EC 1.6.5.5: NADPH:quinone reductase
OxidoreductasesOpen in Browse
CatLog read 62 records for EC 1.6.5.5 from 3 papers, for 3 organisms. Names in these papers: nitroreductase A (NfsA), ζ-crystallin, AntE.
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 54 records for EC 1.6.5.5 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.6.5.5 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Reduction of quinones and nitroaromatic compounds by Escherichia coli nitroreductase A (NfsA): Characterization of kinetics and substrate specificity | Escherichia coli | 31 |
| Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin | Homo sapiens | 22 |
| Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis | Streptomyces sp. NRRL2288 | 9 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| AntE | Streptomyces sp. NRRL2288 | cinnamoyl-coenzyme A | 0.0688 | 0.38 | 0.18 calc. | PMID 26356484 | Open record: AntE, cinnamoyl-coenzyme A | |
| AntE | Streptomyces sp. NRRL2288 | crotonyl-coenzyme A | 0.1755 | 1.58 | 0.111 calc. | PMID 26356484 | Open record: AntE, crotonyl-coenzyme A | |
| AntEvariant A182L | Streptomyces sp. NRRL2288 | crotonyl-coenzyme A | 0.1518 | 1.31 | 0.116 calc. | PMID 26356484 | Open record: AntE variant A182L, crotonyl-coenzyme A | |
| AntEvariant V350A | Streptomyces sp. NRRL2288 | crotonyl-coenzyme A | 0.1197 | 1.21 | 0.0989 calc. | PMID 26356484 | Open record: AntE variant V350A, crotonyl-coenzyme A | |
| AntEvariant V350A | Streptomyces sp. NRRL2288 | p-coumaroyl-coenzyme A | 0.0735 | 0.14 | 0.53 calc. | PMID 26356484 | Open record: AntE variant V350A, p-coumaroyl-coenzyme A | |
| AntEvariant V350F | Streptomyces sp. NRRL2288 | crotonyl-coenzyme A | 0.1263 | 0.49 | 0.26 calc. | PMID 26356484 | Open record: AntE variant V350F, crotonyl-coenzyme A | |
| AntEvariant V350G | Streptomyces sp. NRRL2288 | cinnamoyl-coenzyme A | 0.0877 | 0.089 | 0.99 calc. | PMID 26356484 | Open record: AntE variant V350G, cinnamoyl-coenzyme A | |
| AntEvariant V350G | Streptomyces sp. NRRL2288 | crotonyl-coenzyme A | 0.0675 | 1.17 | 0.0577 calc. | PMID 26356484 | Open record: AntE variant V350G, crotonyl-coenzyme A | |
| AntEvariant V350G | Streptomyces sp. NRRL2288 | p-coumaroyl-coenzyme A | 0.109 | 0.2 | 0.55 calc. | PMID 26356484 | Open record: AntE variant V350G, p-coumaroyl-coenzyme A | |
| nitroreductase A (NfsA) | Escherichia coli | (5-aziridin-1-yl)-2,4-dinitrobenzamide | 15 | 0.23 | 65 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), (5-aziridin-1-yl)-2,4-dinitrobenzamide |
| nitroreductase A (NfsA) | Escherichia coli | 1,4-Benzoquinone | 62 | 0.011 | 5.8 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 1,4-Benzoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 1,4-Dihydroxy-9,10-anthraquinone | 0.7 | 0.007 | 100 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 1,4-Dihydroxy-9,10-anthraquinone |
| nitroreductase A (NfsA) | Escherichia coli | 1,4-Naphthoquinone | 46 | 0.033 | 1.4 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 1,4-Naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 1,8-Dihydroxy-9,10-anthraquinone | 1.6 | 0.015 | 110 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 1,8-Dihydroxy-9,10-anthraquinone |
| nitroreductase A (NfsA) | Escherichia coli | 2,3-Dichloro-1,4-naphthoquinone | 61 | 0.022 | 2.8 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2,3-Dichloro-1,4-naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 2,4,6-trinitrophenyl-N-methylnitraminefixed 100 µM NADPH | 85 | 0.011 | 7.9 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2,4,6-trinitrophenyl-N-methylnitramine |
