EC 2.3.1.31: homoserine O-acetyltransferase
TransferasesOpen in Browse
CatLog read 44 records for EC 2.3.1.31 from 3 papers, for 3 organisms. Names in these papers: homoserine transacetylase (metA protein), homoserine transacetylase (HTA), DcsE (L-serine O-acetyltransferase).
Read from the paper by an AI model and checked against the paper by a second, separate AI run; code converted the units.
CatLog also holds 22 records for EC 2.3.1.31 that are not yet re-read: from its earlier version, built from the enzyme databases and partly checked against the papers. All records for EC 2.3.1.31 in Browse.
Papers
| Paper | Organisms | Records |
|---|---|---|
| A single amino acid change is responsible for evolution of acyltransferase specificity in bacterial methionine biosynthesis | Bacillus cereus | 22 |
| Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase | Haemophilus influenzae | 14 |
| Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway | Streptomyces lavendulae | 8 |
Records
| Enzyme | Organism | Substrate | kcat (s⁻¹) | Km (mM) | kcat/Km (mM⁻¹ s⁻¹) | Conditions | Paper | Open record |
|---|---|---|---|---|---|---|---|---|
| DcsE (L-serine O-acetyltransferase) | Streptomyces lavendulae | L-homoserine | 1.47 | 98 | 0.015 | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase), L-homoserine |
| DcsE (L-serine O-acetyltransferase) | Streptomyces lavendulae | L-serine | 1.58 | 4.9 | 0.32 | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase), L-serine |
| DcsE (L-serine O-acetyltransferase)variant G52A | Streptomyces lavendulae | L-homoserine | 0.22 | 25 | 0.0087 | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase) variant G52A, L-homoserine |
| DcsE (L-serine O-acetyltransferase)variant G52A | Streptomyces lavendulae | L-serine | — | — | 3.7 × 10⁻⁵ | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase) variant G52A, L-serine |
| DcsE (L-serine O-acetyltransferase)variant G52A/P55G | Streptomyces lavendulae | L-homoserine | 0.78 | 2 | 0.4 | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase) variant G52A/P55G, L-homoserine |
| DcsE (L-serine O-acetyltransferase)variant G52A/P55G | Streptomyces lavendulae | L-serine | — | — | 4.8 × 10⁻⁵ | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase) variant G52A/P55G, L-serine |
| DcsE (L-serine O-acetyltransferase)variant P55G | Streptomyces lavendulae | L-homoserine | 0.63 | 1 | 0.63 | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase) variant P55G, L-homoserine |
| DcsE (L-serine O-acetyltransferase)variant P55G | Streptomyces lavendulae | L-serine | 0.62 | 0.5 | 1.23 | pH 8, 30 °C | PMID 23396912 | Open record: DcsE (L-serine O-acetyltransferase) variant P55G, L-serine |
| homoserine transacetylase (HTA) | Haemophilus influenzae | 3-amino-1-propanol | 5 | 71 | 0.046 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), 3-amino-1-propanol |
| homoserine transacetylase (HTA) | Haemophilus influenzae | 4-nitrophenyl acetate | 7.8 | 1.4 | 5.6 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), 4-nitrophenyl acetate |
| homoserine transacetylase (HTA) | Haemophilus influenzae | acetyl-CoAforward reaction (homoserine acetylation) | 92 | 0.14 | 650 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), acetyl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | acetyl-CoAacetyl-CoA hydrolysis in the absence of homoserine | 4.5 | — | — | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), acetyl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | butyryl-CoA | 27 | 0.21 | 130 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), butyryl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | coenzyme A | 30 | 0.62 | 50 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), coenzyme A |
| homoserine transacetylase (HTA) | Haemophilus influenzae | crotonyl-CoA | 15 | 0.13 | 110 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), crotonyl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | D-homoserine | 78 | 4.7 | 17 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), D-homoserine |
| homoserine transacetylase (HTA) | Haemophilus influenzae | glutaryl-CoA | 0.033 | 0.28 | 0.12 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), glutaryl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | L-homoserine | 92 | 0.13 | 710 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), L-homoserine |
| homoserine transacetylase (HTA) | Haemophilus influenzae | O-acetylhomoserine | 30 | 0.85 | 36 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), O-acetylhomoserine |
