EC 1.6.3.1: NAD(P)H oxidase (H2O2-forming)

OxidoreductasesOpen in Browse

CatLog read 16 records for EC 1.6.3.1 from 2 papers, for 1 organism. Names in these papers: MICAL1 (full-length), MICAL1 MOCH (flavoprotein + CH domains), MICAL1 MOCHLIM (flavoprotein + CH + LIM domains), FMO5.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 14 records for EC 1.6.3.1 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.6.3.1 in Browse.

Papers

Papers with records for EC 1.6.3.1
Paper	Organisms	Records
Properties and catalytic activities of MICAL1, the flavoenzyme involved in cytoskeleton dynamics, and modulation by its CH, LIM and C-terminal domains	Homo sapiens	15
The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion	Homo sapiens	1

Records

Records for EC 1.6.3.1 read from the paper
Enzyme	Organism	Substrate	k_cat (s⁻¹)	K_m (mM)	k_cat/K_m (mM⁻¹ s⁻¹)	Conditions	Paper	Open record
FMO5	Homo sapiens	fenthion	—	0.249	—	pH 7.4, 37 °C	PMID 18845175	Open record: FMO5, fenthion
MICAL1 (full-length)	Homo sapiens	F-actin (filamentous rabbit skeletal muscle actin, Cytoskeleton AKL99)	7.8	0.029	276	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 (full-length), F-actin (filamentous rabbit skeletal muscle actin, Cytoskeleton AKL99)
MICAL1 (full-length)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)NADPH oxidase reaction (H2O2-producing)	0.28	0.375	0.75	pH 7, 25 °C	PMID 26845023	Open record: MICAL1 (full-length), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 (full-length)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)NADPH oxidase reaction; whole data set fitted to Eq. (6)	0.3	0.398	0.73	pH 7, 25 °C	PMID 26845023	Open record: MICAL1 (full-length), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 (full-length)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)no F-actin; NADPH varied 100–700 μM; enzyme 1250 nM	0.8	4.652	0.17	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 (full-length), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 (full-length)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)F-actin fixed at 4.3 μM; NADPH varied 10–400 μM	1.9	0.029	64.8	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 (full-length), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCH (flavoprotein + CH domains)	Homo sapiens	F-actin (filamentous rabbit skeletal muscle actin, Cytoskeleton AKL99)	26	0.0027	9487	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 MOCH (flavoprotein + CH domains), F-actin (filamentous rabbit skeletal muscle actin, Cytoskeleton AKL99)
MICAL1 MOCH (flavoprotein + CH domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)NADPH oxidase reaction (H2O2-producing)	2.5	0.134	18.5	pH 7, 25 °C	PMID 26845023	Open record: MICAL1 MOCH (flavoprotein + CH domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCH (flavoprotein + CH domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)NADPH oxidase reaction; whole data set fitted to Eq. (6)	2.6	0.111	23.2	pH 7, 25 °C	PMID 26845023	Open record: MICAL1 MOCH (flavoprotein + CH domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCH (flavoprotein + CH domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)no F-actin; NADPH varied 10–500 μM; enzyme 190 nM	1.7	0.459	3.8	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 MOCH (flavoprotein + CH domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCH (flavoprotein + CH domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)F-actin fixed at 4.2 μM; NADPH varied 10–200 μM; enzyme 3 nM	21	0.05	423	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 MOCH (flavoprotein + CH domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCHLIM (flavoprotein + CH + LIM domains)	Homo sapiens	F-actin (filamentous rabbit skeletal muscle actin, Cytoskeleton AKL99)	15	0.0044	3.39 × 10³	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 MOCHLIM (flavoprotein + CH + LIM domains), F-actin (filamentous rabbit skeletal muscle actin, Cytoskeleton AKL99)
MICAL1 MOCHLIM (flavoprotein + CH + LIM domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)NADPH oxidase reaction (H2O2-producing)	3.5	0.23	15.3	pH 7, 25 °C	PMID 26845023	Open record: MICAL1 MOCHLIM (flavoprotein + CH + LIM domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCHLIM (flavoprotein + CH + LIM domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)NADPH oxidase reaction; whole data set fitted to Eq. (6)	2.9	0.178	16.5	pH 7, 25 °C	PMID 26845023	Open record: MICAL1 MOCHLIM (flavoprotein + CH + LIM domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCHLIM (flavoprotein + CH + LIM domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)no F-actin; NADPH varied 25–1000 μM; enzyme 125 nM	4.3	0.966	4.5	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 MOCHLIM (flavoprotein + CH + LIM domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)
MICAL1 MOCHLIM (flavoprotein + CH + LIM domains)	Homo sapiens	nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)F-actin fixed at 4.4 μM; NADPH varied 20–200 μM	6.4	0.014	448	pH 7.7, 25 °C	PMID 26845023	Open record: MICAL1 MOCHLIM (flavoprotein + CH + LIM domains), nicotinamide adenine dinucleotide phosphate, reduced form (NADPH)