EC 1.4.3.6: amine oxidase (copper-containing)
OxidoreductasesOpen in Browse
CatLog read 63 records for EC 1.4.3.6 from 5 papers, for 9 organisms. Names in these papers: copper-containing amine oxidase (AO, TOPA quinone), copper amine oxidase (ECAO), copper-containing amine oxidase (LCAO), AOC3 (vascular adhesion protein-1, VAP-1) and 6 more.
EC 1.4.3.6 is no longer current; BRENDA: “deleted, this was classified on the basis of cofactor content rather than reaction catalysed and is now known to contain two distinct enzyme activities. It has been replaced by two enzymes, EC 1.4.3.21”.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| An important lysine residue in copper/quinone-containing amine oxidases | Bos taurus, Euphorbia characias and 3 more | 18 |
| Amine oxidases from Aspergillus niger: identification of a novel flavin-dependent enzyme | Aspergillus niger | 14 |
| Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue | Escherichia coli | 11 |
| The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase | Homo sapiens | 11 |
| Inactivation of copper-containing amine oxidases by turnover products | Lathyrus cicera | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| AOC2 (retina-specific amine oxidase, hRAO), splice variant 1 | Homo sapiens | 2-phenylethylamine | — | 0.077 | — | PMID 19588076 | Open record: AOC2 (retina-specific amine oxidase, hRAO), splice variant 1, 2-phenylethylamine | |
| AOC2 (retina-specific amine oxidase, hRAO), splice variant 1 | Homo sapiens | benzylamine | — | 0.167 | — | PMID 19588076 | Open record: AOC2 (retina-specific amine oxidase, hRAO), splice variant 1, benzylamine | |
| AOC2 (retina-specific amine oxidase, hRAO), splice variant 1 | Homo sapiens | methylamine | — | 1.7 | — | PMID 19588076 | Open record: AOC2 (retina-specific amine oxidase, hRAO), splice variant 1, methylamine | |
| AOC2 (retina-specific amine oxidase, hRAO), splice variant 1 | Homo sapiens | p-tyramine | — | 0.178 | — | PMID 19588076 | Open record: AOC2 (retina-specific amine oxidase, hRAO), splice variant 1, p-tyramine | |
| AOC2 (retina-specific amine oxidase, hRAO), splice variant 1 | Homo sapiens | tryptamine | — | 0.056 | — | PMID 19588076 | Open record: AOC2 (retina-specific amine oxidase, hRAO), splice variant 1, tryptamine | |
| AOC3 (vascular adhesion protein-1, VAP-1) | Homo sapiens | 2-phenylethylamineCHO | — | 1.94 | — | PMID 19588076 | Open record: AOC3 (vascular adhesion protein-1, VAP-1), 2-phenylethylamine | |
| AOC3 (vascular adhesion protein-1, VAP-1) | Homo sapiens | 2-phenylethylamineHEK293-EBNA | — | 8.34 | — | PMID 19588076 | Open record: AOC3 (vascular adhesion protein-1, VAP-1), 2-phenylethylamine | |
| AOC3 (vascular adhesion protein-1, VAP-1) | Homo sapiens | methylamineCHO | — | 0.67 | — | PMID 19588076 | Open record: AOC3 (vascular adhesion protein-1, VAP-1), methylamine | |
| AOC3 (vascular adhesion protein-1, VAP-1) | Homo sapiens | methylamineHEK293-EBNA | — | 1.02 | — | PMID 19588076 | Open record: AOC3 (vascular adhesion protein-1, VAP-1), methylamine | |
| AOC3 (vascular adhesion protein-1, VAP-1)variant M211V/Y394N/L469G | Homo sapiens | 2-phenylethylamine | — | 0.478 | — | PMID 19588076 | Open record: AOC3 (vascular adhesion protein-1, VAP-1) variant M211V/Y394N/L469G, 2-phenylethylamine | |
| AOC3 (vascular adhesion protein-1, VAP-1)variant M211V/Y394N/L469G | Homo sapiens | methylamine | — | 1.99 | — | PMID 19588076 | Open record: AOC3 (vascular adhesion protein-1, VAP-1) variant M211V/Y394N/L469G, methylamine | |
| bovine serum amine oxidase (BSAO) | Bos taurus | benzylamine | 0.35 | 2.2 | 0.16 | pH 7 | PMID 17433047 | Open record: bovine serum amine oxidase (BSAO), benzylamine |
| bovine serum amine oxidase (BSAO) | Bos taurus | N,N'-bis(3-aminopropyl)-1,4-butanediamine | 1 | 0.1 | 10 | pH 7, 37 °C | PMID 17433047 | Open record: bovine serum amine oxidase (BSAO), N,N'-bis(3-aminopropyl)-1,4-butanediamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 9.6 | 0.00779 | 1.2 × 10³ calc. | pH 5.5, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 11.45 | 0.00228 | 5.02 × 10³ calc. | pH 5.75, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 20.7 | 0.00179 | 1.16 × 10⁴ calc. | pH 6, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 20.77 | 0.00169 | 1.23 × 10⁴ calc. | pH 6.5, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 14.98 | 0.0012 | 1.2 × 10⁴ calc. | pH 7, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 14.32 | 0.0017 | 8.4 × 10³ calc. | pH 7.5, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO) | Escherichia coli | 2-phenylethylamine | 13.68 | 0.00226 | 6.05 × 10³ calc. | pH 8, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO), 2-phenylethylamine |