| homoserine transacetylase (HTA) | Haemophilus influenzae | propionyl-CoA | 30 | 0.09 | 330 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), propionyl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | succinyl-CoA | 0.21 | 0.36 | 0.57 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), succinyl-CoA |
| homoserine transacetylase (HTA) | Haemophilus influenzae | γ-hydroxybutyric acid | 50 | 19 | 1.8 | pH 7.5, 25 °C | PMID 10913262 | Open record: homoserine transacetylase (HTA), γ-hydroxybutyric acid |
| homoserine transacetylase (metA protein) | Bacillus cereus | acetyl coenzyme A | 0.977 | 0.185 | 5.28 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein), acetyl coenzyme A |
| homoserine transacetylase (metA protein) | Bacillus cereus | L-homoserine | — | 0.214 | 4.56 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein), L-homoserine |
| homoserine transacetylase (metA protein)variant E111G | Bacillus cereus | L-homoserine | — | 0.2 | 4.02 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E111G, L-homoserine |
| homoserine transacetylase (metA protein)variant E111G | Bacillus cereus | succinyl coenzyme A | 0.803 | 0.273 | 2.94 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E111G, succinyl coenzyme A |
| homoserine transacetylase (metA protein)variant E237A | Bacillus cereus | acetyl coenzyme A | 0.015 | 0.108 | 0.139 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E237A, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant E237A | Bacillus cereus | L-homoserine | — | 0.85 | 0.0176 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E237A, L-homoserine |
| homoserine transacetylase (metA protein)variant E237D | Bacillus cereus | acetyl coenzyme A | 0.158 | 0.174 | 0.91 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E237D, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant E237D | Bacillus cereus | L-homoserine | — | 0.405 | 0.391 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E237D, L-homoserine |
| homoserine transacetylase (metA protein)variant E237Q | Bacillus cereus | acetyl coenzyme A | 0.052 | 0.143 | 0.361 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E237Q, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant E237Q | Bacillus cereus | L-homoserine | — | 0.287 | 0.18 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E237Q, L-homoserine |
| homoserine transacetylase (metA protein)variant E250A | Bacillus cereus | acetyl coenzyme A | 0.435 | 0.165 | 2.64 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E250A, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant E250A | Bacillus cereus | L-homoserine | — | 2.95 | 0.147 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant E250A, L-homoserine |
| homoserine transacetylase (metA protein)variant K163M | Bacillus cereus | acetyl coenzyme A | 0.328 | 0.266 | 1.23 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant K163M, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant K163M | Bacillus cereus | L-homoserine | — | 2.78 | 0.118 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant K163M, L-homoserine |
| homoserine transacetylase (metA protein)variant K47M | Bacillus cereus | acetyl coenzyme A | 0.07 | 3.07 | 0.0228 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant K47M, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant K47M | Bacillus cereus | L-homoserine | — | 1.38 | 0.0507 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant K47M, L-homoserine |
| homoserine transacetylase (metA protein)variant K47R | Bacillus cereus | acetyl coenzyme A | 0.655 | 1.35 | 0.485 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant K47R, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant K47R | Bacillus cereus | L-homoserine | — | 0.946 | 0.692 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant K47R, L-homoserine |
| homoserine transacetylase (metA protein)variant R249M | Bacillus cereus | acetyl coenzyme A | 0.102 | 0.199 | 0.511 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant R249M, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant R249M | Bacillus cereus | L-homoserine | — | 13.8 | 0.0074 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant R249M, L-homoserine |
| homoserine transacetylase (metA protein)variant S192A | Bacillus cereus | acetyl coenzyme A | 0.543 | 0.249 | 2.18 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant S192A, acetyl coenzyme A |
| homoserine transacetylase (metA protein)variant S192A | Bacillus cereus | L-homoserine | — | 1.02 | 0.533 | pH 7.5, 25 °C | PMID 18216013 | Open record: homoserine transacetylase (metA protein) variant S192A, L-homoserine |