| nitroreductase A (NfsA) | Escherichia coli | 2,4,6-trinitrophenyl-N-methylnitramineping-pong fit (Eq. 1) with both NADPH and the oxidant varied | 110 | — | — | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2,4,6-trinitrophenyl-N-methylnitramine |
| nitroreductase A (NfsA) | Escherichia coli | 2,4,6-Trinitrotoluene | 89 | 0.033 | 2.7 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2,4,6-Trinitrotoluene |
| nitroreductase A (NfsA) | Escherichia coli | 2,4,6-trinitrotoluene | 135 | — | — | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2,4,6-trinitrotoluene |
| nitroreductase A (NfsA) | Escherichia coli | 2,6-Dimethyl-1,4-benzoquinone | 51 | 0.016 | 3.2 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2,6-Dimethyl-1,4-benzoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 2-Hydroxy-1,4-naphthoquinone | 72 | 0.0066 | 1.1 × 10⁴ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2-Hydroxy-1,4-naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 2-Hydroxy-3-methyl-1,4-naphthoquinone | 56 | 0.0064 | 8.8 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2-Hydroxy-3-methyl-1,4-naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 2-Methyl-1,4-benzoquinone | 54 | 0.008 | 6.8 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2-Methyl-1,4-benzoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 2-Methyl-1,4-naphthoquinone | 36 | 0.13 | 280 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 2-Methyl-1,4-naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 5,8-Dihydroxy-1,4-naphthoquinone | 12 | 9 × 10⁻⁴ | 1.3 × 10⁴ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 5,8-Dihydroxy-1,4-naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 5-Hydroxy-1,4-naphthoquinone | 22 | 0.0016 | 1.4 × 10⁴ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 5-Hydroxy-1,4-naphthoquinone |
| nitroreductase A (NfsA) | Escherichia coli | 9,10-Anthraquinone-2-sulfonic acid | 1.4 | 0.074 | 19 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 9,10-Anthraquinone-2-sulfonic acid |
| nitroreductase A (NfsA) | Escherichia coli | 9,10-Phenantrenequinone | 54 | 0.012 | 4.7 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), 9,10-Phenantrenequinone |
| nitroreductase A (NfsA) | Escherichia coli | m-Dinitrobenzene | 55 | 0.046 | 1.2 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), m-Dinitrobenzene |
| nitroreductase A (NfsA) | Escherichia coli | NADPH | — | — | 3.4 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), NADPH |
| nitroreductase A (NfsA) | Escherichia coli | Nifuroxime | 180 | 0.031 | 5.9 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), Nifuroxime |
| nitroreductase A (NfsA) | Escherichia coli | Nitrobenzene | 14 | 1.5 | 9.6 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), Nitrobenzene |
| nitroreductase A (NfsA) | Escherichia coli | Nitrofurantoin | 136 | 0.019 | 7.2 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), Nitrofurantoin |
| nitroreductase A (NfsA) | Escherichia coli | o-Dinitrobenzene | 60 | 0.018 | 3.4 × 10³ | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), o-Dinitrobenzene |
| nitroreductase A (NfsA) | Escherichia coli | p-Dinitrobenzene | 27 | 0.037 | 740 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), p-Dinitrobenzene |
| nitroreductase A (NfsA) | Escherichia coli | p-Nitroacetophenone | 59 | 0.39 | 150 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), p-Nitroacetophenone |
| nitroreductase A (NfsA) | Escherichia coli | p-Nitrobenzaldehyde | 30 | 0.17 | 180 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), p-Nitrobenzaldehyde |
| nitroreductase A (NfsA) | Escherichia coli | p-Nitrobenzoic acid | 64 | 2.5 | 25 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), p-Nitrobenzoic acid |
