aspergillus niger	NADP+	—	0.028	—	pH 9.3	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH), NADP+
NADP-glutamate dehydrogenase (AnGDH)	Aspergillus niger	NADPH	—	0.023	—	pH 8	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH), NADPH
NADP-glutamate dehydrogenase (AnGDH)variant C141S	Aspergillus niger	ammonium	—	1.2	—	pH 8	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH) variant C141S, ammonium
NADP-glutamate dehydrogenase (AnGDH)variant C141S	Aspergillus niger	L-glutamate	—	28.6	—	pH 9.3	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH) variant C141S, L-glutamate
NADP-glutamate dehydrogenase (AnGDH)variant C415S	Aspergillus niger	L-glutamate	—	36.8	—	pH 9.3	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH) variant C415S, L-glutamate
NADP-glutamate dehydrogenase (AnGDH)variant FIGDH (2-HED-modified at Cys141)	Aspergillus niger	ammonium	—	2.6	—	pH 8	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH) variant FIGDH (2-HED-modified at Cys141), ammonium
NADP-glutamate dehydrogenase (AnGDH)variant FIGDH (2-HED-modified at Cys141)	Aspergillus niger	NADP+	—	0.022	—	pH 9.3	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH) variant FIGDH (2-HED-modified at Cys141), NADP+
NADP-glutamate dehydrogenase (AnGDH)variant FIGDH (2-HED-modified at Cys141)	Aspergillus niger	NADPH	—	0.044	—	pH 8	PMID 24987966	Open record: NADP-glutamate dehydrogenase (AnGDH) variant FIGDH (2-HED-modified at Cys141), NADPH
PfGDH2 (glutamate dehydrogenase 2)	Plasmodium falciparum	2-oxoglutarate	25	0.2	125	pH 7, 25 °C	PMID 22342964	Open record: PfGDH2 (glutamate dehydrogenase 2), 2-oxoglutarate
PfGDH2 (glutamate dehydrogenase 2)	Plasmodium falciparum	L-glutamate	3.7	0.61	6	pH 8, 25 °C	PMID 22342964	Open record: PfGDH2 (glutamate dehydrogenase 2), L-glutamate
PfGDH2 (glutamate dehydrogenase 2)	Plasmodium falciparum	NADP+	—	0.019	—	pH 8, 25 °C	PMID 22342964	Open record: PfGDH2 (glutamate dehydrogenase 2), NADP+
PfGDH2 (glutamate dehydrogenase 2)	Plasmodium falciparum	NADPH	—	0.007	—	pH 7, 25 °C	PMID 22342964	Open record: PfGDH2 (glutamate dehydrogenase 2), NADPH