| copper amine oxidase (ECAO)variant D383E | Escherichia coli | 2-phenylethylamine | 0.01163 | 0.028 | 0.42 calc. | pH 5.5, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO) variant D383E, 2-phenylethylamine |
| copper amine oxidase (ECAO)variant D383E | Escherichia coli | 2-phenylethylamine | 0.012 | 0.00962 | 1.3 calc. | pH 6, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO) variant D383E, 2-phenylethylamine |
| copper amine oxidase (ECAO)variant D383E | Escherichia coli | 2-phenylethylamine | 0.00937 | 0.00247 | 3.79 calc. | pH 7, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO) variant D383E, 2-phenylethylamine |
| copper amine oxidase (ECAO)variant D383E | Escherichia coli | 2-phenylethylamine | 0.00612 | 8.8 × 10⁻⁴ | 7.0 calc. | pH 8, 25 °C | PMID 11985492 | Open record: copper amine oxidase (ECAO) variant D383E, 2-phenylethylamine |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine | 68 | 0.14 | 488 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | 2-phenylethylamine | 137 | 0.12 | 1142 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), 2-phenylethylamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | 5-hydroxytryptamine | 136 | 0.29 | 469 | pH 7.2 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), 5-hydroxytryptamine |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Benzylamine | 37 | 0.24 | 153 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Benzylamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Butylamine | 132 | 0.6 | 220 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Butylamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Dopamine | 135 | 0.6 | 225 | pH 7.2 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Dopamine |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Hexylamine | 159 | 0.2 | 794 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Hexylamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Histamine | 95 | 0.6 | 159 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Histamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Norepinephrine | 65 | 1.05 | 62 | pH 7.2 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Norepinephrine |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Octopamine | 122 | 0.36 | 338 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Octopamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Pentylamine | 142 | 0.35 | 406 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Pentylamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Propylamine | 132 | 1.6 | 82 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Propylamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Tryptamine | 100 | 0.1 | 1004 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Tryptamine | |
| copper-containing amine oxidase (AO, TOPA quinone) | Aspergillus niger | Tyramine | 80 | 0.12 | 667 | PMID 7727530 | Open record: copper-containing amine oxidase (AO, TOPA quinone), Tyramine | |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | 2-(aminomethyl)pyridine | 0.47 | — | 15 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), 2-(aminomethyl)pyridine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Agmatine | 45.9 | — | 94 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Agmatine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Benzylamine | 3.7 | — | 9 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Benzylamine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Cadaverine | 159 | — | 1.6 × 10³ | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Cadaverine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Histamine | 10.3 | — | 13 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Histamine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Putrescine | 262 | — | 970 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Putrescine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Spermidine | 100 | — | 48 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Spermidine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Spermine | 28.3 | — | 45 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Spermine |
