CatLogenzyme kinetics catalog

EC 1.5.1.34: 6,7-dihydropteridine reductase

OxidoreductasesOpen in Browse

CatLog read 20 records for EC 1.5.1.34 from 2 papers, for 2 organisms. Names in these papers: nitroreductase (NTR), LmQDPR (quinonoid dihydropteridine reductase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 81 records for EC 1.5.1.34 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.5.1.34 in Browse.

Papers

PaperOrganismsRecords
Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzymeEscherichia coli18
Dissecting the metabolic roles of pteridine reductase 1 in Trypanosoma brucei and Leishmania majorLeishmania major2

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
LmQDPR (quinonoid dihydropteridine reductase)Leishmania majorquinonoid 6,7-dimethyl-7,8-dihydropterin22.70.02281 × 10³pH 7.4, 25 °CPMID 21239486Open
LmQDPR (quinonoid dihydropteridine reductase)Leishmania majorquinonoid 7,8-dihydrobiopterin16.20.004123.9 × 10³pH 7.4, 25 °CPMID 21239486Open
nitroreductase (NTR)Escherichia coli2-Nitrofuranfixed NADH at 60 μM; cosubstrate NADH4.30.459.6 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coli2-Nitrofuranfixed NADPH at 60 μM; cosubstrate NADPH4.50.479.6 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coli2-Nitrosotoluene——610pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coli2-Nitrotoluene0.2110.0201pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADHfixed nitrofurazone at 750 μM; cosubstrate nitrofurazone110.0061.8 × 10³ calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADHfixed nitrofurantoin at 750 μM; cosubstrate nitrofurantoin11.50.0081.4 × 10³ calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADHfixed 2-nitrofuran at 1 mM; initial rate monitored at 340 nm4.30.0031.4 × 10³ calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADHreaction followed at 440 nm; cosubstrate nitrofurazone—0.35—pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADPHfixed nitrofurazone at 750 μM; cosubstrate nitrofurazone11.30.0071.6 × 10³ calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADPHfixed nitrofurantoin at 750 μM; cosubstrate nitrofurantoin11.70.0081.5 × 10³ calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNADPHfixed 2-nitrofuran at 1 mM; initial rate monitored at 340 nm4.30.0031.4 × 10³ calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNitrobenzene——0.65pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNitrofurantoinfixed NADH at 60 μM; cosubstrate NADH11.20.1959 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNitrofurantoinfixed NADPH at 60 μM; cosubstrate NADPH10.70.1667 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNitrofurazonefixed NADH at 60 μM; cosubstrate NADH10.70.1667 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNitrofurazonefixed NADPH at 60 μM; cosubstrate NADPH10.50.1762 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia colinitrofurazone2251.85122 calc.pH 7, 25 °CPMID 15684426Open
nitroreductase (NTR)Escherichia coliNitrosobenzene1670.01091.52 × 10⁴pH 7, 25 °CPMID 15684426Open