CatLogenzyme kinetics catalog

EC 2.3.1.191: UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase

TransferasesOpen in Browse

CatLog read 24 records for EC 2.3.1.191 from 1 paper, for 1 organism. Names in these papers: LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase).

Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.

CatLog also holds 2 records for EC 2.3.1.191 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.191 in Browse.

Papers

PaperOrganismsRecords
Steady-state kinetics and mechanism of LpxD, the N-acyltransferase of lipid A biosynthesisEscherichia coli24

Records

EnzymeOrganismSubstratekcat (s⁻¹)Km (mM)kcat/Km (mM⁻¹ s⁻¹)ConditionsPaper
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)Escherichia coliR-3-hydroxymyristoyl-acyl carrier proteineq. 8 fit230.00327.2 × 10³ calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)Escherichia coliR-3-hydroxymyristoyl-acyl carrier proteinradiolabel TLC assay—0.0032—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)Escherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamineeq. 8 fit—0.0025—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)Escherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamineradiolabel TLC assay—0.0013—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant D232AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein1.90.04740 calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant D232AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.067—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant F41AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein4.10.00351.2 × 10³ calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant F41AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.073—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant H239AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein0.0320.00349.4 calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant H239AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—8.4 × 10⁻⁴—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant H276AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein0.730.0017430 calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant H276AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.0063—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant K194AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein5.70.00381.5 × 10³ calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant K194AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.0056—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant K46AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein170.0121.4 × 10³ calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant K46AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.0071—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant N233AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein1.40.013110 calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant N233AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.028—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant Q236AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein120.013920 calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant Q236AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.0042—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant R293AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein8.90.074120 calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant R293AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.0036—pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant Y47AEscherichia coliR-3-hydroxymyristoyl-acyl carrier protein180.0053.6 × 10³ calc.pH 7.5, 30 °CPMID 18422345Open
LpxD (UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase)variant Y47AEscherichia coliUDP-3-O-(R-3-hydroxymyristoyl)-alpha-D-glucosamine—0.0078—pH 7.5, 30 °CPMID 18422345Open