| copper-containing amine oxidase (LCAO) | Lathyrus cicera | Tyramine | 32.9 | — | 11 | pH 7.2, 25 °C | PMID 14686927 | Open record: copper-containing amine oxidase (LCAO), Tyramine |
| Euphorbia characias latex amine oxidase (ELAO) | Euphorbia characias | 1,4-diaminobutane | 38 | 0.2 | 190 | pH 7, 37 °C | PMID 17433047 | Open record: Euphorbia characias latex amine oxidase (ELAO), 1,4-diaminobutane |
| Euphorbia characias latex amine oxidase (ELAO) | Euphorbia characias | benzylamine | 0.18 | 0.4 | 0.45 | pH 7 | PMID 17433047 | Open record: Euphorbia characias latex amine oxidase (ELAO), benzylamine |
| Euphorbia characias latex amine oxidase (ELAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Euphorbia characias | 1,4-diaminobutane | 13.3 | 1.9 | 7 | pH 7, 37 °C | PMID 17433047 | Open record: Euphorbia characias latex amine oxidase (ELAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), 1,4-diaminobutane |
| Euphorbia characias latex amine oxidase (ELAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Euphorbia characias | benzylamine | 0.17 | 0.4 | 0.43 | pH 7 | PMID 17433047 | Open record: Euphorbia characias latex amine oxidase (ELAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), benzylamine |
| lentil seedling amine oxidase (LSAO) | Lens esculenta | 1,4-diaminobutane | 155 | 0.24 | 646 | pH 7, 37 °C | PMID 17433047 | Open record: lentil seedling amine oxidase (LSAO), 1,4-diaminobutane |
| lentil seedling amine oxidase (LSAO) | Lens esculenta | benzylamine | 1 | 0.45 | 2.2 | pH 7 | PMID 17433047 | Open record: lentil seedling amine oxidase (LSAO), benzylamine |
| lentil seedling amine oxidase (LSAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Lens esculenta | 1,4-diaminobutane | 62 | 1.4 | 44.2 | pH 7, 37 °C | PMID 17433047 | Open record: lentil seedling amine oxidase (LSAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), 1,4-diaminobutane |
| lentil seedling amine oxidase (LSAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Lens esculenta | benzylamine | 0.9 | 0.46 | 1.95 | pH 7 | PMID 17433047 | Open record: lentil seedling amine oxidase (LSAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), benzylamine |
| pea seedling amine oxidase (PSAO) | Pisum sativum | 1,4-diaminobutane | 140 | 0.2 | 700 | pH 7, 37 °C | PMID 17433047 | Open record: pea seedling amine oxidase (PSAO), 1,4-diaminobutane |
| pea seedling amine oxidase (PSAO) | Pisum sativum | benzylamine | 0.5 | 0.45 | 1.1 | pH 7 | PMID 17433047 | Open record: pea seedling amine oxidase (PSAO), benzylamine |
| pea seedling amine oxidase (PSAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Pisum sativum | 1,4-diaminobutane | 53.2 | 1.5 | 35.5 | pH 7, 37 °C | PMID 17433047 | Open record: pea seedling amine oxidase (PSAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), 1,4-diaminobutane |
| pea seedling amine oxidase (PSAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Pisum sativum | benzylamine | 0.5 | 0.45 | 1.1 | pH 7 | PMID 17433047 | Open record: pea seedling amine oxidase (PSAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), benzylamine |
| pig kidney amine oxidase (PKAO) | Sus scrofa | 1,5-diaminopentane | 4.5 | 0.1 | 45 | pH 7, 37 °C | PMID 17433047 | Open record: pig kidney amine oxidase (PKAO), 1,5-diaminopentane |
| pig kidney amine oxidase (PKAO) | Sus scrofa | benzylamine | 0.23 | 0.12 | 1.91 | pH 7 | PMID 17433047 | Open record: pig kidney amine oxidase (PKAO), benzylamine |
| pig kidney amine oxidase (PKAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Sus scrofa | 1,5-diaminopentane | 0.9 | 0.23 | 3.9 | pH 7, 37 °C | PMID 17433047 | Open record: pig kidney amine oxidase (PKAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), 1,5-diaminopentane |
| pig kidney amine oxidase (PKAO)variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed) | Sus scrofa | benzylamine | 0.046 | 0.25 | 0.18 | pH 7 | PMID 17433047 | Open record: pig kidney amine oxidase (PKAO) variant xenon-treated (exposed to 10 atm xenon gas, then exhaustively dialysed), benzylamine |