CatLogenzyme kinetics catalog

EC 2.1.1.8: histamine N-methyltransferase

TransferasesOpen in Browse

CatLog read 7 records for EC 2.1.1.8 from 1 paper, for 1 organism. Names in these papers: histamine N-methyltransferase.

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 12 records for EC 2.1.1.8 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.1.1.8 in Browse.

Papers

PaperOrganismsRecords
Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disabilityHomo sapiens7

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
histamine N-methyltransferaseHomo sapienshistamine—0.0019—pH 8, 25 °CPMID 27769936Open
histamine N-methyltransferaseHomo sapiensS-adenosylmethionine0.610.0041150 calc.pH 8, 25 °CPMID 27769936Open
histamine N-methyltransferasevariant L208FHomo sapienshistamine—0.0034—pH 8, 25 °CPMID 27769936Open
histamine N-methyltransferasevariant L208FHomo sapiensS-adenosylmethionine0.110.01248.9 calc.pH 8, 25 °CPMID 27769936Open
histamine N-methyltransferasevariant L208KHomo sapiensS-adenosylmethionine0.030.0152.0 calc.pH 8, 25 °CPMID 27769936Open
histamine N-methyltransferasevariant L208VHomo sapienshistamine—0.0011—pH 8, 25 °CPMID 27769936Open
histamine N-methyltransferasevariant L208VHomo sapiensS-adenosylmethionine0.230.006834 calc.pH 8, 25 °CPMID 27769936Open