| nitroreductase A (NfsA) | Escherichia coli | Riboflavin | 4.2 | 0.016 | 260 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), Riboflavin |
| nitroreductase A (NfsA) | Escherichia coli | Tetramethyl-1,4-benzoquinone | 2.5 | 1.1 | 2.3 | pH 7, 25 °C | PMID 27986535 | Open record: nitroreductase A (NfsA), Tetramethyl-1,4-benzoquinone |
| ζ-crystallin | Homo sapiens | (E)-4-hydroxyhex-2-enal | 1.33 | 0.13 | 10.22 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-4-hydroxyhex-2-enal |
| ζ-crystallin | Homo sapiens | (E)-4-hydroxynon-2-enal | 1.15 | 0.55 | 2.1 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-4-hydroxynon-2-enal |
| ζ-crystallin | Homo sapiens | (E)-hex-2-enal | 0.28 | 5.455 | 0.052 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-hex-2-enal |
| ζ-crystallin | Homo sapiens | (E)-non-2-enal | 0.113 | 0.482 | 0.23 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-non-2-enal |
| ζ-crystallin | Homo sapiens | (E)-non-3-en-2-one | 0.22 | 0.94 | 0.23 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-non-3-en-2-one |
| ζ-crystallin | Homo sapiens | (E)-pent-2-enal | 0.2 | 8.6 | 0.023 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-pent-2-enal |
| ζ-crystallin | Homo sapiens | (E)-pent-3-en-2-one | 0.2 | 0.535 | 0.37 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, (E)-pent-3-en-2-one |
| ζ-crystallin | Homo sapiens | but-3-en-2-one | 0.17 | 0.035 | 4.8 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, but-3-en-2-one |
| ζ-crystallin | Homo sapiens | prop-2-enal | 1.67 | 1.45 | 1.2 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin, prop-2-enal |
| ζ-crystallinvariant Y53F | Homo sapiens | (E)-4-hydroxyhex-2-enal | 0.083 | 3.67 | 0.023 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, (E)-4-hydroxyhex-2-enal |
| ζ-crystallinvariant Y53F | Homo sapiens | (E)-hex-2-enal | 0.13 | 73.27 | 0.0017 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, (E)-hex-2-enal |
| ζ-crystallinvariant Y53F | Homo sapiens | (E)-non-3-en-2-one | 0.05 | 3.11 | 0.017 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, (E)-non-3-en-2-one |
| ζ-crystallinvariant Y53F | Homo sapiens | (E)-pent-3-en-2-one | 0.067 | 2.66 | 0.025 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, (E)-pent-3-en-2-one |
| ζ-crystallinvariant Y53F | Homo sapiens | but-3-en-2-one | 0.13 | 0.97 | 0.13 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, but-3-en-2-one |
| ζ-crystallinvariant Y53F | Homo sapiens | NADPH | — | 0.06 | — | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, NADPH |
| ζ-crystallinvariant Y53F | Homo sapiens | phenanthrene-9,10-dione | 4.67 | 0.01 | 467 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, phenanthrene-9,10-dione |
| ζ-crystallinvariant Y53F | Homo sapiens | prop-2-enal | 2.33 | 39.74 | 0.058 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y53F, prop-2-enal |
| ζ-crystallinvariant Y59F | Homo sapiens | (E)-4-hydroxyhex-2-enal | 2.17 | 1.26 | 1.7 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y59F, (E)-4-hydroxyhex-2-enal |
| ζ-crystallinvariant Y59F | Homo sapiens | (E)-hex-2-enal | 0.37 | 6.12 | 0.067 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y59F, (E)-hex-2-enal |
| ζ-crystallinvariant Y59F | Homo sapiens | but-3-en-2-one | 0.28 | 0.06 | 4.67 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y59F, but-3-en-2-one |
| ζ-crystallinvariant Y59F | Homo sapiens | NADPH | — | 0.015 | — | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y59F, NADPH |
| ζ-crystallinvariant Y59F | Homo sapiens | prop-2-enal | 1.25 | 0.86 | 1.5 | pH 7, 25 °C | PMID 20835842 | Open record: ζ-crystallin variant Y59F, prop-2-enal |