CatLogenzyme kinetics catalog

EC 1.8.1.12: trypanothione-disulfide reductase

OxidoreductasesOpen in Browse

CatLog read 16 records for EC 1.8.1.12 from 1 paper, for 1 organism. Names in these papers: trypanothione reductase.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 31 records for EC 1.8.1.12 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 1.8.1.12 in Browse.

Papers

PaperOrganismsRecords
Mutational analysis of parasite trypanothione reductase: acquisition of glutathione reductase activity in a triple mutantTrypanosoma congolense16

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
trypanothione reductaseTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide880.0253.53 × 10³pH 7.8, 25 °CPMID 2007114Open
trypanothione reductaseTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide1520.0188.42 × 10³pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant A343RTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide280.0093.13 × 10³pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18ATrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide630.266230pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18A/A343RTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide8.250.37522pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18A/W21RTrypanosoma congolenseglutathione disulfide——0.073pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18A/W21RTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide505.29.5pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18A/W21R/A343RTrypanosoma congolenseglutathione disulfideTable III—700.23pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18A/W21R/A343RTrypanosoma congolenseglutathione disulfidein the text16.3——pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant E18A/W21R/A343RTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide304.56.7pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant K483*Trypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide570.0115.15 × 10³pH 7.8, 25 °CPMID 2007114Open
trypanothione reductasevariant P488*Trypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide670.0223.07 × 10³pH 7.8, 25 °CPMID 2007114Open
trypanothione reductasevariant T473*Trypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide880.0125.2 × 10³pH 7.8, 25 °CPMID 2007114Open
trypanothione reductasevariant W21RTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide350.652pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant W21R/A343RTrypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide702.725pH 6.6, 25 °CPMID 2007114Open
trypanothione reductasevariant Y478*Trypanosoma congolenseN1,N8-bis(glutathionyl)spermidine disulfide—0.033—pH 7.8, 25 °CPMID 2007114Open