EC 2.1.1.235: dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
TransferasesOpen in Browse
CatLog read 8 records for EC 2.1.1.235 from 2 papers, for 1 organism. Names in these papers: TylM1 (N,N-dimethyltransferase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
Papers
| Paper | Organisms | Records |
|---|---|---|
| Expression, purification, and characterization of two N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine | Streptomyces fradiae | 5 |
| Molecular architecture of TylM1 from Streptomyces fradiae: an N,N-dimethyltransferase involved in the production of dTDP-D-mycaminose | Streptomyces fradiae | 3 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| TylM1 (N,N-dimethyltransferase) | Streptomyces fradiae | dTDP-3-(methylamino)-3,6-dideoxy-alpha-D-glucopyranose | 0.542 | 0.0468 | 11.57 | pH 7.5, 24 °C | PMID 12119032 | Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-(methylamino)-3,6-dideoxy-alpha-D-glucopyranose |
| TylM1 (N,N-dimethyltransferase) | Streptomyces fradiae | dTDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose | 0.12 | 0.1184 | 1.013 | pH 7.5, 24 °C | PMID 12119032 | Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose |
| TylM1 (N,N-dimethyltransferase) | Streptomyces fradiae | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose | 0.165 | 0.0594 | 2.778 | pH 7.5, 24 °C | PMID 12119032 | Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose |
| TylM1 (N,N-dimethyltransferase) | Streptomyces fradiae | dTDP-3-amino-3,6-dideoxyglucose | 0.172 | 0.045 | 3.8 | 25 °C | PMID 21142177 | Open record: TylM1 (N,N-dimethyltransferase), dTDP-3-amino-3,6-dideoxyglucose |
| TylM1 (N,N-dimethyltransferase) | Streptomyces fradiae | S-adenosyl-L-methionine1.28 mM 7 (saturating); 4.5 µM TylM1; first methylation step | 0.092 | 0.0989 | 0.93 calc. | pH 7.5, 24 °C | PMID 12119032 | Open record: TylM1 (N,N-dimethyltransferase), S-adenosyl-L-methionine |
| TylM1 (N,N-dimethyltransferase) | Streptomyces fradiae | S-adenosyl-L-methionine0.89 mM 27; 0.56 µM TylM1; second methylation step | 0.857 | 0.117 | 7.32 calc. | pH 7.5, 24 °C | PMID 12119032 | Open record: TylM1 (N,N-dimethyltransferase), S-adenosyl-L-methionine |
| TylM1 (N,N-dimethyltransferase)variant H123A | Streptomyces fradiae | dTDP-3-amino-3,6-dideoxyglucose | 0.046 | 0.67 | 0.069 | 25 °C | PMID 21142177 | Open record: TylM1 (N,N-dimethyltransferase) variant H123A, dTDP-3-amino-3,6-dideoxyglucose |
| TylM1 (N,N-dimethyltransferase)variant H123N | Streptomyces fradiae | dTDP-3-amino-3,6-dideoxyglucose | 0.0126 | 0.93 | 0.014 | 25 °C | PMID 21142177 | Open record: TylM1 (N,N-dimethyltransferase) variant H123N, dTDP-3-amino-3,6-dideoxyglucose |