EC 2.1.1.235: dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

TransferasesOpen in Browse

CatLog read 8 records for EC 2.1.1.235 from 2 papers, for 1 organism. Names in these papers: TylM1 (N,N-dimethyltransferase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

Papers

Papers with records for EC 2.1.1.235
PaperOrganismsRecords
Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamineStreptomyces fradiae5
Molecular architecture of TylM1 from Streptomyces fradiae: an N,N-dimethyltransferase involved in the production of dTDP-D-mycaminoseStreptomyces fradiae3

Records

Records for EC 2.1.1.235 read from the paper
EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaperOpen record
TylM1 (N,N-dimethyltransferase)Streptomyces fradiaedTDP-3-(methylamino)-3,6-dideoxy-alpha-D-glucopyranose0.5420.046811.57pH 7.5, 24 °CPMID 12119032Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-(methylamino)-3,6-dideoxy-alpha-D-glucopyranose
TylM1 (N,N-dimethyltransferase)Streptomyces fradiaedTDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose0.120.11841.013pH 7.5, 24 °CPMID 12119032Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose
TylM1 (N,N-dimethyltransferase)Streptomyces fradiaedTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose0.1650.05942.778pH 7.5, 24 °CPMID 12119032Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose
TylM1 (N,N-dimethyltransferase)Streptomyces fradiaedTDP-3-amino-3,6-dideoxyglucose0.1720.0453.825 °CPMID 21142177Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-amino-3,6-dideoxyglucose
TylM1 (N,N-dimethyltransferase)Streptomyces fradiaeS-adenosyl-L-methionine1.28 mM 7 (saturating); 4.5 µM TylM1; first methylation step0.0920.09890.93 calc.pH 7.5, 24 °CPMID 12119032Open record: TylM1 (N,N-dimethyltransferase), S-adenosyl-L-methionine
TylM1 (N,N-dimethyltransferase)Streptomyces fradiaeS-adenosyl-L-methionine0.89 mM 27; 0.56 µM TylM1; second methylation step0.8570.1177.32 calc.pH 7.5, 24 °CPMID 12119032Open record: TylM1 (N,N-dimethyltransferase), S-adenosyl-L-methionine
TylM1 (N,N-dimethyltransferase)variant H123AStreptomyces fradiaedTDP-3-amino-3,6-dideoxyglucose0.0460.670.06925 °CPMID 21142177Open record: TylM1 (N,N-dimethyltransferase) variant H123A, dTDP-3-amino-3,6-dideoxyglucose
TylM1 (N,N-dimethyltransferase)variant H123NStreptomyces fradiaedTDP-3-amino-3,6-dideoxyglucose0.01260.930.01425 °CPMID 21142177Open record: TylM1 (N,N-dimethyltransferase) variant H123N, dTDP-3-amino-3,6-dideoxyglucose